Sumner L Norman

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Sumner L Norman

Sumner L Norman

@SumnerLN

co-founder @merge

California, USA Katılım Mayıs 2016
926 Takip Edilen3.9K Takipçiler
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Sumner L Norman
Sumner L Norman@SumnerLN·
Ecstatic to announce Merge Labs! 🧠🚀 I’m honored to work alongside my co-founders—Tyson Aflalo, @mikhailshapiro, @sandroherbig, @alexblania, and @sama on bridging biological and artificial intelligence. They’re *the* team to take on a mission this ambitious. We’re grateful to have partners like @OpenAI who share a long-term view on what it takes to build foundational technology. If you want to work on hard, foundational neurotech problems, come build with us.
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U.S. National Science Foundation
NSF announces $1.5B NSF X-Labs initiative to pursue generational breakthrough science efforts. NSF X-Labs will scale a new generation of transformative independent research organizations to advance breakthrough science outside of traditional institutions. nsf.gov/news/nsf-annou…
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Tyler Maran
Tyler Maran@TylerMaran·
venice was built on a sandbar in 421 ad what's stopping us?
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VicVRad
VicVRad@VicVRad·
@SumnerLN I’d convince my salience network to stop giving the DMN admin privileges
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Sumner L Norman
Sumner L Norman@SumnerLN·
If you had 10x the agency you feel you have now, what would you do?
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Tom Kalil
Tom Kalil@tkalil2050·
I am very proud of the progress that @RenPhilanthropy and its partners have made in our first two years – $533 million in funding for science and technology, launching more than 20 programs, training 45 scientists and innovators to design transformative, ARPA-style programs, partnering with the UK, German and Japanese governments, and publishing our first 10 playbooks on the “how” of innovation. Our field strategists are accelerating progress in areas such as AI for fundamental math, AI for early literacy, geologic hydrogen, stabilizing the Arctic climate, low-cost space telescopes, and open-source software for life sciences. Thanks to all the philanthropists, foundations, and governments that have supported our work – and please reach out if you’d like to collaborate. The best is yet to come!
Renaissance Philanthropy@RenPhilanthropy

Our second annual report is live! Two years ago, we launched @RenPhilanthropy to fuel a 21st century renaissance by increasing the ambition of philanthropists, scientists and innovators. Here's what we've achieved: 🧵

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Sumner L Norman
Sumner L Norman@SumnerLN·
Once in a while, science expands human capabilities. This is one such case. Super cool. "Oz enables display of colors that lie beyond the well- known, bounded color gamut of natural human vision" "Subjects report that olo in our proto- type system appears blue-green of unprecedented saturation" science.org/doi/10.1126/sc…
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Dwarkesh Patel
Dwarkesh Patel@dwarkesh_sp·
.@AdamMarblestone thinks it might cost ~low billions to map the human brain connectome. The benefit is getting answers about the brain’s secret sauce: esp. why are humans so much more sample- and energy-efficient. If labs are going to be spending trillions of dollars on compute by the end of the decade, Adam's pitch is: give him 1/100th of that to actually figure out these big questions about intelligence.
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Ilan Gur
Ilan Gur@ilangur·
We're on the precipice of massive sociotechnical transformation. In thinking about what root-level technologies will matter most, I keep coming back to two themes. The first is Coordination. Non-linear and asymmetric technology acceleration is going to push things way out of equilibrium over the next couple of decades. We'll need counterforces that hold and pull society together. New technologies, institutions, and movements that can: - amplify trust, connection and collaboration. - drive collective flourishing while preserving individuality. - get us closer to the pareto frontier of shareholder and social value creation. The second is Neurotechnology. Neurological disorders are humanity's biggest barrier to productivity, agency, happiness, and peace. Meanwhile, powerful AI is about to challenge the very foundations of human identity and experience. Applying frontier engineering and invention to frontier neuroscience, I think we can massively shift the trajectory of human flourishing: - understand what makes us “us.” - gain control over psychiatric disorders, learning, cognition, and bias. - solve alignment and symbiosis with hyperintelligent machines. - protect, enhance & preserve the human experience. Thrilled to explore these topics as part of @RenPhilanthropy's growing community of scientists, funders, and entrepreneurs working to slingshot humanity into a better future!
Renaissance Philanthropy@RenPhilanthropy

We are beyond excited to announce @ilangur as a Senior Fellow at @RenPhilanthropy. Ilan was the founding CEO of @ARIA_research, is the founder of Activate, supporting scientists and researchers to turn breakthrough research into world-changing products and businesses, a founding Program Director at @ARPAE, and the founder of two startups. At Renaissance Philanthropy, Ilan will scope new opportunities across neurotechnology and frontier science, driven by a deep belief in our collective potential to drive a step change in human flourishing. Ilan has been a long-standing collaborator and friend of our community and we couldn't be more thrilled to make it official. To explore this work, get in touch: info@renphil.org

