Van Wallenstein

@Brandon_Beaber Great! Does the study include data on b cells and clinical or radiological activity in EID vs SID?

meta analysis of 17 studies on b-cell depleters (rituximab, briumvi, ocrevus) standard vs. extended interval dosing (taking it less often) have comparable results in terms of relapse rates and MRI activity, though no major difference in serious infections pubmed.ncbi.nlm.nih.gov/41890616/

@nirmalregency Love your tweetorials! Great as always!

23/ The take-home slide: Luckily TGA is a benign condition. Brain's reboot mechanism, perhaps.

1/ As we advance in life, we collect NEW memories. What if ⓵ fine day that ability gets taken away? A 1st first-hand experience in 30 years of #neurology practice. 🧵 BIT LONG 1|23

🧠Refractory seizures + multifocal cortical–subcortical MRI lesions? Think GABAₐR-antibody encephalitis & live cell-based assays (native antigen conformation) to avoid misdiagnosis with fixed assays. doi.org/10.1136/pn-202… #Neuroimmunology #Encephalitis #GABAAR

DANCE Syndrome A rare, severe neurotoxic condition in young children (usually <5 years) caused by acute dextromethorphan ingestion, characterized by sudden, profound neurological dysfunction and specific MR imaging findings of cytotoxic edema in the cerebellum. It presents with rapid onset unresponsiveness, resembling a com. Mimics the opioid-related POUNCE syndrome but is specifically associated with cough syrup misuse or accidental overdose. Prompt recognition and treatment—potentially involving ICU support, and in some cases, naloxone or steroids—are crucial for a good prognosis. ajnr.org/content/46/2/3…

Alaaf & Helau! Der #Karneval ist da! Nazis verarschen ist wunderbar! 🥳🥳🥳 #Rosenmontagszug #Wochenstart #Vetternwirtschaft #Rosenmontag #Start_in_die_Woche

Algorithm for management of acute ischemic stroke eligible for EVT DVO: distal vessel occlusion EVT: endovascular thrombectomy IDD: insufficient data to determine LVO: large vessel occlusion mRS: modified Rankin scale MVO: medium vessel occlusion

What is the current evidence for the use of hematopoietic stem cell transplantation in multiple sclerosis? @JeffCohenMD (@ClevelandClinic) shares insights in this interview: 👉ow.ly/pbHQ50Yekvl👈 #ACTRIMS #MSResearch #ACTRIMSForum

This is amazing: this lady created a device that can control her balance, from a video game controller!!! What a time to he alive

The February #Neurology of Systemic Disease issue, guest edited by @AaronLBerkowitz, is now available at hubs.la/Q041NYWB0! @AANmember @LyellJ #NeuroX #MedEd

Syncope vs Seizure Fainting by love in Philadelphia Museum of Art The Doctor's Visit by Jan Steen #Neurology #Seizure #Syncope #Neuroscience 1/

🧵👇Cerebral Amyloid Angiopathy🩸🧠 Illustrations and tweetorials on CAA, SVD and related disorders by @a_charidimou #NeuroTwitter #stroke #Neurology #neuropath #stroke #dementia #Alzheimers #biomarker #brain #MedStudentTwitter #AmyloidAngiopathy #CAA #cSVD

@bobvarkey Could you DM or post the reference?

Do you know the difference between Optic perineuritis (OPN) and Optic neuritis (ON)? OPN is a orbital inflammatory disease characterized by inflammation of the optic nerve sheath. It is associated with infections or inflammatory diseases like Temporal arteritis, Sarcoidosis or vasculitis. OPN shows a 'tram-track' sign on Contrast axial images and a 'Donut' sign on coronal imaging. Optic neuritis, which is more common, involves only the myelin sheath of the optic nerve in classic CNS demyelinating diseases like. MS, NMO or MOG. ON shows a more uniform enhancement of the optic nerve

youtu.be/EpDQap8piZ8?si… "Guck ned so, Halts Maul, geh weider." #badesalz #gert #knebel #hesse

@teachplaygrub @caseyalbin @neurogenicpoet @Divyani_Garg @rohitmarawar @MedinaRiojaMD @Tracey1milligan @a_charidimou @rkchoi @zach_london @DrKentris @AaronLBerkowitz @CAlejandroneuro @LyellJ @OligoclonalBand @drpradeepck Take home points from recent case report. ahajournals.org/doi/10.1161/ST… @drsthanus

@teachplaygrub Keep it up, I almost daily recommend your posts to my juniors!

INCREDIBLE! 😱 A few years ago, I decided to post my teaching on social media, and now just 3 years later, I’ve been selected as Most effective radiology educator by Aunt Minnie!! Thank you to Aunt Minnie and to all of you! I taught like this for years but it was only when all of YOU started sharing my content that I was able to really reach people and make a difference! Each one of you made this possible and I’m so grateful!!! @AuntMinnie

How to remember the revised McDonalds criteria for MS in 2025!

Thrilled to share the 2024 revisions of the diagnostic Mc Donald criteria and companion papers @ECTRIMS @mssociety @MSIntFederation @vallhebron @FundacioEM @esclerosiseme @cemcat_em @ACTRIMS @EuropeanCharcot @TheLancetNeuro @UABBarcelona @u_medicina linkedin.com/posts/xaviermo…

AI-driven reclassification of multiple sclerosis progression nature.com/articles/s4159…

@Brandon_Beaber @drbarrysinger Here is another example on accidental exposure throughout pregnancy pubmed.ncbi.nlm.nih.gov/39524100/

@drbarrysinger Very unusual indeed. This is very different from accidental exposure early in pregnancy.

How dangerous is in utero exposure of ocrevus to the fetus? This case report found absent b-cells at birth "B-cell reconstitution occurred at age 4 months" and "normal production of immunoglobulins and responses to vaccines noted at age 1 year." publications.aap.org/pediatrics/art…