Alan Yin

@wolfeagle1989 Thanks for the update! Really appreciate you getting Collection 42 caught up. Good to know the BA.3.2 descendants are in there now. And yeah, I can imagine pruning and upkeep have gotten a lot harder with the GISAID data withdrawn...

@alanyinjs @alanyinjs FYI I have gotten caught up on Collection 42. The larger Collection 24, which is too big for most people’s machines but which I use to help manage Collection 42, is updated but still needs pruning.

I’ve also seen John Cornyn and Greg Abbott try to attack James Talarico like this. If this is the best attack Republicans can find against Talarico, Texas is likely flipping Blue. And expect Democratic strategists to take notice.

@wolfeagle1989 I was trying to run a quick relative growth advantage ranking and noticed that BA.3.2 descendants (e.g. RE.2.2) could serve as the baseline, but they don’t appear to be included in the ranking.

@wolfeagle1989 Hey @wolfeagle1989 quick question: I noticed that none of the BA.3.2 descendants were included in Collection #24. Do you know why that is?

@michael_hoerger Hi Dr. Hoerger - do you have a link/source for the CDC update you're referring to (the Aug 2025 revision that increased the estimate for the winter 2024–25 wave)? I was only able to find this CDC page, but I don't see that specific update mentioned: cdc.gov/covid/php/surv…

These 2025 estimates are subject to retroactive corrections, which are often quite substantial. In August 2025, for example, the CDC substantially increased their estimate of the winter 2024-25 wave.

PMC estimates 260 million SARS-CoV-2 infections in the U.S. in 2025. This is 76% of the population, minus within-year repeat infections. This would mean 13-52 million new #LongCOVID conditions, assuming 5-20% per infection. We estimate 81-175 thousand plausible excess deaths.

@michael_hoerger Hi Dr. Hoerger! Do you have a link/source for the CDC update you're referring to (the August 2025 revision that increased the estimate for the winter 2024–25 wave)? I was only able to find this CDC page, but I don't see that specific update mentioned: cdc.gov/covid/php/surv…

@michael_hoerger @BuDs_UK Hi Mike! Quick question — did they recently take down the site-specific numbers and trends from the CDC website? And is it still possible to access the raw data for a specific testing site somewhere?

@BuDs_UK How can you help? 🔥Share, translate, and add commentary to what I have posted for your nearby dashboard. 🔥Provide your own updates weekly or monthly about your nearby dashboard. 🔥Let me know what dashboards I have missed, so I can review and add them. 🧵 41/

🌍Want to track COVID transmission accurately worldwide? This PMC thread walks you through leading dashboards with information more up to date than WHO & EU directories. 🧵 1/

@zhouliang_mask Hi Zhou! We really like your spring flower masks, particularly since the standard ONE masks don’t come in a size S. Do you plan to produce ONE masks in small size soon? We’d be very interested in placing another order! We’re also open to placing a bulk custom order.

The black snake pattern version of Zimi ONE has been discontinued, with approximately 500 pieces in stock (including the filter). The spring flower mask of Zimi ONE has been discontinued, with approximately 700 pieces in stock.

@zhouliang_mask Hi Zhou! We really like your spring flower masks, particularly since the standard ONE masks don’t come in a size S. Do you plan to produce ONE masks in small size soon? We’d be very interested in placing another order! We’re also open to placing a bulk custom order.

Mask disinfection experiment using hypochlorous acid. We did a similar experiment 2 years ago. Last time, 100ppm hypochlorous acid was sprayed on the inner and outer surfaces of the mask, and the initial filtration efficiency of the mask was tested at 85LPM after drying. No significant decrease in the initial filtration efficiency of the mask was found. This time, the mask was soaked in hypochlorous acid disinfectant with a content of 100mg/L-130mg/L for 1 hour. After air drying for 20 hours, it was tested using TSI PortaCount mask quantitative equipment. The FIT score of the new mask was 154, and the FIT score after hypochlorous acid treatment was 149. The fit of the mask after hypochlorous acid soaking and drying did not change much. Hypochlorous acid disinfectant has strong corrosion on the metal test pins of the mask. Even after drying for 20 hours, there is still a smell of disinfectant in the mask. There are usually three types of standard tests for mask tightness: GB2626/EN149 leakage: Check the tightness of the mask structure in a high-concentration particulate environment. GB19083-2010/NIOSH N95 FIT: Check the mask structure fit ability through low-concentration particulate matter daily environment. NIOSH N99 FIT: Check the mask structure fit ability + mask filtration ability through low-concentration particulate matter daily environment. The above is my own test, using the N99 full particle size mode test in the TSI PortaCount device. , if you encounter questions about masks, you can get the answers you want through objective testing equipment.

