
Tanja Spanic
1.3K posts



Sooooo ready for ESMO BREAST 2027 MILAN! 🇮🇹

Novel treatment strategies and key research priorities for patients with breast cancer and central nervous system (CNS) metastases nature.com/articles/s4152… Despite advances in surgery, radiation, and CNS-active therapies, #BreastCancer –related CNS 🧠metastases remain associated with poor outcomes. In 2023, the Breast International Group and the NCI’s National Clinical Trials Network convened a CNS working group to identify key challenges and collaborative solutions. This review summarizes discussions on CNS screening, treatment sequencing in HER2🧬positive disease, leptomeningeal disease management, and the need for innovative, biology-driven clinical trials to improve treatment and prevention. @JerzakKasia @ElisaAgostinett @BrainTumorDoc @CareyAnders1 @VriesElisabeth @SahgalArjun @drsarahsam @paspears88 @MammaMiaMagazin @cancermedic @nlinmd @BIGxResearch



This week is Adolescent & Young Adult Cancer Awareness Week. This week focuses on ~89,000 people 15–39 diagnosed w/ cancer annually. This week highlights the unique challenges faced: lower survival improvements, fertility, financial stress, & disruption to education & careers!




What happened this week in #BreastCancer: 1️⃣ CDK4/6 inhibitor timing in advanced HR+/HER2- disease Phase III SONIA data showed no OS difference between first-line vs second-line CDK4/6 inhibition with higher toxicity when used first-line, supporting more individualized sequencing decisions and potential de-escalation for selected patients as summarized in SONIA trial (phase III) results. jamanetwork.com/journals/jamao…














































