Min WU

Ani Michaud, @GoryachevAndrew, von Dassow, @BementLab et al. identify a versatile cortical pattern-forming circuit based on #Rho, F-#actin, Ect2, and RGA-3/4: hubs.la/Q04p9X4Y0 📕 Part of “Collective Behaviors and Self-Organization in Cells”: hubs.la/Q04p9ZLw0

This collection was curated by JCB Editorial Board member Min Wu and Scientific Editor Gabriele Stephan. Blending aspects of mechanobiology, developmental biology, and signaling, we hope this collection will engage a broad readership interested in biophysics and systems biology!

This collection explores emergent phenomena incl. how cellular events are rapidly coordinated by waves of chemical & electrical signals, how tissue patterning is governed at the cellular level & how cellular interfaces guide cellular migration & morphology hubs.la/Q04p9r3T0

Introduced by Bernhard Riemann in the mid-19th century, manifolds are crucial to our understanding of the universe. quantamagazine.org/what-is-a-mani…

@yujin_bao @bewersdorflab This work would not have been possible without the creativity of postdoc extraordinaire Sarah Fung

Perturbing PI(3,4)P₂ degradation increases spindle microtubule density, and causes spindle overscaling relative to cell size. Thanks to @yujin_bao in the @bewersdorflab for characterizing MT density in monopolar spindle by superresolution imaging. 7/n

Excited to share our latest work: Mitotic Cdc42 waves encode PI(3,4)P2 signaling and Golgi morphological state to control spindle scaling | Science Advances science.org/doi/10.1126/sc…

Super excited to share this paper from @O_Farrell_Aoife!

#DynamicsClub in June: 𝗠𝗮𝗿𝗸 𝗚𝗿𝗲𝗲𝗻𝘄𝗼𝗼𝗱 will share his work with Pulin Li on epinephrine dynamics in stress response. June 25 (Thursday) at 11am PT / 2pm ET Join us on Zoom: lingyunxiong.github.io/DynamicsClub/

Reinisch's lab work with @LabVanni, now is online in Cell!! Combining cryoEM and MD simulations, we reveal how the bridge-like lipid-transfer protein VPS13A coordinates with the scramblase XK to deliver and redistribute lipids to plasma membrane. cell.com/cell/fulltext/…

𝗕𝗿𝗮𝗶𝗻 𝗮𝘁𝘁𝗿𝗮𝗰𝘁𝗼𝗿 𝗱𝘆𝗻𝗮𝗺𝗶𝗰𝘀 Does it support a modular and hierarchical organization as the author support? Not really. Highly distributed and multifunctional findings even in the context of a binary task! doi.org/10.1038/s41586…

Sleep may synchronize the brain and body in ways that protect against dementia. During sleep, norepinephrine, dopamine, serotonin, and acetylcholine oscillate together in ~50-second rhythms that help drive cerebrospinal fluid flow and glymphatic clearance of amyloid-β and tau. #SleepScience #Neuroscience #Dementia science.org/doi/10.1126/sc…

this isn’t an abstract concept; your heartbeat is a stable limit cycle sciencedirect.com/science/articl…

An interesting phenomenon in dynamical systems is the limit cycle. A limit cycle is an isolated periodic trajectory, often taking form as a self-sustaining oscillation, where a system’s state follows a closed path and repeatedly returns to the same values.

@alec_helbling dynamical systems have so many more cool properties if you go from strict periodicity to allowing for things that are only kind of periodic en.wikipedia.org/wiki/Attractor