
Holley Lab
141 posts

Holley Lab
@TheHolleyLab
The Holley Lab at Duke University works to discover how non-coding RNAs and epitranscriptomic RNA modifications contribute to heart disease.




Last year, $9B of the $35B that the National Institutes of Health (NIH) granted for research was used for administrative overhead, what is known as “indirect costs.” Today, NIH lowered the maximum indirect cost rate research institutions can charge the government to 15%, above what many major foundations allow and much lower than the 60%+ that some institutions charge the government today. This change will save more than $4B a year effective immediately.




Here’s a timeline of my career Orange=grants submitted Green=grants funded Lessons learned? -persistence pays -scientist=professional writer -grant writing makes the science better -scientist=entrepreneur. Not every “invention” is a hit (learned this from @ABCSharkTank)













New methods for high-throughput Nm mapping have been developed in recent years, but challenges remain in accurate mapping and manipulation of Nm to understand its function and disease relevance #RNA #RNAmods bit.ly/4aUERje













