Christina Ennis

🎉 My manuscript is now available on bioRxiv! 📄 We found that #exosomes from diabetic patients drive more aggressive breast cancers by altering tumor behavior & immune evasion in #organoids. @GdenisBoston @BU_Tweets 🔗biorxiv.org/content/10.110… #CancerResearch #phdlife #womeninSTEM

Honored to have the opportunity to share my research @NCICancerBio !! #womeninSTEM

Excited to share our review that just came out in @FrontEndocrinol highlighting the perturbations to the #BreastCancer tumor microenvironment in #type2diabetes @RnDries @GdenisBoston frontiersin.org/articles/10.33…

.@tperrybrown really brought the session home with a moving presentation on her & her family's experience with cancer and what needs to be done to make sure Black patients aren't left behind. Thank you for reminding us of why we do what we do as cancer researchers. #NCIJI2022

Research highlight: Adipocyte-derived exosomes may promote breast cancer progression in type 2 #diabetes go.nature.com/3ExVIr7 @NaserJafari26 @kolla284 @ancasey8 @bellapompa @cs_ennis @CarlaMBoston @Nabil_Rabhi1 @StephenRFarmer1 @GdenisBoston

New research identifies exosome-mediated cross-talk between #BreastCancer cells and fat cells altered by insulin resistance – potentially explaining the link between breast cancer #metastasis and conditions like #type2diabetes. @GdenisBoston @The_BMC fcld.ly/246hx5c

Fat cells from patients with #Type2Diabetes can “communicate” with #BreastCancer cells and promote their growth—a finding that might explain the link between metabolic conditions and breast cancer metastasis. fcld.ly/kv3jkbl @scisignal

Racism affects all aspects of health. To solve disparities in healthcare we must solve the underlying discrimination that led us there.

1/ Our work on adipocyte exosomes and breast cancer in type 2 diabetes, in @scisignal. Full text at science.org/doi/10.1126/sc… Excited to share details from @naserjafari26 @kolla284 @ancasey8 @bellapompa @cs_ennis @CarlaMBoston @Nabil_Rabhi1 @StephenRFarmer1

Proud to be a part of this exciting study!

2/ #bmt (#alloSCT) can cure otherwise incurable blood malignancies, largely through destruction of leukemic cells by donor immune cells = graft-versus-leukemia (#GvL) effect.

1/ Can leukemic cell intrinsic features shape #bmt outcomes? Great team effort to address this in @ScienceTM! Thx to Wu lab, @KharchenkoLab, @getz_lab, @BeTheMatch, and #patients @DanaFarber for support! stm.sciencemag.org/content/12/561….

Our paper, led by @pbachi, looking at genomics of #CLL relapse post bone marrow transplant, out now in @ScienceTM. Thanks to all involved especially @KharchenkoLab . stm.sciencemag.org/content/12/561…

Excited to share our @biorxivpreprint on longitudinal #singlecell mapping of T cells with novel #machinelearning methods! We found exhausted T cells with divergent dynamics and distinct circuitry defining #immunotherapy response in human #leukemia tinyurl.com/ybj7amed