Moved to @sunitjain.bsky.social

Two updates I've been sitting on: 1. I'm an Anthropic Claude Community Ambassador for the SF Bay Area 🌊 2. Speaking at Code with Claude next week on why domain experts still matter in the age of AI — drawn from what we're building at @BioKEAAI claude.com/code-with-clau…

Read the full blog on our Substack: substack.com/home/post/p-19…

In our new blog post, we team up with @NVIDIAHealth to make it possible to map how drug effects cascades through gene regulatory networks.

It was a pleasure meeting members of the @BerkeleyML community last week! Our team always enjoys connecting with talented students who are passionate about ML x Bio 💙 We’re excited to continue these conversations and are open to speaking with prospective internship and full-time candidates. Check out our careers page (link in comments)

We build datasets, train AI models, and use them for the ultimate goal of discovering and developing new medicines, starting from oncology. This joint venture represents another major step towards that and a preview of the business models enabled by our platform.

Alloy and Tahoe are seeding the new company and will co-develop the assets leveraging the biologics capabilities of Alloy coupled with Tahoe's datasets and AI models.

We have talked a lot about the datasets & virtual cell models that we are building @tahoe_ai. Today, we are announcing a joint venture with 82VS, the Venture Studio of Alloy Therapeutics to develop antibody drug conjugates for two novel targets, discovered using our technology.

Over the last year, few institutions have done more for the quest towards virtual cell models than @tahoe_ai, @arcinstitute, and @officialbiohub. Today, in a landmark partnership, we are teaming up to generate the next definitive dataset for virtual cell models, using Tahoe’s Mosaic Technology. This is first of its kind: multi-million dollar investment from each of these orgs coupled with the massive scale Tahoe’s technology enables. 120M+ cells, 225K unique interactions. We will build on the gigantic success of Tahoe-100M (downloaded 250K+ times in less than a year), and the lasting impact of Arc’s scBaseCamp, and Biohub’s CELL x GENE, to fuel the next generation of virtual cell models, whether developed by us or others. It’s morning in biology! Let’s build.

@nalidoust @arcinstitute @officialbiohub Read more about the partnership: Official Press Release: tahoebio.ai/news/tahoe-arc… Story by GEN News: genengnews.com/topics/artific…

Phylogenetically and metabolically diverse active carbon-fixing microbes reside in mangrove sediments microbiomejournal.biomedcentral.com/articles/10.11…

new work from @CIGLR_UM finds that "the Great Lakes have entered a new era of temperature extremes". nature.com/articles/s4324…

This is not true! Any phage scientist could tell you that phage are everywhere from sewage, to rivers, to human skin and human gut. Literally everywhere. They are not a barometer of river purity or anything else.

If you're a scientist that serves on an NSF panel that got cancelled today, I'd love to talk to you about it for an NPR story. DM, email or reach out on signal.

PLEASE SHARE! 📢 #CIGLR is excited to announce the opening of our 2025 #GreatLakes Summer Fellow applications! There are 7 full-time, 12-week positions paying $10,000 each. Applications are due 09 Feb 2025 at 11:59 pm EST! Eligibility & how to apply: ciglr.seas.umich.edu/2025-great-lak…

OUT NOW Unraveling viral ecology and evolution over twenty years in a freshwater lake @KarthikGeomicro & co nature.com/articles/s4156…

Check out our last pub. from @mfgrp lab! We discovered that skin commensal microbes induce systemic and local B cell responses upon colonization and took advantage of this knowledge to create topical vaccines using engineered skin microbes. Please read the thread for details.

Come join us! If you use AI (loosely defined) for any microbiology applications, consider applying for these faculty positions. Great dept with amazing colleagues and a supportive environment.

If you are interested in prophages, we have a new database: Prophage-DB. Check it out and all feedback is welcome biorxiv.org/cgi/content/sh…

In the past few weeks, there's been an explosion of new tools for programming DNA and RNA 🧬 A thread with everything you need to know about these new results:

Metagenome taxonomy profilers usually ignore unknown species. SingleM is an accurate profiler which doesn't, even detecting phyla with no MAGs. We applied it to 250,000 metagenomes- in environmental samples 75% lack a genome/MAG (abundance-weighted). A 🧵biorxiv.org/content/10.110…