Antonio Gallardo-Pizarro

📢Recordamos, V Reunión científica anual de GESITRA-IC @GesitraIC, @SEIMC_ 📅 5-6 de marzo 📍Madrid 📚📝Programa/inscripción 👇 seimc.org/grupos-de-estu…

The AMR Action Subcommittee and Study Group for Artificial intelligence and Digitalisation (ESGAID) recently published a perspective on the implications of using AI in the fight against #AMR. Check it out: ow.ly/Bbwm50YeZTF

Febrile neutropenia still drives heavy carbapenem use due to MDR Gram-negatives. In a cohort of 553 FN episodes, an ML risk model + prior colonisation data could cut meropenem use by ~30% and IEAT from 23% to 9%, supporting personalised EAT. journals.sagepub.com/doi/full/10.11…

Based on expert opinion, national guidelines suggest obtaining 2 sets of blood cultures at the onset of FN and repeating cultures on FN days 2-3. 🆕⚡Retrospective cohort study of patients with hem/onc diagnoses & an FN episode >3d Detection of new BSI after FN day 3 was uncommon, demonstrating low diagnostic yield of repeat blood cultures after FN day 3. In a cohort of >500 patients with persistent FN, new BSI after FN day 3 was identified in 4% of patients and 2% of days with cultures collected. FN onset in the peri-HCT period (day -7 to +30) was associated with 80% lower odds of new BSI after FN day 3. Among new organisms in blood cultures after FN day 3, 26% were contaminants with over half leading to excess vancomycin use, highlighting the importance of diagnostic stewardship in this population. @BradSpellberg @DrToddLee ICYMI #IDXposts academic.oup.com/cid/article/do…

💥#ProudOfMyTeam 🎯New accepted paper! Impact of Novel β-Lactams on Gut Decolonisation in Haematological Patients with Multidrug-Resistant Gram-Negative Infections @sehh_es @SEIMC_ @ESCMID @EHA_Hematology @TheEBMT @hospitalclinic @idibaps sciencedirect.com/science/articl…

💥#ProudOfMyTeam New accepted paper! Congrats @agallardop_ ! Proof of concept: #AI and rectal swabs improves empiric antibiotic selection in febrile neutropenia!! pmc.ncbi.nlm.nih.gov/articles/PMC12… @sehh_es @SEIMC_ @ESCMID @EHA_Hematology @TheEBMT @hospitalclinic @idibaps @CoREIMC_seimc

Tratamiento ambulatorio en pacientes con endocarditis infecciosa: análisis de las estrategias actuales. Marta Maristany @hospitalclinic en #SEICAV25 @IETeamClinicBCN #endocarditis

Gene therapy has long held promise for the treatment of Parkinson’s disease. In @TheLancetNeuro, authors explore clinical trials and technical advances in gene therapy for Parkinson's disease: hubs.li/Q03zZPW-0

⚠️ Brote de gripe H5N1 en granja de pavos en Badajoz.

A brilliant UCLA Hematologist, Dr. Gary Schiller, said something to me when I was a medical student that I didn't understand at the time, but in retrospect, turns out to have had a profound, long-lasting impact on me. Specifically, on how I view the concept of "expertise".

#ProudOfMyTeam 💡📡News published in CMI!! 🔝🔝 Improving knowledge to personalize empiric antibiotic treatments in hematological patients Congrats ⁦@agallardop_⁩ Rectal colonization by MDR GNB and subsequent BSI in haematological patients pubmed.ncbi.nlm.nih.gov/40482885/

#JornadaHematoAvanza25 👉 El trasplante de médula ósea es la #terapia celular más antigua que existe, y con ella se han curado miles de personas. Para ello, es fundamental la #donacion. 📹Te lo explica en este video Montserrat Rovira, del @hospitalclinic y si quieres saber➕, no te pierdas su ponencia completa en nuestro canal de #HemoTube 👉Más allá del cáncer sanguíneo youtube.com/watch?v=fMFaXQ… #HematoAvanza #HematoEnRed #THP #donamedula

Words matter. It’s time to retire the term oral “step-down.” It implies inferiority of the oral route—and doesn’t align with stewardship principles. Terms like IV to oral switch or oral transition better promote optimal antimicrobial stewardship. What terms do you use—and why?

🏥 El #CLÍNIC-@idibaps ha alcanzado un hito histórico con el tratamiento de más de 5️⃣0️⃣0️⃣ pacientes con terapias CAR-T propias. 🧬 Es el único hospital de Europa que ha desarrollado íntegramente dos terapias CAR-T académicas que están aprobadas por una agencia reguladora (AEMPS). 🔬 En la actualidad se están desarrollando nuevos CAR-T para tratar a pacientes con diferentes tipos de tumores sólidos o enfermedades hematológicas. La investigación se centra también en mejorar la funcionalidad de los CAR-T una vez llegan al tumor. 👉 f.mtr.cool/tvxpmtbipi

Qué es el SITRAME? Nuevo síndrome autoinflamatorio descrito en adultos. Atentos a las características: semejan celulitis recurrentes sobre todo en tronco con fiebre #SCAEDV #Dermatologia

Ya no se trata solo de elegir el antibiótico. En neutropenia febril, el cambio es de estrategia. IA y decisiones que importan. Nos vemos en Cartagena! 🦾 @Area2Cartagena

When meta-analysis fails to show statistically significant difference people claim there is none. Not true. When meta-analyzing non inferiority trials, you don't expect one! Here we apply the concept of an NI meta analysis to duration of abx for GNR BSI jamanetwork.com/journals/jaman…

Arrancamos el #XVICongresoNacionaldeMicologia con una mesa sobre Epidemiologia y diagnóstico 👏🏻👏🏻👏🏻⁦@AEMMicologia⁩ ⁦@gemicomed⁩ ⁦@Ana_Alastruey⁩

👀 Quantifying potential immortal time bias in observational studies in acute severe infection academic.oup.com/ofid/article/d…

Effects of cancer therapy on AMR Cisplatin➡️cross-resistance to FQ (target bacterial DNA) Methotrexate➡️dihydrofolate reductase mutations➡️co-select for β-lactams/AG/fosfo resistance Anthracyclines➡️efflux pump expression Etoposide➡️oxidative stress➡️gyrA mutations doi.org/10.1016/j.lanm…