Vanguard Laboratory

@SolutreanDACA @tread_on_them @Krysia830073 Bottom of the page, Working on updating the website to make more clear. vanguardlaboratory.com/peptide-testin… all peptides/small molecules $250 purity/ID, $550 purity/quant/endotoxins/sterility, & 700 for everything plus metals. no charge for additional sterility vials. Amino Acid analysis

@tread_on_them @Krysia830073 @Vanguard_Lab what prices? none of that is disclosed.

@BrianSuttererMD @oasishealthapp LMNT is not a client but we have tested the product after seeing these reports and it has always been well under Prop 65 limits. We actually keep it stocked in our break room for employees.

Maybe just sit the next few out until you can learn how to interpret and report tests @oasishealthapp

Another strong round of external proficiency testing for Vanguard Laboratory. In LGC PHARMASSURE Round 96, Vanguard achieved: • 6 out of 6 assessments satisfactory • 0 questionable results • 0 unsatisfactory results This round included pharmaceutical and dietary supplement matrices, with successful performance in: • HPLC active ingredient quantification in throat lozenges • Microbiological sterility testing, including correct identification of contaminated and sterile samples under USP <71> External proficiency testing is one of the ways we verify that our methods, instruments, and analysts are performing consistently against independent benchmarks. Vanguard participates in proficiency testing quarterly across a broad range of analytes and technologies, including endotoxins, API quantification, sterility, aerobic plate count, E. coli, Salmonella, nitrates, water activity, pesticides, residual solvents, and more. Our PT program supports work across LC-MS/MS, GC-FID, GC-MS, HPLC, UV-Vis, PCR, wet bench chemistry, ICP-MS, ELISA, and related instrumentation. Consistent, accredited performance matters , especially when results are used to make real quality decisions.

@Krysia830073 We cant share client data without explicit permission per our ISO 17025 QA requirements but Ill reach out and see what they say.

@Vanguard_Lab Are you able to ask the clients to send you picture of the kits and to post the COAs so others with similar kits can be alerted and I'm keeping a record of them too.

Just had a message from Testides lab, Canada. Out of their run of 100 samples, 11 are either mislabelled or zero peps. He's asking the clients to contact me as he can't give out this info without their permission

@Krysia830073 Vanguard has a validated method and reference standard for Elora using LCMSMS / RP-HPLC.

New follow-up on the Elora testing debate. The Elora testing debate shows no sign of slowing down. Despite Janoshik being certain that RP -HPLC and LC-MS are more capable than people initially assumed for Elora testing, not everyone is convinced. Today the debate has now moved into four separate questions: does the expected mass shift actually prove the correct ring formed? is the real risk a missing ring, or a misformed one? can RP-HPLC reliably separate the most structurally similar side products? and will API producers sacrifice yield to purify out low-level misformed species? This is why the Elora discussion keeps getting more complicated. Full article below x.com/Krysia830073/s…

Another Forged COA. Logo is wrong, signatures forged, chromatogram altered, Iso logo not the one we use. Approved by "Teri Johnson" we have a Tori but no Teri's have ever worked at Vanguard...

