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Let's talk about Epitalon.
A deeper dive into the heart of the cell.
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BioRegulator
461 posts
BioRegulator
@BioReg
Bioregulators & Decoding Thymus & Mitochondria
Katılım Ocak 2026
81 Takip Edilen3K Takipçiler
Because Epitalon comes from the pineal peptide line, and the pineal gland is more than just sleep. It is deeply tied to
- immune timing
- thymus aging
- endocrine rhythm
- stress adaptation
- circadian organization
- retina-light signaling
- broader neuroendocrine coordination.
BioRegulator@BioReg
Another side of Epitalon that deserves more attention is the immune timing and recovery. Khavinson's research shows Epitalon may help re-coordinate the pineal-thymus-bone-marrow network, supporting T-cell function, cytokine balance, and recovery under severe stress. This is helping weakened immunse systems get back on in synch.
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@AsafBartov That's a great question and unfortunately I don't have a good answer for you right now.
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Another side of Epitalon that deserves more attention is the immune timing and recovery.
Khavinson's research shows Epitalon may help re-coordinate the pineal-thymus-bone-marrow network, supporting T-cell function, cytokine balance, and recovery under severe stress.
This is helping weakened immunse systems get back on in synch.
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@BlomquistOlle I personally have never taken nasal spray but Khavinson did patent a nasal spray for method of use.
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@BioReg If taken via nasal spray, would all these benefits still be expected? Thanks :)
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@Zedzies What would best to eat in the morning? Occasionally I would eat protein in the morning but recently I've switched to just eating fruits.
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@AgarthaSid Yeah great info on that - It's amazing to see how these all work together.
There's actually a study on the pineal and thymus peptide for longevity pubmed.ncbi.nlm.nih.gov/14523363/
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@BioReg Just started looking into this after finding a lead.
There’s a paper out there.
Suspect that thymalin and epitalon work way better together than in isolation (way better than sum of parts?), by repairing the pineal-thymus axis which seems to decay together.
Sid@AgarthaSid
So there is a research paper on this already. Had no idea. Maybe a good annual system could entail: 1) repairing the gut for a period 2) repair pineal and thymus together for a period 3) Otherwise be free and use more androgenic/nootropic compounds to push the envelope
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@BioReg Would be nice for a community spreadsheet of sorts - to start seeing how long perceived effects last whilst off, for example.
Generally before bioregulators became big this last half year the advice was a certain period on (loading dose) and then back on for 10 days/month
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Epitalon is bigger than melatonin or telomeres.
Helping underperforming aging systems move back toward a healthy baseline.
That’s why bioregulators matter.
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Working on a free video to go along with this if you guys want a shorter less technical version
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New substack: Really good study here on the effects of Pinealon on athletes.
substacktools.com/sharex/HpmCJzN1
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@BowerPower007 @AbudBakri Id suggest keep taking it - sometimes it takes a bit to build up.
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@BowerPower007 @AbudBakri More context? Oral or subq and how much?
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@BioReg @AbudBakri Brother I took Pinealon yesterday morning for the first time and felt nothing, maybe I should try taking it later in the day?
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@MindOfIntra @AbudBakri Yeah I was doing that too I noticed a difference as well - I’m running 1 - 2 mg a day for about a month and then take a couple weeks off.
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@BioReg @AbudBakri wild
ive been testing how I feel when I stay up late and get less sleep and I definitely notice a positive difference, and I’m running 1.5mg 3x a week, doses are always between 9am-12pm
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And pinealon changes brain metabolism...would you look at that...
PPARa, PPARg, Irisin, GDF11, Casp3, SOD2
Sam Empie@sam_empie
Ray Peat often spoke about the vividness of one’s dreams as being a good sign of metabolism levels
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I had a question about that - when they first gave the wrestlers a max dose (I couldn’t find the exact dosage) of pinealon within 3-5 days the 5 wrestlers had higher BP and HR and headaches. So they went back to the drawing board and came up with a 15 day protocol and gave them 100 mcg.
Was there body just overstimulated with the original dosage? M
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@BioReg that study solidifies how pinealon has to be part of any athletic stack. Working on bringing this to the Enhanced Games
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First night. DEEP longer than my usual which is often 45-60m. I’m wearing the tracker this week. And I’ll see if last night was an outlier. Can’t make too much of one night. But it did raise my eyebrows this morning.
CoffeeBlackMD@CoffeeBlackMD
Starts today. 2 caps in the AM on the empty stomach per @AbudBakri (🙏🙏). I’ll be wearing my watch at night for this week so we can see if the sleep tracker shows any valuable data.
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