Anatoli

@nicknorwitz So how much plaque DO you have, doc?

2/2) But let me emphasize this once more: even if I turn out to have very little plaque in my heart, despite what is unequivocally an extremely high lifetime exposure to LDL and ApoB, I am not trying to position myself as a mascot for the idea that "high LDL = good." That's as problematically simplified a statement as "lower is better." I made that clear in yesterday’s letter, here: staycuriousmetabolism.substack.com/p/im-finally-l… My objective is different. It’s to challenge the monomaniacal focus on LDL and ApoB as universal indicators of danger that always necessitate treatment. Whether or not they are part of the causal cascade of atherosclerosis (and they are) the assumption that elevated levels always require intervention is, incorrect. So the core of this discussion isn’t about proving one model universally right or wrong. It’s about thinking critically, embracing nuance, and applying the right tools to the right people. At the end of the day, I’m simply interested in who is willing to engage in a sincere, good-faith discussion. As for those who choose instead to posture or evade, they serve their own kind of utility.

Here’s something odd. Despite the expressed certainty that high LDL is a primary cause driver of atherosclerosis, with claims like “there’s no safe level of high cholesterol” regardless of metabolic state, when I present what seems my own clear-cut case of having a total cholesterol of 700 for nearly 7 years, and then ask a simple question: How much plaque will be in my arteries? Almost nobody guesses: “a lot.” Now, to be clear, this isn’t just a basic coronary artery calcium scan I'm getting. I recently underwent an advanced coronary CT angiography, with expert-guided interpretation and AI-based quantification down to the cubic millimeter (mm3). Of note, people in their 20s and 30s often do show plaque on these scans, including some well-known nutrition influencers. One example that comes to mind is someone in the plant-based community, in his 30s, with a total plaque volume of 61.3 mm³. So I come back to the question: 👉How much plaque will be in my heart? 👉And why does it seem that no one wants to guess “a lot”? These aren’t results I could possibly fake.

@nicknorwitz @grok What’s resistant starch? What food sources are the best for getting them?

@nicknorwitz I thought the APOE3 genotype was about the Alzheimer’s disease 🧐

Today, Telegram notified all its users in Spain with this alert: Pedro Sánchez’s government is pushing dangerous new regulations that threaten your internet freedoms. Announced just yesterday, these measures could turn Spain into a surveillance state under the guise of “protection.” Here’s why they’re a red flag for free speech and privacy: 1. Ban on social media for under-16s with mandatory age verification: This isn’t just about kids—it requires platforms to use strict checks, like needing IDs or biometrics. ⚠️ Danger: It sets a precedent for tracking EVERY user’s identity, eroding anonymity and opening doors to mass data collection. What starts with minors could expand to all, stifling open discourse. 2. Personal and criminal liability for platform executives: If “illegal, hateful, or harmful” content isn’t removed fast enough, bosses face jail. ⚠️ Danger: This will force over-censorship—platforms will delete anything remotely controversial to avoid risks, silencing political dissent, journalism, and everyday opinions. Your voice could be next if it challenges the status quo. 3. Criminalizing algorithm amplification: Amplifying “harmful” content via algorithms becomes a crime. ⚠️ Danger: Governments will dictate what you see, burying opposing views and creating echo chambers controlled by the state. Free exploration of ideas? Gone—replaced by curated propaganda. 4. “Hate and polarization footprint” tracking: Platforms must monitor and report how they “fuel division.” ⚠️ Danger: Vague definitions of “hate” could label criticism of the government as divisive, leading to shutdowns or fines. This can be a tool for suppressing opposition. These aren’t safeguards; they’re steps toward total control. We’ve seen this playbook before—governments weaponizing “safety” to censor critics. On Telegram, we prioritize your privacy and freedom: strong encryption, no backdoors, and resistance to overreach. ✊ Stay vigilant, Spain. Demand transparency and fight for your rights. Share this widely—before it’s too late.

