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Matt Daniels MD PhD
17.9K posts
Matt Daniels MD PhD
@cardiacpolymath
International Medical Director Stem Cell Development|Academic Cardiologist (ACHD&ICC)|Ex@SCAIelm chair| @CambridgeMBPhD alum|@steelershockey fan|Dad/Husband/Son
Boston, MA Katılım Kasım 2016
525 Takip Edilen3K Takipçiler
@MarkUkLeaf We had the collywobbles but all lines had brief periods of dominance
Their goalie looked beatable, but I don't see us scoring 6 a game at this level
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@JohnSimpsonNews He looks like he's having a good time too
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Not sure he gets the accent quite right, but he’s doing wonders for Japan’s image in the UK. I’ve watched loads of ambassadors over the years, many of them (though fortunately not all) bores or time-servers. Hiroshi Suzuki is the complete opposite — a real star!
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@pknoepfler Whatever it is, it's not making the job of drug development smoother
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Uh, who will be left? Is this a purge or a bunch of people finally just having had enough?
Adam Feuerstein ✡️@adamfeuerstein
UPDATE: Katherine Szarama, acting CBER chief, also out. FDA drug center head Tracy Beth Høeg leaves as agency faces leadership vacuum statnews.com/2026/05/15/fda… via @statnews
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Matt Daniels MD PhD retweetledi
In Japan, children clean their own schools.
Every day. After lunch.
About twenty minutes.
Classrooms.
Hallways.
Toilets.
Not because the schools are too poor
to hire someone.
Because in 1947, this country decided
that cleaning your own space
is part of becoming a person.
The cleaning rag
is on the school supply list.
Right next to the pencils.
Egypt teaches it now.
So does Indonesia.
So does Mongolia.
Think about the last time
you watched a seven-year-old
mop a floor without complaining.
Japan does that
in every elementary school
in the country.
Not as punishment.
As education.
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@tristonsmithmd @anish_koka I hear some US TAVR programs are struggling with anaesthetic cover (that they want) while encumbered with the cardiac surgeon they haven't needed for a decade
Don't know how true/generalisable this is .... But sometimes the status quo needs to change
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No it’s not. !!!! Service lines are there to streamline care and maximize outcomes for the patients and also for the hospital bottom line. There is zero financial incentive for service lines to push TAVR over SAVR.
Real world Medicare TAVR vs SAVR claims from over 500 programs from Reddy et al showed that the Median contribution margin sits at $11,979 for SAVR versus only $9,076 for TAVR.
Even more telling is that SAVR delivered positive margins in 93% of programs whereas TAVR was only positive in about 68%.
CV service lines have zero financial incentive to keep pushing TAVR over solid surgical AVR. The numbers just don’t support it. Device costs are still eating TAVR alive while surgery keeps the lights on.
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Because of reimbursement, every TAVR requires a CT surgeon to sign off.
Is that just a formality in the age of the heart service line ?
The Doctor’s Lounge Podcast@DRsLoungePod
Medicare created the heart team requirement for TAVR for a reason. A surgical opinion was supposed to be a check on the system. It isn't working. "People let you know if they're happy or not happy that you did not sign off on someone to get a TAVR. Let me just leave it at that." And if you're a young surgeon without referrals? You need to be on that heart team. You need the aortic call. You need the cases. "If I were desperate, I probably would have done the same thing. You've got to put food on the table. You're not doing anything illegal." That's not corruption. That's a system that put a young surgeon in an impossible position — and called it a check and balance.
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@scuff7 @steelthepuck The biggest takeaway I get from the @ales_hockey podcast is the importance of playing where you can be happy after your career has peaked
If Slovakia suits him at this stage, for whatever reason, I am glad the opportunity presented itself & wish him well
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@cardiacpolymath @steelthepuck It looks like he's moving to Eastern Europe so maybe it's a less physical league.
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Just seen that Brett Ritchie has signed elsewhere.
Something behind the scenes gone off?
It was rumoured he was meant to come back. Anyway. We move on.
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@scuff7 @steelthepuck Who knows why, but for the size and the pedigree I was hoping for more tbh,
Age catches up with people in different ways I suppose
Wish him & his family well
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@steelthepuck Hands up, I expected him moving on. He's a bloody good player, and he's also a wee bit of a hopper, he played his part here well, so if he's gone elsewhere, the very best of luck to him in whatever his career and life brings to him.
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It’s been announced that Brett Ritchie has signed for Vlci Zilina. We thank you for your time in Sheffield and we wish the best in your future endeavours 🍊🏒
#SteelersHockey
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@CMichaelGibson Must be a hypertensive female river
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En route to speak about distinguishing epicardial coronary disease from microvascular disease and I looked down from 30,000 feet and saw the metaphor written across the landscape …
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@bealelab @yuanyi_z Hopeless with the NHS workforce issues & more of the same in terms of cluelessness Vs vision. A difficult one to support
To make a different kind of omelette, we're going to have to break some different kinds of eggs
I don't see that coming out of labour - or any of the others
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@yuanyi_z I'd be happy with Streeting. VG on assisted suicide for example.
