Xiaoyin Chen

25 posts

Xiaoyin Chen

Xiaoyin Chen

@XiaoyinChenLab

Neuroscientist at Allen Institute. BARseq. In situ sequencing. Barcoded Connectomics

Seattle, WA Katılım Ekim 2023
32 Takip Edilen206 Takipçiler
Xiaoyin Chen retweetledi
NIH Common Fund
NIH Common Fund@NIH_CommonFund·
Check out an article published by #NIHHighRisk Research Program #NewInnovator awardee Xiaoyin Chen and his colleagues that sheds light on how vision influences the organization of cells within the brain!
allen institute@AllenInstitute

Vision plays a key role in the developing human brain. 👀🧠 New @Nature study finds that a loss of sight led to major reorganization of brain cell types within the visual regions and across half of cortex. alleninstitute.org/news/how-visio…

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Xiaoyin Chen retweetledi
Reto B. Cola 🦋 @colarb.bsky.social
Reto B. Cola 🦋 @colarb.bsky.social@RBC_ola·
The 2023 CSHL high-throuput neuroanatomy course was a blast! Awesome speakers, organizers, TAs, and a great group of students. Returning back home with lots of new ideas 🧫💉🔬
Reto B. Cola 🦋 @colarb.bsky.social tweet mediaReto B. Cola 🦋 @colarb.bsky.social tweet mediaReto B. Cola 🦋 @colarb.bsky.social tweet mediaReto B. Cola 🦋 @colarb.bsky.social tweet media
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Xiaoyin Chen
Xiaoyin Chen@XiaoyinChenLab·
@TonyZador @KanoldLab @JesseAGillis Our study also shows that BARseq can compare brain-wide gene expression across individuals, because it’s high-throughput, low-cost, and consistent. Imagine applying this to your favorite model/strain/perturbation and see how gene expression changes over the whole brain! 17/17
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Xiaoyin Chen
Xiaoyin Chen@XiaoyinChenLab·
@TonyZador @KanoldLab @JesseAGillis These data suggest that peripheral inputs refine cell type composition of cortical areas largely within a cortical module. Cortical modules are likely established earlier through other mechanisms, and thalamic inputs “push” or “pull” compositional profiles within a module 16/17
Xiaoyin Chen tweet media
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Xiaoyin Chen
Xiaoyin Chen@XiaoyinChenLab·
What makes cortical areas different? We used BARseq to sequence 10.3 million cells across 9 mouse brains in situ. We found that cortical areas have distinct cell type compositions that are shaped by peripheral inputs. biorxiv.org/content/10.110… 1/17
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Keşfet

@TonyZador @JesseAGillis @Nature @leijinmit @ian_wickersham @elonmusk @BarackObama @taylorswift13