Randy Bruno
2.7K posts
@TheBrunoCortex
Neuroscientist investigating the role of cerebral cortex and thalamus in our behavior
Today in @Nature, we report MouseMapper: foundation-model AI to map disease perturbations across the entire mouse body cell-by-cell. In obesity, it revealed body-wide inflammation & unexpected facial nerve damage. 🧵👇🔉 nature.com/articles/s4158… led by @Dorie00 & @yingchen733
I don't think enough people realize we're about five years out from people going to rehab for phones
Researchers at EPFL proved your AI is lying to you. Not sometimes. Most of the time. They built one of the hardest hallucination tests ever made with Max Planck Institute. 950 questions. Four domains where being wrong actually hurts. Legal. Medical. Research. Coding. Then they ran every top model on it. The results. GPT-5. Wrong 71.8% of the time. Claude Opus 4.5. Wrong 60% of the time. Gemini 3 Pro. Wrong 61.9% of the time. DeepSeek Reasoner. Wrong 76.8% of the time. These are the smartest AI models on Earth. The ones you trust with your career. Your health. Your money. You think turning on web search fixes it. It doesn't. Claude Opus 4.5 with web search. Still wrong 30.2% of the time. GPT-5.2 thinking with web search. Still wrong 38.2% of the time. The internet attached. Still lying to you in 1 out of every 3 answers. Now the part that should scare you. Medical questions. The one place being wrong can kill you. GPT-5 hallucinated 92.8% of the time on medical guidelines. Claude Haiku 4.5 hallucinated 95.7% of the time. Gemini 3 Flash hallucinated 89% of the time. Nine out of ten medical answers from popular AI models. Wrong. It gets worse. The longer you talk to it, the more it lies. Early mistakes cascade. The model starts citing its own earlier hallucinations as facts. Your third message is more wrong than your first. The paper, in its own words: "hallucinations remain substantial even with web search." This is what hundreds of millions of people are doing right now. Asking software that lies in the majority of its answers. About their health. About their job. About their legal case. About their code. Most are not checking. Most never will. But please. Keep using ChatGPT for medical advice. The doctors need a break. arxiv.org/abs/2602.01031
Students who used AI to study remembered less than those who did not.
A tenured neuroscientist died by suicide after false accusations against her led to discrimination against her incl breaking up her research team, reassigning her grants to other faculty & ultimately closing her lab after she was exonerated making it impossible for her to apply for future funding according to the complaint. After the investigation was closed & she was exonerated the university allegedly continued discriminating against her. “cut her salary for lack of funding of her research during the NIH investigation, raised new requirements she had to meet to restore her funded status, gave her only a limited chance to meet them, and refused to assign back to her a prior grant that had been taken away from her but was still active."
Interhemispheric transfer of sensory and working memory information is not a passive process but an active one governed by top-down influence. The direction of this data flow between brain hemispheres depends entirely on the behavioral strategy currently in use. doi.org/10.64898/2026.…