The bureaucracy corrupted democracy

@PeterAttiaMD Nobody’s perfect. Keep doin’ the good stuff, educate people on health-related topics 🍀

The following email is what I sent my team last night. I sent a similar version to my patients, also. *** You’ve put your trust, your credibility, and your hard work into what we have built together, and I take that responsibility seriously. You deserve a complete and honest account of what did and did not happen. I apologize that I did not get this out sooner, but I want to be thorough. The purpose of the DOJ releasing these documents is clear: to identify individuals who participated in criminal activity, enabled it, or witnessed it. I am not in any of those categories, and there is no evidence to the contrary. To be clear: 1. I was not involved in any criminal activity. 2. My interactions with Epstein had nothing to do with his sexual abuse or exploitation of anyone. 3. I was never on his plane, never on his island, and never present at any sex parties. That said, I apologize and regret putting myself in a position where emails, some of them embarrassing, tasteless, and indefensible, are now public, and that is on me. I accept that reality and the humiliation that comes with it. *** I want to start by directly addressing the email thread that I’ve been asked about the most. In June 2015, I sent Epstein an email with the subject line “Got a fresh shipment.” The email contained a photograph of bottles of metformin, a medication I had just received from the pharmacy for my own use. The subject line referred to the picture of the bottles of medication. He replied with the words “me too” and attached a photograph of an adult woman. I responded with crude, tasteless banter. Reading that exchange now is very embarrassing, and I will not defend it. I’m ashamed of myself for everything about this. At the time, I understood this exchange as juvenile, not a reference to anything dark or harmful. At that point in my career, I had little exposure to prominent people, and that level of access was novel to me. Everything about him seemed excessive and exclusive, including the fact that he lived in the largest home in all of Manhattan, owned a Boeing 727, and hosted parties with the most powerful and prominent leaders in business and politics. I treated that access as something to be quiet about rather than discussed freely with others. One line in that exchange, about his life being outrageous and me not being able to tell anyone, is being interpreted as awareness of wrongdoing. That is not how I meant it at all. What I was referring to, poorly and flippantly, was the discretion commanded by those social and professional circles–the idea that you don’t talk about who you meet, the dinners you attend and the power and influence of the people in those settings. What I wrote in that email reads terribly, and I own that. *** I met Epstein in 2014 through a prominent female healthcare leader while I was raising funds for scientific research. At that time, he was widely known in academic and philanthropic circles as a funder of science and moved openly among credible institutions and public figures. Between summer 2014 and spring 2019, I met with him on approximately seven or eight occasions at his New York City home, regarding research studies and to meet others he introduced me to. I never visited his island or ranch, and I never flew on any of his planes. When I was at his home, it was either meeting with him directly, meeting with small groups of scientists, doctors, or business leaders, and once at a dinner in 2015 with a number of guests including prominent heads of state. In retrospect, the presence and credibility of such venerable people in different orbits led me to make assumptions about him that clouded my judgment in ways it shouldn’t have. I was not his doctor, though several times I answered general medical questions and recommended other providers to him. Shortly after we met, I asked him directly about his 2008 conviction. He characterized it as prostitution-related charges. In 2018, I came to learn this was grossly minimized (more on this below). I was incredibly naïve to believe him. I mistook his social acceptance in the eyes of the credible people I saw him with for acceptability, and that was a serious error in my judgment. To be clear, I never witnessed illegal behavior and never saw anyone who appeared underage in his presence. *** In November 2018 I read the Miami Herald investigative article. I was repulsed by what I learned. Nauseated. It marked a clear and irreversible line between what I knew before and what I understood afterward. At that point, I told him directly he needed to accept responsibility for what he did. Hoping to provide the victims from the Herald piece with support, I contacted a residential trauma facility to understand what funding comprehensive care for many victims would require. (Those communications were between me and the facility and were therefore not part of the document release.) I spoke with him and shared that information and insisted that he fund their care, beginning with residential treatment and followed by lifelong therapy. In hindsight, even attempting to facilitate accountability was a mistake and once again reflected just how naïve I was at the time. Once the full scope of his actions was clear, disengagement should have been the only appropriate response. My intent does not change that, and I regret not drawing that boundary immediately. *** Nothing in this letter is meant to minimize the harm suffered by the young women Epstein abused. Their trauma is permanent. I am not asking for a pass from you. I am not asking anyone to ignore the emails or pretend they aren’t ugly. They simply are. The man I am today, roughly ten years later, would not write them and would not associate with Epstein at all. Whatever growth I’ve had over the past decade does not erase the emails I wrote then. I recognize that my actions and words have consequences for the people I care deeply about, including all of you. I regret the cost this has placed on you, and I take responsibility for it. I won’t ask anyone to defend me or explain this on my behalf. If you have questions or concerns, I’ll address them directly with you, my team.