Endotoxin Testing at Vanguard Laboratory At Vanguard Laboratory, endotoxin contamination is not something we treat lightly. Even trace levels of bacterial endotoxins, specifically lipopolysaccharides from Gram-negative bacteria, can trigger significant immune responses. This includes fever, inflammation, hypotension, and other serious complications, particularly in injectable peptides, biologics, and parenteral products. In immuno-oncology and advanced biologics work, the risk goes beyond safety. Endotoxins can directly interfere with assay performance, leading to false signals, misinterpreted immune activation, and unreliable data. Why Endotoxin Testing Matters Endotoxins are difficult to eliminate and easy to overlook: They are heat-stable and can survive standard sterilization processes They activate immune cells such as monocytes and macrophages They drive cytokine release including TNF-α, IL-6, and IL-1 They can compromise both research outcomes and patient safety This is especially critical for applications involving injectable peptides, biologics, radiopharmaceuticals, cytotoxic agents, and water for injection (WFI). Without proper testing, you are taking on unnecessary risk. How We Approach Endotoxin Testing Our primary platform is the Endosafe® nexgen-MCS, which allows for rapid, quantitative endotoxin detection with high sensitivity and reproducibility. This system supports efficient throughput while maintaining data quality. We also offer additional validated methods depending on project requirements: LAL (Limulus Amebocyte Lysate) Assays The compendial standard, available in gel clot, chromogenic, and turbidimetric formats. Recombinant Factor C (rFC) Assays An animal-free alternative with strong specificity for endotoxins and alignment with current regulatory expectations. Each method is validated based on the sample matrix. We assess recovery, identify inhibition or enhancement effects, and confirm the assay is performing accurately for the specific application. What Our Service Includes Quantitative endotoxin detection with high sensitivity (EU/mL range) Custom protocols tailored to sample type and matrix Integration with peptide and biologic testing, including HPLC purity, potency, heavy metals, and sterility or bioburden Support for depyrogenation validation and process monitoring We test individual samples or full batches with clear, actionable reporting. Turnaround and Quality Our endotoxin testing is performed under ISO 17025-accredited conditions using validated methodologies. Typical turnaround time is 5 to 8 business days, depending on sample type and testing requirements. The Vanguard Standard We do not treat endotoxin testing as a final checkbox. It is built into the workflow from the start. That means: Methods selected based on real sample conditions Validation that accounts for matrix interference Data that holds up under regulatory and scientific scrutiny Bottom Line Whether you are a researcher, clinic, or manufacturer, endotoxin testing is not optional. It is a core requirement for generating reliable data and ensuring product safety. At Vanguard Laboratory, we make sure it is done right.

Endotoxins aren’t something you want to guess on they need to be measured with precision. We run endotoxin testing on the Charles River Endosafe nexgensystem, Widely used across pharma and QC labs for its speed, consistency, and validated accuracy. It’s a true industry standard.

Purity, quantification, endotoxin, & sterility testing of peptides. Samples processed and running 24/7.

The Baby Food Safety Act of 2024 is on the horizon, it's crucial to address toxic metal contamination in baby food. Ensuring safety and vigorous testing, Vanguard Laboratory can help you achieve compliance. Baby Warren is care free knowing his food is free of toxic metals.

We never know what may be lurking inside our mail. These fellows are Darkling beetles, an invasive pest and a scourge to poultry farmers. Vanguard offers Insecticide susceptibility testing of darkling beetle populations, to elucidate the prevalence of resistant populations

@BrianRoemmele Best way to create a personal AI using internal company data and along with pdf files of analytical methods? We have a server full of data, consisting of 1000's of word and excel files and a large library of microbiological and analytical methods/references primarily in pdf

“X’s privacy policy confirms it will use public data to train AI models” Everyone is training an AI model on YOUR data. When will YOU train YOUR AI on YOUR data? Own your own AI, or it will own you. techcrunch.com/2023/09/01/xs-…

Is your family's well water safe to drink? Don't take chances with your health. It's time to test your water! Why Test Well Water? ✅ Detect harmful contaminants ✅ Ensure water quality ✅ Protect your loved ones. Contact us today and take the first step towards peace of mind.

@PaulStamets Beautiful specimen.

Eureka ! A chance encounter with the Prince, Agaricus augustus.

@SCIEXFood Love Sciex instruments, but curious as to what the plan is with the broccoli in the petridish?

Enhanced instrument robustness, ultra-trace level sensitivity, and reduced sample loading. 🔬 Download our technical resources and solutions to meet regulatory requirements. 🌐 sciex.li/afn5rf #NominalMassSpectrometry #FoodTesting #FoodAnalysis #FoodSafety #SCIEXFood

@BioavailableNd @ResilientDad Important to test your water for lead. We see it often in well water and in houses with older pipes. It's an inexpensive test, that could bring peace of mind and prevent exposing developing brains to heavy metal poisoning.

@ResilientDad Would add reduce exposure to lead as link has been shown with ADHD. Cigarettes/cosmetics for mom prior to conception. Painted toys in the mouth for babies.

These along with spending more time outdoors, especially grounded. As well as reducing artificial light and nnEMF exposure indoors.

The more lead people are exposed to in childhood or in the uterus, the more likely they are to engage in criminal behaviour later in life, according to a review of 17 studies #Echobox=1690917295" target="_blank" rel="nofollow noopener">newscientist.com/article/238557…

@newscientist Testing for lead in water is critical. Many older pipes in homes are made with alloys containing lead.