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1/4🧵 New paper out! We built T-ChroNet, a method to track how enhancers and regulatory elements change over time — and figure out who's driving them.
Read more → academic.oup.com/nargab/article…
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Stefano Di Giovenale
266 posts
Stefano Di Giovenale
@StefanoDiggio
Junior Researcher @IREISGufficiale PhD in Data Science
Katılım Kasım 2011
206 Takip Edilen73 Takipçiler
4/4 Available as Python + R packages, scales to 100k+ regions.
Code → github.com/DGStefano/T-Ch…
#Bioinformatics #Epigenomics #Genomics
Français
3/4 We tested it on macrophage activation, mouse liver development, and pediatric leukemia progression. Recovered known regulators, found new ones too, from just ATAC-seq or ChIP-seq.
English
1/4🧵 New paper out! We built T-ChroNet, a method to track how enhancers and regulatory elements change over time — and figure out who's driving them.
Read more → academic.oup.com/nargab/article…
English
Stefano Di Giovenale retweetledi
🔔 Excited for the #FrancescaMartiniPrize for Experimental Thesis in #Oncohaematology 2023! Follow the inspiring journey of last year's winner
@StefanoDiggio.
📷 See you on Dec 1st for the awards!
More info: nanaonlus.org/premio-frances…
#CancerResearch #AML @Biostellasrl
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I want to express my gratitude to the entire team for their support during this time!
I am looking forward to new challenges!
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I sincerely appreciate the enriching six months I've had conducting research at the @meduni in the Barozzi's lab.
Working on exciting projects has been an incredible experience that helped me develop new proficiencies I can bring back to Rome.
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Stefano Di Giovenale retweetledi
🇮🇹Lavorare con colleghi che si mettono in gioco sempre è una fortuna da non sottovalutare!
Congratulazioni @StefanoDiggio 🥳
🇬🇧Working with colleagues who always challange themselves is a fortune not to be underestimated!
Stefano Di Giovenale@StefanoDiggio
Grazie alla commissione per aver riconosciuto positivamente il mio lavoro. Questo premio è una grande motivazione per continuare su questa strada! @Nana_ETS
Italiano
Stefano Di Giovenale retweetledi
Here we demonstrate how epistatic interaction between KEAP1 mutations and associated copy number alterations reduce immunotherapy efficacy sustaining a COLD immune microenvironment. Thanks to all the contributors, incredible scientific journey, and interdisciplinary effort!
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Stefano Di Giovenale retweetledi
Il vincitore del #PremioFrancescaMartini è Stefano Di Giovenale, con Tesi su "La caratterizzazione del reguloma della Leucemia Linfoblastica Acuta pediatrica rivela meccanismi di evoluzione tumorale"
👉🏻nanaonlus.org/premio-frances…
#CancerResearch #leucemie #biostella #SciComm
Italiano
Grazie alla commissione per aver riconosciuto positivamente il mio lavoro. Questo premio è una grande motivazione per continuare su questa strada! @Nana_ETS
Nana ETS@Nana_ETS
🏆 Proclamazione del vincitore Dott.Stefano di Giovenale , Università di Roma Tor Vergata, Iscritto al Dottorato di ricerca in Data Science, con una Tesi su "La caratterizzazione del reguloma della Leucemia Linfoblastica Acuta pediatrica rivela meccanismi di evoluzione tumorale".
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Stefano Di Giovenale retweetledi
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Stefano Di Giovenale retweetledi
Super excited to see my first graphical #abstract on the #cover of @JTOonline!
The latest review by @stescalera & @MaugeriSacca about the molecular functions of the KEAP1-NRF2 pathway, its role in #lungcancer and how KEAP1/NFE2L2 mutations reduce the efficacy of treatments💊
Rome, Lazio 🇮🇹 English
Thanks to @PaoloDiTommaso , @EvanFloden and @SeqeraLabs for the fantastic merch pack. It's a real pleasure to be part of the @nextflowio community.
@nf_core
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Stefano Di Giovenale retweetledi
Review of multifaceted biological functions of the KEAP1/NRF2 pathway in #lungcancer, expected consequences of these alterations, & key clinical studies. Genomic predictors should be conceived relying on the concept of epistatic interactions. bit.ly/3zofJkC #LCSM
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Our new study is now reachable on Biorxiv. We evaluated the enhancers’ involvement in the Pediatric Acute Lymphoblastic Leukaemia progression! Follow the link for the complete paper. biorxiv.org/content/10.110…
#Genomics #Biology #Epigenomics
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Stefano Di Giovenale retweetledi
Excited to share the new preprint from Fanciulli lab @IREISGufficiale on biorxiv.org/cgi/content/sh… . We wanted to know how Multiple Myeloma cells cope with transcriptional stress, and we found that: Stress UP -> Che-1 / NEAT1 UP -> DNA: RNA hybrids UP -> IFN UP -> Poor prognosis.
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Stefano Di Giovenale retweetledi
"Laureata in biologia molecolare" che stamattina sei entrata nel negozio dei miei genitori a spiegare che gli verrà il Parkinson a causa dei metalli pesanti contenuti nel vaccino anticovid, consigliando anche degli integratori per prevenire questi effetti
1/3
Italiano
Thank you to #EMBLIIT2021 that gave me the opportunity to show my first poster. This is certainly the first step in my research career.
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Stefano Di Giovenale retweetledi
#propagandalive "Basterebbe una volta": il cartoon del genio @Makkox a @welikeduel la7.it/propagandalive…
Italiano