Vuyo Lab

Marine animals are known to be a rich source of fungi with novel properties. We recently sampled anemones, sponges, ascidians and urchins from #gansbaai to isolate fungi that will be used in #tbdrugdiscovery research.

Catching waves 🌊😎

It's amazing to think about all the fascinating sea life 💭, particularly bacteria, and how they may contribute towards developing solutions for public health challenges. #drugdiscovery #drugdevelopment #marinebiology #marinescience #naturalproducts #endTB

🦠🔍 During one of our experiments, we stumbled upon this charming bacterial colony that couldn't resist showing off its best smiley face! Sometimes, even the simplest experiments can lead to the coolest results. So, stay curious, and keep exploring! 😊🧪#MicrobialArtistry

The Oceans - Our future pharmacies Recognizing the value of community engagement, the VuyoLab met with the Kleinbaai community at @MarineDynamics' Marine Evening (06/09/22) to discuss the continued importance of preserving oceans. Read more >> dict.org.za/blog/the-ocean…

Improving treatment of the TB pandemic 🫁 that's ravaging our communities is our goal. Using compounds from #marinefungi in recent study, we used a combination of #metabolomics and #moleculardocking to predict potent #antiTB drugs💊💉of the future. Link: doi.org/10.1016/j.heli…

We agree, #unacceptable ! forgotten #pandemic sun.ac.za/english/Lists/… youtu.be/AC95fKaN4zY

Using biomarkers to predict TB treatment duration (Predict TB): a prospective, randomized, noninferiority, treatment shortening clinical trial gatesopenresearch.org/articles/1-9/v1

#collaborator @VuyoLab SPOTLIGHT: Women in Health: Falling in love with chemistry dailymaverick.co.za/article/2021-0…

Preparation of a #Mycobacteriumtuberculosis related protein and potential inhibitor (ligand) before #moleculardynamicsimulations. #endTB #drugdiscovery

Just posted a photo @ Tygerberg Medical Campus instagram.com/p/CFkVcOwHXBX/…

Just posted a photo @ Tygerberg Medical Campus instagram.com/p/CFkOXd_HNWu/…

"Every antibiotic that is introduced into clinical use has a limited shelf life as it selects for bacteria that have some intrinsic or acquired mechanism of resistance" (Walsh, 2003). Emergence of TB resistance is inevitable, new classes of TB drugs should be discovered.

'New neurons keep developing in the human brain until at least our 90s' researchgate.net/blog/post/new-… via @Primis

@ruvandhi @H37Rvader @FINDdx @StellenboschUni Well done indeed. A very rich repository of discoveries towards TB diagnostics. A new exciting chapter starts...

1.3 The typical peer review process researcheracademy.elsevier.com/navigating-pee…

#Cannabis has long been used as medicine for centuries, well sometimes, illegally. Ricquelle here will investigate the plant's potential as an anti-TB drug candidate using some novel experiments. We promised @SuMBHG and @SUhealthsci not to vaporize the plants 😀🚭

2019 was a long year and for our #yearendfunction we went to @Clay__Cafe and got creative... Come see the painted pottery pieces in #Lab444🤣...Funny how everyone had yellow and purple paint in their artwork😂😂

Our publication!

Explorations in drug discovery have led us to realize that gold mine tailings are actually a rich source of filamentous fungi that produce bioactive compounds. sciencedirect.com/science/articl… #Drugdiscovery, #Naturalproducts,

Our colleague, Dr Liezel Smith, representing the Centre of Excellence for Biomedical TB Research at the first official @NRF_News CoE Science Engagament Seminar hosted by SciSTIP and SciCOM at CREST. @dsigovza @NRF_SAASTA @SUhealthsci @StellenboschUni