Translational Cancer Epigenomics

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Translational Cancer Epigenomics

Translational Cancer Epigenomics

@TransCanEpi

Official account Section Translational Cancer Epigenomics @TMO_Heidelberg @NCT_HD @DKFZ, #epigenomics, #hematopoiesis, #JMML, #singleCell, #precisiononcology

Heidelberg, Deutschland Katılım Haziran 2022
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Blood Cancer Discovery
Blood Cancer Discovery@BCD_AACR·
Now online: Molecular Plasticity Results in Oncofetal Reprogramming and Therapeutic Vulnerabilities in Juvenile Myelomonocytic Leukemia doi.org/10.1158/2643-3…
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Ankur Sharma
Ankur Sharma@asharmaiisc·
Here, in this @Cancer_Cell mini-review, we highlight recent advances in understanding oncofetal reprogramming and explore its emerging potential as a biomarker and therapeutic target in cancer research. @FGinhoux sciencedirect.com/science/articl…
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Daniel Lipka
Daniel Lipka@dblipka1·
Yet another work that investigates the molecular underpinnings of #childhood #leukemia and tries to understand what drives disease #heterogeneity across patients. Congratulations to this amazing work @Elvin_Wag and colleagues!
Elvin Wagenblast@Elvin_Wag

Thrilled to share at #ASH25 that our lab’s first paper is now published in @CD_AACR! 🎉 We reveal how developmental context shapes oncofusion-driven high-risk pediatric acute myeloid leukemia. aacrjournals.org/cancerdiscover…

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Daniel Lipka
Daniel Lipka@dblipka1·
Interested in DNA methylation and want to hear what we can learn from it regarding lineage commitment decisions in #hematopoiesis? #ASH25 #epigenomics
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Daniel Lipka
Daniel Lipka@dblipka1·
Happy to see our study finally published in @BCD_AACR! 🎉 Thanks again to the lead authors @mp_hartmann, Maximilian Schönung and all collaborators who helped to put together the bits and pieces of this exciting story! 🙏👏
Tanya Bondar@_TanyaBondar_

Just published in @BCD_AACR: Molecular Plasticity Results in #Oncofetal #Reprogramming and Therapeutic Vulnerabilities in JMML, by @mp_hartmann @dlipka1 Check out new insights into cell-of-origin, and repurposing anti-CD52. doi.org/10.1158/2643-3…

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Ruud Delwel
Ruud Delwel@DelwelRuud·
Breaking news! The Erasmus Hematology Lectures start again on September 1 with Marc Dawson. As Marc presents from Australia this lecture will be at 1pm CEST! All other lecture will be at 4PM CEST! Check out the complete list of speakers for 2025! Enjoy and share the news!
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Daniel Lipka
Daniel Lipka@dblipka1·
We are hiring! For our Translational Cancer Epigenomics team @DKFZ and @NCT_HD we are looking for a talented postdoc interested in research on heme malignancies and #epigenetics. 🧬🧪🩸 Interested? 👉See jobs.dkfz.de/en/jobs/167620… or DM me!
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Mark Hartmann
Mark Hartmann@mp_hartmann·
Excited to announce the upcoming 80th Heidelberg Grand Round on "Developmental Signatures and Molecular Plasticity in Cancer"! Join us in Heidelberg, on Nov 14, 2024, from 4:00-6:00 PM–free of charge! Explore #Cancer as a developmental disease! @DKFZ @NCT_HD @uniklinik_hd
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Daniel Lipka
Daniel Lipka@dblipka1·
This collaborative effort demonstrates that ectopic expression of MNX1 is a driver event in a subset of adult del(7q) AML. #AML #leukemia #epigenomics
Etienne Sollier@EtienneSollier

I'm excited to share our preprint "Pyjacker identifies enhancer hijacking events in acute myeloid leukemia including MNX1 activation via deletion 7q": doi.org/10.1101/2024.0…. This is my main PhD work and a massive collaborative effort. 🧵👇

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Etienne Sollier
Etienne Sollier@EtienneSollier·
I'm excited to share our preprint "Pyjacker identifies enhancer hijacking events in acute myeloid leukemia including MNX1 activation via deletion 7q": doi.org/10.1101/2024.0…. This is my main PhD work and a massive collaborative effort. 🧵👇
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Keşfet

@JianXuLab @mp_hartmann @dblipka1 @BCD_AACR @CD_AACR @GauravA_UK @bloodgenes @_ruslansoldatov