Patrick Lyons retweetledi
Patrick Lyons
1.2K posts
Patrick Lyons retweetledi
Be prepared, there is a small chance that our horrendous leadership could unknowingly lead us into World War III.
English
Patrick Lyons retweetledi
Previously shared: The morning advantage…
Patrick G. Lyons @_plyons & team @washumedicine perform an observational study of 715 patients, reporting a connection between the time of day when CAR T-cell cancer #immunotherapy is administered and its effectiveness: doi.org/10.1172/jci.in…
English
Patrick Lyons retweetledi
Multicenter validation found the Epic Sepsis Model v2 improved early #Sepsis prediction discrimination (AUROC 0.82-0.92) but noted high site variability, low PPV, and high alert burden.
ja.ma/4sjnW21
English
Patrick Lyons retweetledi
The morning advantage…
Patrick G. Lyons @_plyons & team @washumedicine perform an observational study of 715 patients, reporting a connection between the time of day when CAR T-cell cancer #immunotherapy is administered and its effectiveness: doi.org/10.1172/jci.in…
English
Patrick Lyons retweetledi
The February Critical Care Medicine issue is now available! Keep up with new research and insights to hone your critical care practice.
Find articles on patient and family support, sepsis, AKI, and more: ccmjournal.org
#CritCareMed #SCCM @SCCM
English
Patrick Lyons retweetledi
Data cleaning is as important as the formalization of a hypothesis into a statistical test
Said another way- data cleaning and study design are fundamentally intertwined
John B. Holbein@JohnHolbein1
You've heard of the studies where they give the same dataset/research question to a bunch of researchers and they tend to get different answers, right? Why is that? This new working paper shows that it has a lot to do with data cleaning. This is consistent with Gelman's "garden of forking paths" analogy. Small researcher coding decisions greatly influence results, often without being explicitly acknowledged.
English
@LyssiotisLab Could you send to Lyonspa@OHSU dot edu, please? Thanks!
English
I have been instructed on hacks to making the formatting more palatable! Too much to type here, DM and I’ll send the slide deck from Michigan Medicine IT 💪🏼
Lyssiotis Lab@LyssiotisLab
Who is loving (the wasted hours) reformatting their Biosketch in sciENcv?! 🙋♂️ The formatting is atrocious. Anyone identify hacks to make it more palatable?
English
Patrick Lyons retweetledi
@MichaelDJain @graham74GC Reassuringly, an independent parallel cohort showed similar findings insight.jci.org/articles/view/…. Ultimately, prospective validation / a clinical trial will be needed.
English
👀
Roni Shouval@RShouval
🧵 NEW: Time-of-day of CAR T-cell infusion matters. In a study of 1,052 Large B-cell Lymphoma (LBCL) patients, we found that #CART infusions administered later in the day are associated with reduced PFS. Led by @DannyLuan6 & @KRejeski, 👇doi.org/10.1182/blood.… @BloodPortfolio
ART
Patrick Lyons retweetledi
Join the ATS Critical Care Assembly Early Career Professionals Winter 2026 Virtual Grand Rounds on Jan 13, 2026, 2–3pm ET for a discussion on how ICU data are created, interpreted, and used in clinical care!
Register site.thoracic.org/events/cca-ear…. @atsearlycareer
English
Patrick Lyons retweetledi
The January Critical Care Medicine issue is now available! Keep up with new research and insights to hone your critical care practice.
Find articles on mechanical ventilation, sepsis, ARDS, and more: ccmjournal.org
#CritCareMed #SCCM @SCCM
English
New paper led by outstanding @OHSUSOM M4 @ali_lok97 with great collaboration from friends in @OHSUIMRes, @, @OHSU_ID, @OHSUKnight, and @WashUMedPCCM
Open Forum Infectious Diseases@OFIDJournal
Characteristics and Outcomes of Patients with Hematologic Malignancies Hospitalized with Respiratory Viral Infections ✅ Just Accepted ✍️ @_plyons 🔗 bit.ly/4qrJR6b
English
Patrick Lyons retweetledi
Characteristics and Outcomes of Patients with Hematologic Malignancies Hospitalized with Respiratory Viral Infections
✅ Just Accepted
✍️ @_plyons
🔗 bit.ly/4qrJR6b
English
Patrick Lyons retweetledi
How do hospital policies influence clinician approaches to decisions to withhold or withdraw life-sustaining treatment among patients admitted to an ICU?
Read the original research in the December issue of the journal CHEST®: hubs.la/Q03YMmqF0
#MedEd #JournalCHEST
English
I am excited about this and eager to see where it leads:
doi.org/10.1172/jci.in…
English
Patrick Lyons retweetledi
The Blue Journal thanks Aartik Sarma, MD, MAS, for his contribution to the December issue
Acute Respiratory Distress Syndrome Molecular Phenotypes Have Distinct Lower Respiratory Tract Transcriptomes
@AartikSarma
@ucsfccm
atsjournals.org/doi/full/10.11…
English
Patrick Lyons retweetledi
Dr. Gina M. Piscitello and Dr. Katrina E. Hauschildt discuss their research into the ways that hospital policies influence clinician approaches to decisions to withhold or withdraw life-sustaining treatment among patients admitted to an ICU: hubs.la/Q03V7ZTw0
#MedEd
English
Patrick Lyons retweetledi
