Bryan Neth, MD, PhD

What is the long term control Sporadic Vestibular Schwannoma after radiosurgery? LC 5, 10, & 15 years 96%, 92%, & 91% 13% pseudoprogression median time 0.5 yrs (only 4% >5yr after SRS) doi.org/10.3171/2025.8…

For decades, researchers have noted that cancer and Alzheimer’s disease are rarely found in the same person go.nature.com/4qIHwo2

Gonzalez-Aponte et al. reported circadian rhythms in MGMT promoter methylation and protein levels in GBM, with peaks at midday and CT4, respectively, predicting time-of-day differences in temozolomide efficacy. #JNO Read more:link.springer.com/article/10.100…

Also this came out today! newsnetwork.mayoclinic.org/discussion/may…

Cognitive recovery after radiation brain mets meta-analysis · 1/3 cognitive recovery @6mo after initial decline · Recovery more likely if SRS or HA-WBRT compared to WBRT academic.oup.com/jnci/article-a…

A decade after our world-first BBB opening for #GBM, our newest trial shows FUS is safe, well-tolerated, with signals of benefit. A major milestone for a devastating illness. Grateful to @INSIGHTEC, @FUSFoundation, our donors, and brave patients. sciencedirect.com/science/articl…

Coming soon, our first ever issue dedicated to…

Longevity science has hit the mainstream—but no one agrees on the science wsj.com/health/wellnes…

This is a great description of what is was like for ⁦@BobbyMukkamala⁩, incoming AMA President and ENT surgeon, to have an awake craniotomy. ⁦@MayoClinicNeuro⁩ ⁦@MayoClinic⁩ podcasts.apple.com/us/podcast/cha…

When I have a new fellow or resident in our peripheral nerve clinic, I always teach them the importance of defining the neuropathy clinical syndrome. NCS/EMG are valuable, but the neurological exam is the most important (as it should be in neurology but many have forgotten). This is the neuropathy clinical phenotype classification I find the most helpful: - Isolated small fiber neuropathy - Length-dependent peripheral neuropathy (or distal symmetric polyneuropathy) - Multiple mononeuropathies - Mononeuropathy - Asymmetric neuropathy - Polyradiculoneuropathy - Plexopathy (brachial or lumbosacral, many times a radiculoplexus neuropathy) - Sensory neuronopathy - Motor neuronopathy I always tell my trainees they don’t have to memorize the causes of each phenotype. If you define the syndrome correctly, you can ask Google or ChatGtp what are the most likely causes. 😊 Definitions 👇👇👇 #NeuropathyBites 1/x

Our new CASPR2 paper is out @ANA_journals 🤩 Headlines: Patients have neuropathic pain & fatigue as their main long term complaints which determine QoL. 😰 These are NOT immunotherapy responsive. 👩🏾‍⚕️💊 We also report other nuggets in this thread 🧵 ⬇️ onlinelibrary.wiley.com/doi/10.1002/an…

In celebration of the legendary career of Professor Peter J. Dyck, who officially retired last month, I kick off today this series with a hidden gem: The 10 P's in the characterization and differential diagnosis of peripheral neuropathy. #NeuropathyClassics #DyckPapers 1/

Instead of listing my publications, as the year draws to an end, I want to put pressure on the commonplace assumption that productivity must always increase. Good research is disruptive and thinking time is central to high quality scholarship and necessary for disruptive research

Dementia is at the crossroads of prediction and prevention of neurologic disease. Whether we define AD clinically or biologically, robust predictive biomarkers will be central to the care of these patients My editor’s preface from our latest Continuum issue on Dementia ⬇️

Delighted to share @dinoto_ale et al study on the rare cerebellar attacks in #NMOSD attacks: ➡️ Often coexist with brainstem attacks ➡️ MRIs with peduncle or dentate nucleus lesions ➡️ Should be incorporated in upcoming 2025 #NMOSD diagnostic criteria 👇 neurology.org/doi/10.1212/NX…

Honored to speak w/ @mariashriver on the @TODAYshow to discuss how AI is revolutionizing early detection of Alzheimer's. Watch the full conversation here: youtube.com/watch?v=9Mczus… @NaipMayo @MayoClinicNeuro #AI #BrainHealth

1/ This is the next chapter of a story about courageous patients and their families, of multidisciplinary teamwork, and hard-fought steps forward to effective therapy for #DIPG #DMG, a universally lethal cancer of the brain and spinal cord. 🧵nature.com/articles/s4158…

Fastigial Nucleus: the most important structure you’ve never heard of. 6 points on anatomy and function.

To advance any field you must be open to the perspectives/knowledge of others - especially if this is contrary to prevailing dogma. Brain Fables buff.ly/3V7ozLK

Inhibition of IL-11 signalling extends mammalian healthspan and lifespan | Nature nature.com/articles/s4158…