Yuka Takemon, PhD (竹門ゆか)

Our latest application of GRETTA is out! We dive deep into the genetic network of a cancer-associated gene and show that several network members can be targeted to kill cancer cells. Huge thanks to everyone who contributed to this work! Especially @mmarra0630 and the POG team.

A new study led by Dr. @mmarra0630 (@ubcmsl @BCCancer_GSC) demonstrates a framework for identifying potential novel treatment targets in cancers driven by the loss of tumour suppressor genes. 💡Read more about the study here: bit.ly/4iFVnqP @UBC @BCCancer @YukaTakemon

Cancer statistics in 2025 🇺🇸- new report 🚨 Cancer is becoming a new disease. We're seeing a fundamental shift in who gets cancer, moving from a predominantly male, elderly disease to one that increasingly affects women and younger people. Key highlights 🧵

Congratulations to my PI @mmarra0630! Honored to be working with you.

Our heartfelt congratulations to our very own Dr. Marco Marra, for this tremendous achievement. We’re so very proud of you. bccrc.ca/articles/dr-ma…

Congratulations to our #CMHFLaureate Marco Marra, PhD for being appointed as an officer of the Order of Canada! 👏👏@UBCMedicine ow.ly/n5mE50UuqH3 ow.ly/pUYY50UuqGX.

What gets erased when you integrate single cell data, and can you recover it? Finally, we know what happens and how to recover the lost signals. So excited to share CellANOVA, published online today in NBT! go.nature.com/4hZnzW5

Another example of the different results one gets from a Scanpy vs. Seurat analysis, in this case a Visium HD dataset from academic.oup.com/bioinformatics… 13 vs. 20 clusters. And qualitatively different results, corroborating what we saw in biorxiv.org/content/10.110…

Why do some patients who get immune checkpoint inhibit develop immune-related myocarditis, which carries a mortality rate of 20-50%? New insights @Nature nature.com/articles/s4158… @sm_blum @MGHCancerCenter @villanilab @MGHMedicine

UMAP was introduced to biology with the claim that it 'preserves the global structure of the data' better than t-SNE. This matters arising article shows that the claimed global structure preservation can be entirely attributed to different choices of initialization. 1/2

4 papers @Nature today on extrachromosomal (ec)DNA and cancer —Present in 17% of cancers —Suppresses the immune response —Prognostic significance (figure) nature.com/articles/s4158… @CharlesSwanton and colleagues

Thrilled to share our paper published in @Nature, where we uncover a new process of tumor initiation through a polyclonal-to-monoclonal transition at the @precancerous stage. So proud of my fantastic team (led by @ZhaolianLu ) and incredible collaborators! nature.com/articles/s4158…

Single-cell biologists, are you looking for a faster way to annotate cells in your scRNA-seq experiments? Try a tool developed by Broad researchers that reduces that task from hours to minutes. Learn more about the Cell Annotation Service, now in beta. broad.io/CAS-News

Free scientific illustrations for biologists! 😍 @NIH has released a library of 500+ free scientific illustrations to create figures, presentations, and illustrations! all freely available in the public domain. Retweet and spread the message! bioart.niaid.nih.gov

Not for the first time, all Nobel Prizes in scientific disciplines this year have been awarded to men

Building pangenome graphs biorxiv.org/content/10.110… github.com/pangenome/pggb

Come visit poster 212 to see how we can computationally predict synthetic lethal interactions to impact precision cancer medicine #AGBTPH

Join us for an evening of #spatialdata analysis with Véronique and Johannes meetup.com/rladies-vancou… #Rstats #Rladies #VancouverEvents #DataScience

@mmarra0630 Thank you, Dr. Marra :)

Congratulations Dr. Takemon!