@meduzaproject Чудак какой-то закомплексованный по самые помидоры 🥴

Николай Сторонский объясняет, почему отказался от российского гражданства и излагает свою версию разговора с Тиньковым об инвестициях в Revolut meduza.io/feature/2025/1…

Sorprende (aunque en realidad no sorprende en absoluto) el silencio de los corderos. Y me refiero a periodistas y escritores mudos. La lengua es nuestra herramienta de trabajo. Su libertad, precisión y eficacia son necesarias. Si no la defendemos nosotros, no lo hará nadie.

¡Increíble! Una semana esperando al técnico por la incidencia 215028992 y nadie aparece. Estoy tirando comida por su culpa. Un frigorífico de @HisenseGlobal @hisenseiberiaes roto en menos de 2 años y un servicio así es una #ESTAFA Vergüenza de empresa 👎

@HisenseGlobal @hisenseiberiaes ¡Increíble! Una semana esperando al técnico por la incidencia 215028992 y nadie aparece. Estoy tirando comida por su culpa. Un frigorífico roto en menos de 2 años y un servicio así es una #ESTAFA Vergüenza de empresa 👎

@egtegain @grok es una noticia falsa o no?

🔴SERÉ BREVE. Votación que Modifica el Código penal para condenar a padres y profesionales que se opongan a que menores cambien de sexo, ya sea por cirugía, hormonacion o psicoterapia. SÍ,🟢PSOE, PP, SUMAR, PODEMOS, ERC, PNV, JUNTS, ERC, BILDU, CC,ETC NO🔴VOX ABST🟡UPN

@mjosecatala Un agradecimiento enorme por empezar a resolver el problema de las tiendas! 💪🏻👏 Por favor, no se detenga ahora

El mejor parque de 🇪🇺 está en Valencia. La clasificación mundial de los 10 mejores parques del mundo, otorga la 5ª posición a nuestro Jardín del Turia, siendo el único parque de la Unión Europea de la lista. elmundo.es/como/2025/05/1…

¡Un agradecimiento enorme a @mjosecatala y a la @policialocalvlc por empezar a resolver el problema de las tiendas en el Río! 💪🏻👏 Por favor, no se detengan ahora. La ciudad necesita orden y legalidad para no convertirse en un vertedero…

Reverte: ‘Europa es una porqueria. Está condenada a muerte’. Me alegra mucho coincidir con el maestro @perezreverte aunque creo que veremos su desintegración antes de 15 años. Europa es un banda de chupópteros liberticidas con los días contados.

New episode goes deep into the science of peak athletic performance for the pros and recreational athletes with @DrAndyGalpin. Galpin’s dual expertise as a research scientist investigating nutrition, supplementation, training, and recovery, and as a performance coach working directly with professional athletes and Olympians, informs an integrated understanding of what truly works in practice. In our conversation, we explore how athletes and fitness enthusiasts can effectively balance immediate athletic goals with long-term health, tackling practical questions such as: • Micronutrient optimization (including magnesium, omega-3, and iron) • Fueling strategies around fasted vs. fed training • What truly matters when fueling for performance • Electrolyte management and hydration timing • Recovery techniques addressing inflammation, soreness, and overtraining • Supplement myths and evidence-based recommendations Links to YouTube, Apple Podcasts, and Spotify in the comments. Timestamps: 0:00 - Introduction 2:07 - Eating to perform vs. eating to live longer 5:27 - Training fasted 12:00 - What to eat before morning strength training 13:59 - Nutrient timing 15:50 - Is intermittent fasting killing your gains? 26:31 - Carbs before resistance training 28:14 - Endurance fueling strategies 33:09 - Post-exercise carb intake 34:42 - Game day fueling 37:32 - Carb supplements vs. whole foods 40:25 - Rethinking fat intake 43:21 - Metabolic flexibility 47:46 - The real test of metabolic health 49:02 - Anaerobic vs. aerobic systems 53:03 - Protein timing 55:33 - Whole foods vs. protein powders 1:00:27 - Fat timing 1:01:54 - Seed oils and saturated fat 1:06:49 - Magnesium 1:08:49 - The problem with magnesium blood tests 1:10:07 - Why the magnesium RDA might not be enough 1:11:00 - Magnesium citrate, glycinate, or threonate? 1:13:01 - Magnesium dosing 1:15:40 - Omega-3 supplementation 1:19:16 - Can omega-3s prevent muscle loss? 1:23:20 - "Performance anchors" vs. supplements 1:27:53 - Iron deficiency 1:30:48 - Caffeine before workouts 1:32:35 - Caffeine cycling 1:35:51 - Can music enhance performance? 1:37:03 - Rhodiola rosea 1:41:44 - Nitric oxide boosters (beetroot, citrulline, arginine) 1:52:13 - Beta-alanine 1:58:11 - Creatine 1:59:24 - Sodium bicarbonate 2:01:42 - Pre-workouts 2:04:00 - Does excess caffeine impair performance? 2:04:46 - Antioxidants & high-dose vitamin C 2:12:18 - Anti-inflammatories 2:14:43 - Tart cherry juice 2:18:10 - Glutamine 2:26:17 - Collagen 2:30:32 - Glucosamine chondroitin 2:31:33 - Recovery—signaling vs. inflammation 2:34:31 - The most important recovery metric 2:36:11 - Blood flow for recovery 2:41:01 - Persistent soreness 2:44:08 - Compression boots 2:45:02 - Water immersion 2:48:19 - Sauna vs. extra miles 2:50:18 - Can localized heat preserve muscle? 2:51:37 - Cold water immersion 2:58:22 - Pre-bed cold exposure for sleep 3:01:37 - HRV vs. resting heart rate 3:09:50 - Respiratory rate 3:14:03 - Are you overtrained—or just overreached? 3:18:47 - Hormones and overtraining 3:22:54 - Does training hard increase your sleep need? 3:25:00 - How to know if you're getting enough sleep 3:28:22 - Sleep trackers 3:30:16 - Hydration timing 3:32:00 - Wind-down index 3:33:08 - Bedroom CO₂ buildup 3:36:46 - Nasal allergies 3:38:29 - Sleep hacks