@TripWorryf503 @JeromeAdamsMD Just out of curiosity: when did you get your most recent booster?

@JeromeAdamsMD Hi Dr Adams. I was able to use API and bypass my denier MD here in the US. I had the blood drawn at a Quest lab. Also, Labcorp will allow you to self order a much better (up to 25,000) antibody count. These are my recent results.

With Covid vaccine updates now approved, millions are wondering when to get the shot after their recent infections. While not variant-specific, antibody testing can still provide valuable information. I used a prototype home test, but sadly they are not available to the public.😞

@inkblue01 What's even worse: The data came from China, where for most individuals, their first infection was with Omicron in late 2022, and 90% of the population was fully vaccinated (and boosted) before their first infection.

I don't think I've seen this before. #LongCovid symptoms are more severe upon the third and fourth infection. Just look at fatigue and memory decline. 😭 thelancet.com/journals/lanwp…

@zalaly @qldhealth @Mark_Butler_MP dailymail.co.uk/news/article-1… Shame on all of you @AlboMP

@zalaly Meanwhile, the CHO of Queensland, Australia denies the existence of long COVID, citing it's "almost identical to other post-viral conditions". Given his track record with public health failures, it’s baffling why he's still in the position. @qldhealth @Mark_Butler_MP

🚨 Long COVID is a significant health crisis in China too! My commentary on the largest Chinese study to date, involving 74,075 participants, which found that 10-30% of them reported long COVID symptoms such as fatigue and brain fog #LongCovid thelancet.com/journals/lanwp…

@Mike_Honey_ @dj1au @zalaly John Gerrard, the CHO for Queensland is way worse: dailymail.co.uk/news/article-1…

@dj1au @zalaly I keep forgetting: is it the COVID inquiry is coming out and then he is retiring abruptly? Or the other way around?

@TRyanGregory @Tara2911 The thing that baffles me is that 4.5 years into the pandemic, we’re still yet to see any lineage that demonstrates a significant decrease in virulence. Not even one that's co-circulating...

@Tara2911 The most virulent lineage went extinct at the time thanks to herd immunity (which doesn't happen for SARS-CoV-2) but descendants of other lineages do remain today.

Again, the 1918 flu pandemic is a terrible model for the SARS-CoV-2 pandemic.

@TRyanGregory @Tara2911 It seems that even if there were long lasting herd immunity against earlier variants like WT, Delta, Lambda, and Mu, stopping them from circulating, the less virulent Omicron variant is still too virulent to be considered "seasonal" or "mild".

@TRyanGregory @Tara2911 Just out of curiosity: Is there even a less virulent lineage for SARS-CoV-2 comparable to the current circulating lineages of seasonal influenza?

@TRyanGregory @RajlabN @LongDesertTrain @arijitchakrav @mike_honey @JPWeiland @JosetteSchoenma @SolidEvidence @siamosolocani @EmilyAnne_Smith There should also be a post on who we should not listen to: e.g. Monica Gandhi, Leana Wen, Bob Wachter, Sunetra Gupta… and the list goes on…

Writing about SARS-CoV-2 in 2024? Pro tips: 1. Stop platforming always-wrong minimizers. 2. Talk to folks who have been right consistently: @RajlabN @LongDesertTrain @arijitchakrav @Mike_Honey @JPWeiland @JosetteSchoenma @SolidEvidence @siamosolocani @EmilyAnne_Smith 1/

@TRyanGregory @RajlabN @LongDesertTrain @arijitchakrav @mike_honey @JPWeiland @JosetteSchoenma @SolidEvidence @siamosolocani @EmilyAnne_Smith I remember there used to be a website documenting Leana Wen's track record of minimising Covid and being wrong. Does anyone still have the link?

@cyntiadkins @Friesein 1195 Boblett St, Blaine, WA 98230

Novavax Availability Update 📢 QFC Pharmacy in Bellevue, WA was reportedly administering Novavax JN.1 as of today (September 12, 2024). Unlike CVS, they ordered at least two boxes of 10 doses. Appointments must be booked online. Booking link in next post.