Min WU

We were working on this the day before the first covid lockdown in Singapore. 😷

A decade in the making! Bringing together multiple generations across three countries and time zones. Easily the most meaningful and fun project I’ve ever worked on.

@cheesan_tong 😂

@danieldamineli Thank you ! look forward to it ~

@WUMIN_LAB It looks absolutely fantastic Min Wu, I'm glad it's out in such a stunning form! Unfortunately I won't be at the EMBL next week to discuss with you, but my colleagues will.

Calcium oscillations are one of the most universal signals in biology. Yet we still know surprisingly little about how these periodic (or aperiodic) events arise. Happy to present our lab's latest work: doi.org/10.1098/rsob.2…

Fast forward a few decades: tremendous progress has been made in biology. One conceptual hurdle is that the control of calcium oscillations (or action potentials) is not about the spikes (ion fluxes), but the phases in between (chemistry, geometry, etc).

Reading this excellent memoriam, i then realize the phosphoinositides field predates the calcium field, so when they were young, they were the rebels that challenge the dogma of their time, and now, their models became the dogma doi.org/10.1016/j.ceca…

Check out this recently published paper in LSA: F-Actin organization excludes E-cadherin from the division furrow to ensure cytokinesis fidelity @anups_11 ➡️ hubs.la/Q045Rw3C0

@Qivshi1 No such thing . Only older and wiser😊

@WUMIN_LAB Too old

if i was going into cell biology i would focus on brain lipid metabolism, there is a very precise multicellular mechanism going on there that is not currently known, and that will link to a lot of brain disease

人工細胞を利用した細胞内反応拡散波研究に関する総説 生細胞の複雑な内因性因子を除いて系を単純化することで、細菌細胞内で局在を交互に切り替えて分裂面を調節するMin波の詳細な解析がされた例や、この実験系において残された課題などが紹介されている #BNTNJC jstage.jst.go.jp/article/biophy…

@HUST_NengWan Neng u can’t be in Tom’s lab without reading his most important paper (Heinrich and Rapoport, 1973). molbiolcell.org/doi/10.1091/mb… after reading it u will understand waves 😉

@WUMIN_LAB Congratulations! Although I have never understood the “waves@….

Wu Lab: exporting talent to Europe since 20XX.

I have always found #phosphoinositide metabolism difficult to understand, but XJ communicates it so well for people to grasp! Seriously! pnas.org/doi/abs/10.107… In short, PI4P dynamics does regulate PI(45)P2, which in turn would modulate Cdc42-mediated #actin polymerization