@fmfclips @DrAndyGalpin Gr8 stuff, thanks 🙏🏻👍

Dr. Andy Galpin Shares the Full Nutrition & Supplement Protocol He Gives Pro Athletes Our brand new episode with @DrAndyGalpin Rhonda and Andy discuss: • Recovery tactics • HRV vs. resting heart rate • Nitric oxide boosters (beetroot, citrulline, & arginine) • Rhodiola rosea, tart cherry juice, & beta-alanine • How high bedroom CO₂ sabotages sleep • How to fuel for elite performance And so much more Link in the next tweet

@AjuntamentVLC @bomberosvlc @GVA112 @DevesaAlbufera @GVAparcs @protecivilvlc @VLCVerda @AavvSaler @AssVeinalSaler @AVelpalmar @policialocalvlc @AsociacioP @aeelsaler Solo van a colaborar los que entienden el valenciano 😆 🤦‍♂️

👨‍🚒 Necessitem la col·laboració de tota la ciutadania per protegir la #Devesa. @bomberosvlc ens donen estos consells: 🚭No fumeu 🎇No dispareu artefactes pirotècnics 🚗No bloquegeu els accessos als vehicles ♻️Useu els contenidors adequats 🔥En cas d'incendi, telefoneu al @GVA112

Best health protocol kit for time spent = 1st 90 min of day: hydrate, sunlight (or other bright light if no sun), 1-3min cold*, caffeine, exercise. Last 90min: dim/darken lights, 1-5min physiological sighs (deep nasal inhale, 1 quick addl. inhale, then to-lungs-empty exhale).

@alx LOL, bro 😂🤣

CNN called a they/them a “she”. I can’t stress how offensive this is. People with irregular pronouns have been fighting for dozens of months to be recognized. This sets them back literally weeks. A truly dark day — almost as bad as January 6th.

@AjuntamentVLC @policialocalvlc @ValenciaNetaVLC @CulturalVLC @GHPatrimonioVLC @FedVeinalVLC @CaveCova @FCC_MA @SAV_lavega @GrupoGimeno @tyriusvalencia ¿Habrá algún castigo por vivir bajo un puente o por poner tiendas de campaña en los parques? ¿O es que la policía no lo ve? 🫣

👮‍♂️ Multes de fins a 3.000€ per orinar al carrer, fer pintades en edificis protegits o deixar estris al costat dels contenidors. La #JGL enceta canvis en l'#ordenança de #neteja per pujar les sancions i posar fre a estes i altres conductes incíviques. 🔗 lc.cx/Tl7ZJA