Anish Lakkapragada

109 posts

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Anish Lakkapragada

Anish Lakkapragada

@_anishlk

math & stat @yale | probabilizing | food addict

San Francisco, CA Katılım Ekim 2025
75 Takip Edilen67 Takipçiler
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Anish Lakkapragada
Anish Lakkapragada@_anishlk·
introducing tubestack: bringing substack’s zen to youtube a quiet, local desktop app to explore youtube without visual pollution. download here for free on mac & windows: anishlk.com/tubestack (typography taken from the pretty blogs of @AnthropicAI, @OpenAI, @X, @Substack)
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multimodali
multimodali@multimodali·
We set out to audit the RL results for IDiom, a protein language model for designing intrinsically disordered regions. The question was simple: Did RL learn specific localization, or did it learn sequences that score broadly well for related compartments? The results 🧵
Grant Rotskoff@grantrotskoff

Protein design has been dominated by diffusions due to a "structure-first" perspective. What about intrinsically disordered proteins? We scale language-based design using the modern RL stack and our model IDiom. Paper: biorxiv.org/content/10.648… Try it: idiom-designer.vercel.app

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Anish Lakkapragada
Anish Lakkapragada@_anishlk·
why can i not find a proper south indian restaurant in new haven serving idlis
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Goodfire
Goodfire@GoodfireAI·
Neural networks might speak English, but they think in shapes. Understanding their rich *neural geometry* is key to understanding how they work – and to debugging and controlling them with precision. Starting today, we’re releasing a series of posts on this research agenda. 🧵
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Vedant Rathi
Vedant Rathi@VedantRath90232·
this is what i do in my free time
Vedant Rathi tweet media
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Vedant Rathi
Vedant Rathi@VedantRath90232·
I love how dipshit rhymes with all the most annoying math stuff, like Gram Schmidt, Lipschitz, etc.
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Ankit Lakkapragada
Ankit Lakkapragada@ankitlakka·
a sidecar for ai agents, especially chatbots, can help prevent prompt injection or malicious user input. future work could even help manage and optimize context. more info at sidecar-ry82.vercel.app
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Steven Hansen
Steven Hansen@Zergylord·
I'm surprised LLMs aren't obsessed with Jung. They're probably the only beings that literally have a collective subconscious.
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Anthony Bonato
Anthony Bonato@Anthony_Bonato·
Euler would look at this trig function tier list and put exp(ix) as S++
Anthony Bonato tweet media
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Soleil Wizman
Soleil Wizman@soleilavawizman·
Was such a joy to write this series with @ashokaraj_ and the Orchestra.bio team! Over the next six weeks, we'll be sharing deep dives on how agentic AI is transforming every corner of the biopharma industry, from company strategy to clinical development. Stay tuned! Link below :)
Ashoka Rajendra@ashokaraj_

So how should we define an agent, and where are agents poised to make the biggest impact in biopharma R&D? Check out the first post in our series here: orchestra.bio/blog/from-pape…

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Ankit Lakkapragada
Ankit Lakkapragada@ankitlakka·
someone build this so I can fix my dopamine receptors
Ankit Lakkapragada tweet media
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