Boris Hejblum (@borishej.bsky.social)

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Boris Hejblum (@borishej.bsky.social)

Boris Hejblum (@borishej.bsky.social)

@borishej

INSERM Researcher in biostatistics & #rstats enthusiast - views are my own

Katılım Haziran 2012
565 Takip Edilen292 Takipçiler
Boris Hejblum (@borishej.bsky.social) retweetledi
Sarah Lotspeich (She/Her)
Sarah Lotspeich (She/Her)@SarahLotspeich·
🌎 Excited to be heading to beautiful Portugal for my first International Symposium on Nonparametric Statistics! I'll be talking alongside @borishej, Yanyuan Ma, and @mslaylap about nonparametric methods to take advantage of auxiliary data in health settings! 🏥
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Boris Hejblum (@borishej.bsky.social) retweetledi
Mark
Mark@Sanbomics·
RNAseq counting tools are not perfect. I simulated 240 GTEx samples to test multiple tools. Below I show the difference between actual and estimated counts for each simulated sample. But, what is causing this? And will it affect differential expression? (1/7) #Bioinformatics
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Lior Pachter
Lior Pachter@lpachter·
What is happening in single-cell genomics?! A new paper from the Karasuyama lab at @TMDUniversity (nature.com/articles/s4146…) shows three different RNA velocity / pseudotime plots, no pair of which agree, and then merrily goes on to tell some story. 👀
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Boris Hejblum (@borishej.bsky.social) retweetledi
Lior Pachter
Lior Pachter@lpachter·
In a recent preprint with @GorinGennady (biorxiv.org/content/10.110…) we provide a quantitative answer to to this question, namely what information about variance (among cells in a cell type, or more generally many cell types) does a UMAP provide? A short🧵1/
Wallace Marshall@WallaceUcsf

has anyone published a single-cell RNAseq atlas of a single cell type, like budding yeast or RPE1 cells, and made a u-map type plot? does it look like a nice compact sphere or something, or does it show a higher complexity? i know I should know but...i don't.

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𝕐
𝕐@nomad421·
The number of single-cell RNA-seq studies with analyses based on the closed-source CellRanger (>=3) counting/quantification tool is truly astounding and quite depressing given the number (and quality) of the available open-source and transparent alternatives 😪...
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Lucy D’Agostino McGowan
Lucy D’Agostino McGowan@LucyStats·
🎙️ On this weeks episode we talk about a “Causal Quartet” a set of four datasets generated under different mechanisms, all with the same statistical summaries (including visualizations!) but different true causal effects (Plus a chat about M-bias!)
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Casual Inference Podcast@casualinfer

M-Bias: Much Ado About Nothing? | Season 4 Episode 10 casualinfer.libsyn.com/m-bias-much-ad…

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Boris Hejblum (@borishej.bsky.social) retweetledi
Anne-Laure Boulesteix
Anne-Laure Boulesteix@BoulesteixLaure·
Follow-up thread on potential approaches by our group and many others towards addressing the REPLICATION CRISIS IN METHODOLIGAL/COMPUTATIONAL SCIENCE discussed in twitter.com/BoulesteixLaur… 1/n
Anne-Laure Boulesteix@BoulesteixLaure

A replication crisis in methodological computational/statistical research ? I have now been working on the topic for 13 years with my group and it is time for a (long) thread. First, let me say this is not about the replication crisis in application fields of statistics. 1/n

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Amy Willis 😻 amydwillis.bsky.social
Amy Willis 😻 amydwillis.bsky.social@AmyDWillis·
Thinking of submitting to @GenomeBiology? Is it work you're really excited about? My advice? Don't! Here's an email I sent a week ago: no reply. "Previous correspondence" = 5 polite enquires spread over >250 days. I hope peer review is going better for you all 💚💙
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Boris Hejblum (@borishej.bsky.social) retweetledi
Maarten van Smeden
Maarten van Smeden@MaartenvSmeden·
It is silly to try to separate data analytical methods into machine learning, AI and statistics. They cannot be separated from a historical point of view, from how they are used, for what they are used and by whom they are used
Zainab@Syyeda14

Tell me your controversial opinions

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Keşfet

@mslaylap @BPH_Research @Isped_Bordeaux @RodThiebaut @TMDUniversity @GorinGennady @InstMathStat @sabineIk11