Scott E Delacroix Jr M.D.

Radical Cystectomy shouldn't be the only conversation after EV-Pembro.

36 years of loyal service and more cold beers than we could count. RIP to a garage legend 🍻

Today on Clinical Trials Day, we honor patients, researchers & professionals advancing cancer care. Every study brings new hope. Thanks to all for helping to move oncology research forward. #ClinicalTrialsDay #CTD2026 #ResearchRising

N=597

May is #BladderCancerAwarenessMonth. We're highlighting studies in our GU portfolio. NRG-GU015 The ARCHER Study is enrolling patients with cT2-cT3 MIBC that is clinically node negative. Learn more ➡️ ow.ly/RqQm50YZJ59 @UroCancer @HimanshuNagarMD

After 10 years as @UroOnc PD at @UTMDAnderson, Happy to announce @KKBree will assume the role As APD, she has shown an unique ability 2 connect w/fellows while maintaining the rigor needed to train today’s Uro Oncs Proud of her leadership + excited for the future #oncsurgery

@tomboike @DietCoke Cans! Are you kidding me. Does anyone actually drink the last couple sips out of a bottle? Have you tried the 16oz cans….

@UroCancer @DietCoke It worked, we have moved the needle through activism! Now to decide, cans or bottles!

What do we want! Diet Coke for everyone!

@ChapinMD @Marriott @DietCoke Nope something to do with how the chickens are treated before they become and sandwich.

@UroCancer @Marriott @DietCoke Circumcision?

#AUA2026 conference hotel with massive protest. Not just me that is upset about @Marriott still serving Diet Pepsi instead of @DietCoke

@ysaralee @Marriott @DietCoke Chicken sandwich was excellent.

@UroCancer @Marriott @DietCoke I saw this! I was worried they were protesting us for some reason… but it turns out it’s about freeing the chickens?!

@PCaParker @ChapinMD @DrSpratticus @Prof_Nick_James @NCCN @Uroweb @AmarUKishan @TylerSbrt @HimanshuNagarMD @seanmmcbride @ChrisSweens1 @ChadTangMD @piet_ost @_ShankarSiva @DrAndrewLoblaw One reason (not the only) —Progression within the first 6 months of starting SST. Two step enrollment (systemic litmus) with randomization after the 6 months. Correlatives gathered from day 1 though. N=patients randomized (not enrolled).

@ChapinMD @DrSpratticus @Prof_Nick_James @UroCancer @NCCN @Uroweb @AmarUKishan @TylerSbrt @HimanshuNagarMD @seanmmcbride @ChrisSweens1 @ChadTangMD @piet_ost @_ShankarSiva @DrAndrewLoblaw What do you mean by “fallen off”?

For those that couldnt make it to #AUA26, especially those at #ESTRO26, here were some of the slides for the "Pro" RT to primary in M1a disease. @TylerSbrt @UroCancer @CaPsurvivorship @PCaParker @Prof_Nick_James @wandering_gu

That questions assumes patients aren’t on trial. NRG has a trial exactly for this. Patients are searching for multidisciplinary expertise beyond consolidative cystectomy. NRG GU015 (Archer) and SWOG 2427 (Bright) will help bring answer this. The trials are being done. In prostate —the trial is there—SWOG 1802….need enrollment to answer.

@DrSpratticus @TylerSbrt @UroCancer @CaPsurvivorship @PCaParker @Prof_Nick_James @wandering_gu Point well taken Dr Spratt 👍🏻 What would you say to your Rad Onc colleagues who are trying to substitute cystectomy by RT in cCR after neoadjuvant therapy? Why is this substitution fine and not the substitution of RT by RP ?

For #BladderCancerAwarenessMonth, we're highlighting NRG studies in our GU portfolio that are currently enrolling patients - NRG-GU014, The PARRC Trial is enrolling patients with high-grade T1 #bladdercancer. Learn more ➡️ow.ly/fJe950YZI4N @BrianBaumannMD @UroCancer

Debate resulted in consensus: support clinical trials! We don’t know unless we investigate. What an honor to discuss management of PSMA-only M1a #ProstateCancer with Jeff Karnes @CaPsurvivorship @UroCancer @DrSpratticus #AUA26 @urogeek

My favorite slide from exciting #AUA26 crossfire discussion so far by @TylerSbrt on M1a PCA. Beware of indirect evidence. We have been burnt before.

@Marriott what happened to the partnership with Coke? This Diet Pepsi just doesn’t cut it. #aua2026

@tompowles1 @montypal Q: Is there a reason why the chemoRT arm does not allow neoadj EVP? With 302/303 showing clear benefit of addition to local tx, the control arm of chemoRT alone feels handicapped. NRG GU15 and S2427 both allow EVP as SOC leading into CRT/IO-RT as example.

@RayWangonc That’s not true. Most people are reasonable when their concerns are acknowledged in a polite and reasonable manner.

Struggle to see consenting physician not offering EVP. Trial only makes sense in places that don’t have EVP access. “We have a drug combination that is a sea change in bladder cancer but there’s a 50% chance you will not get it if you enroll on this trial.” Just because you decline RC (as this trial allows) shouldn’t deny access to EVP.