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That is why neither man should win.
S. I. Rubinstein@si_rubinstein
Either Streeting or Burnham would be the first PM to have gone to Cambridge since Stanley Baldwin.
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Matt Daniels MD PhD retweetledi
My lab at @Stanford is looking to hire postdocs for multiple projects on cancer biology and therapeutics. Our recent work has uncovered some truly remarkable mechanisms for cytotoxic small molecules and we're looking to build on this research. If interested, see below:
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F.D.A. Commissioner Marty Makary Resigns After Weeks of Pressure nytimes.com/2026/05/12/us/… via @NYTimes
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@Tesslagra @MichaelMegalyMD @Hragy Cat like observations, that is all
Prognosis is probably defined more by the LV than the aneurysm
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@MichaelMegalyMD @Hragy Idk, get ready for the next case…not an IC but just monitor with CTA periodically to make sure it doesn’t dilate more
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#CardioX friends,
What would you do?
Isolated large true LM Aneurysm
70 F - EF 25-30%- no other clear symptoms.
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@wi_john Sorry to hear of your loss
May she rest in peace
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My mother died yesterday at the age of 93.Her life ended peacefully in the familiar surroundings of her care home thanks to the wonderful staff & district nurse team. An experienced GP familiar with my mother’s needs was a key factor in the decision making that facilitated this.
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@mukund @StellarInter9 Which credit card company adds 3.5% charge to the retailer?
Are they making a profit from the surcharge itself?
Is that legal?
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@StellarInter9 This place did not give any option to remove the 3.5% credit card fee.
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I rarely eat out.
Maybe once a month. Went yesterday to a restaurant (Italian, Mediterranean) in West Seattle for Mother’s Day last night.
Total for 5 of us ( we don’t drink alcohol) with one salad, humus and 3 vegetarian pastas was $97
The check said 3.5% surcharge for credit card. Then 17% service fee, mandatory.
Then tips were 20% 22% and 25% optional.
I asked if I could pay in cash.
No. They don’t take cash. Then how can I avoid the credit card fee I asked.
You can’t.
So I asked why the service charge.
It pays for the employees they said.
Then why the tip I asked.
It pays for front office staff
I don’t get it.
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HCMR nicely illustrates the role of NTproBNP, in addition to cardiac structure and function. You really gain a lot by incorporating NTproBNP into your practice, and this will allow us to put into context the results of various RCTs
#CardioTwitter
jamanetwork.com/journals/jama/…
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An example of photo bleaching and cell contraction during live cell imaging
A beautiful one
HHMI@hhmi_science
This mesmerizing timelapse captures the nonstop motion inside an animal cell. Moving red/orange streaks are the growing ends of microtubules, tiny “highways” that move proteins & other molecules within the cell. 📸: Andy Moore, HHMI’s Janelia Research Campus
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@AnthonyR945 @Bgreeny77 Let's just hope they grow organically as they bring in crowds and advertising and not bet the farm on the first season in a huge building that comes with its own fixed costs
I don't want to see an MCR presence evaporate again
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@Bgreeny77 New arena = should be able to attract a higher quality of player
Dow being a top 6 point producing defenceman, yes he produced less than Welsh but Dow’s been doing it in the league on a consistent basis
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Guys manchester are looking scary for next season….
Manchester Storm | #Homecoming@Mcr_Storm
✍️ 𝗪𝗘𝗟𝗖𝗢𝗠𝗘, 𝗧𝗛𝗥𝗘𝗘-𝗧𝗜𝗠𝗘 𝗔𝗟𝗟-𝗦𝗧𝗔𝗥 𝗗𝗥𝗬𝗗𝗡 𝗗𝗢𝗪 Manchester Storm are thrilled to announce the signing of veteran blueliner and three-time All-Star Drydn Dow, most recently with the Dundee Stars. The 33-year-old import defenceman has been a prominent figure for the Stars, spending all seven of his Elite Ice Hockey League seasons in Dundee. In 369 EIHL appearances, Dow recorded an impressive 261 points, tallying 67 goals and 194 assists. 🗞️ manchesterstorm.com/manchester-sto… #Homecoming
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@steelthepuck I think it is great that we can see players carve out a career between the teams in the EIHL (and NIHL?)
It might be a season long interview process, but some of the "smaller" clubs have often identified serious talent that the bigger clubs have missed
Besko
& Bakala
Stand out
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Moving from one of the big four to a rink team. Interesting.
Cardiff Devils@cardiffdevils
📣 𝗣𝗟𝗔𝗬𝗘𝗥 𝗦𝗜𝗚𝗡𝗜𝗡𝗚 𝗡𝗘𝗪𝗦 📣 ✍🏻 A new 😈 for the 2026/27 season - welcome Nicholas Welsh! 📰 bit.ly/4eWDaXp
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@Lab_Nagai Getting old may be difficult
But it beats the alternative
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