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Georgia Channing
Georgia Channing@cgeorgiaw·
Every drug × every target 📊 228 targets 💊 1,397 FDA-approved compounds 🔬 558K interactions @EvEBiotech's largest data release ever adds 29 new GPCRs in the Gs pathway + 1 kinase (PDGFRa-D842V) All on @huggingface 🤗
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Sumner L Norman
Sumner L Norman@SumnerLN·
Sure, there's a lot of slop. But my backlog of quality content from brilliant people that I've gotten to know and trust (either in their artifacts or IRL) has never been larger. So much incredible progress being made right now.
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Ashlee Vance
Ashlee Vance@ashleevance·
Tomorrow, @sama and @gdb will be on a podcast together for the first time ever. And they will give an exact date for the arrival of AGI. New models, the trial with @elonmusk, @AnthropicAI beef, Sam personal drama, the future of compute buys, @kyliebytes and I do it all. @corememory episode 67 hits on the Substack only. If you want the goods, it's time to sub up corememory.com The Core Memory pod is on all major platforms and brought to you by @brexHQ and @e1ventures because they have great taste.
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Sumner L Norman
Sumner L Norman@SumnerLN·
🥹
Reid Wiseman@astro_reid

Only one chance in this lifetime… Like watching sunset at the beach from the most foreign seat in the cosmos, I couldn’t resist a cell phone video of Earthset. You can hear the shutter on the Nikon as @Astro_Christina is hammering away on 3-shot brackets and capturing those exceptional Earthset photos through the 400mm lens. @AstroVicGlover was in window 3 watching with @Astro_Jeremy next to him. I could barely see the Moon through the docking hatch window but the iPhone was the perfect size to catch the view…this is uncropped, uncut with 8x zoom which is quite comparable to the view of the human eye. Enjoy.

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Sumner L Norman
Sumner L Norman@SumnerLN·
The 2026 One Mind cohort includes some seriously sharp minds and ambitious companies. Go check them out!
One Mind Accelerator@OMAccelerator

The final day of the 2026 One Mind Accelerator closing week marked the culmination of an incredible journey, bringing the cohort together for Demo Day! The day began with breakfast at Baylands Café in Palo Alto, followed by a group walk along the Baylands, offering a moment to connect, recharge, and reflect ahead of the day’s events. The afternoon opened with the Frontiers in Mental Health Summit, featuring remarks from CEO of @OneMindOrg, Kathleen M. Pike, PhD, and a series of forward-looking discussions on the future of the field. From market trends and opportunities with Hemingway Founder @thesteveduke, to emerging insights on metabolic psychiatry, brain-computer interfaces, and neuroadaptive intelligence from Drs. Scott C. Fears (@Amae_Health & @UCLA), @SumnerLN (@merge), @MaryamShanechi (@USC), and @NinaVasan, MD, MBA (@Stanford), the session highlighted the innovation shaping what’s next in mental health.

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Seth Bannon
Seth Bannon@sethbannon·
NASA just quietly published something incredible. A map of how we build a permanent human presence off Earth. It’s called the Moon Base User’s Guide. Here's what's in it! 🧵
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Sumner L Norman
Sumner L Norman@SumnerLN·
How do neurons create visual imagery? Phenomenal work from @WadiaVarun @doristsao @UeliRutishauser and colleagues at Caltech and Cedars-Sinai. I’m looking forward to imagining entire scenes into existence for others to see/perceive. 🍎
VarunWadia@WadiaVarun

1/8 Our preprint is now a peer-reviewed paper :) Big thanks to our reviewers who pushed us to examine our results more carefully and Olivier Wyart (headquarter.paris) for the exquisite visual. science.org/doi/10.1126/sc…

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Patrick Mineault
Patrick Mineault@patrickmineault·
Stoked this is finally out! We ask: how can we simulate the brain from the bottom up? It's not sufficient to grab the connectome and wire it up in silico! We need 1) ultrastructure 2) (causal) calibration data 3) functional data. Then we can build a simulation compiler. 1/
Kording Lab 🦖@KordingLab

Preprint out arguing that we should build the techology to translate (compile) molecularly annotated connectomes into dynamics. I think this is incredibly important. arxiv.org/abs/2603.25713

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Wojciech Zaremba
Wojciech Zaremba@woj_zaremba·
Life update — I’m moving to the OpenAI Foundation to lead AI resilience. AGI will bring tremendous benefits and potential disruptions, such as impacts on children and youth, model malfunctions, emergent bio-risks, and more. AI resilience is about minimizing these disruptions so society can fully realize the benefits. openaifoundation.org/news/update-on…
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