d1944
2.1K posts

d1944
@d1944d1944
Ducunt volentem fata nolentem trahunt
Germany Katılım Ocak 2014
99 Takip Edilen92 Takipçiler

@realrutie @_kittypunk Meine Erfahrung ist, dass niemand ein Auto haben möchte, womit man nicht in einem Rutsch 400-500 km fahren kann. Unabhängig davon, ob man das wirklich braucht.
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@d1944d1944 @_kittypunk Wenn man nur in der Stadt unterwegs ist, reicht das locker.
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@Twiterofilo1 I would give a high financial penalty for the club. The club is driving the culture.
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En el PSG está instalada la cultura marroquí. Sus recogepelotas actúan igual que lo hacían los de Marruecos en la Copa África. Qué asco de equipo y de afición.
Prime Video Sport UK@primevideosport
The PSG ballboy refused to give the ball back to Neuer last night 😳
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"The license for WEATHER has expired. Information about extension options are available at your Audi Partner or on the Audi Web Page"
Oh boy 🤣 You can't make that up!
sandro@sandroaufdie1
alter ist das respektlos
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@bryan_johnson I had a colonoscopy without anesthesia. It wasn't too bad, the prep was far worse.
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I got put under and had probes inspect my gastrointestinal tract. Down my throat and up the anus. It was my first bidirectional endoscopy.
Right before the anesthesiologist injected, I thought "This is the end. This is how I die. What could make the internet happier?" Then it was lights out.
This was important to do because colon cancer is now the #1 cancer killer under 50, and rising fast.
Early onset colorectal cancer incidence has more than doubled since 1994, climbing roughly by 3% per year in 20 to 49 year olds and 8% in 20 to 29 year olds.
Even though I routinely do all sorts of painful things to my body and mind for this project, this procedure had been weighing on me. I didn't want to go under and, you know, didn't love the idea of the probes being snaked through my body. Glad it's over and it honestly was not as bad as I had anticipated.
Here are my results:
+ doctor gave me a 10/10 score
+ no polyps
+ no inflammatory bowel disease
+ no diverticulosis, a common colon-aging marker
+ we are awaiting biopsy results
Colonoscopy screening can save your life. A meta-analysis of over 4.7 million people found colonoscopy was associated with 52% and 62% reduction in colorectal cancer incidence and mortality.
A regular full body MRI (I get one every 6 months) can't reliably detect early colon lesions or polyps. A colonoscopy remains the gold standard for both detection and removal.
The recommended screening age has been lowered from 50 to 45 in 2021.
Half of early colorectal cancer cases now fall in 45 to 49 year olds.
Obesity is a genuine colorectal cancer risk factor. A meta-analysis involving over 66,000 participants found obesity raises early colorectal cancer odds by roughly 50%. Yet it is unlikely to fully explain the under 50 surge.
A new study surfaced an unexpected culprit. Across 10 cohorts and 29 lifestyle and environmental signatures, comparing tumor DNA methylation in early-onset (<50) vs late-onset (≥70) colorectal cancer, one signal stood out: the herbicide picloram.
Early onset tumors showed ~3 fold higher odds of carrying the picloram methylation signature in the discovery cohort, and 1.77-fold across all 10 pooled cohorts (114 early onset vs 372 late onset).
Across 94 US counties over 21 years (1992 to 2012), picloram-use intensity correlated with increase in EOCRC incidence, the most robust signal among 62 pesticides tested.
Early onset tumors carried a lower obesity methylation signature than late onset, suggesting that environmental toxins, more than metabolic dysfunction, are the dominant epigenetic driver in young patients.
Epigenetic drift drives biological aging and most age-related disease: chemicals assumed safe because they aren't directly genotoxic may still predispose us to cancer and chronic disease over decades through methylation and gene-expression disruption
It's time to ring the alarm: every additive chemical in our food, water, and environment needs re-evaluation through a long term, population-based epigenetic and gene expression lens, not just acute genotoxicity assays
Epigenetic disruption by environmental toxins is likely a key driver.

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@vitz_maximilian Die realistische Reichweite vom 25000€ VW ID Polo ist unter 200km??? Bitte sagt mir, dass ich mich irre....
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Immerhin fängt er bei knapp 25.000€ an. Das ist noch ein angemessener Preis für die Fahrzeugklasse.
Zum Vergleich: Für 37.000€ bekommt man ein Model 3 Standard mit 534 km Reichweite. Für 45.000€ ein Model 3 Premium (RWD) mit 750 km Reichweite und 320 PS!
Maximilian Vitz🗽⚡️@vitz_maximilian
42.000€ für den neuen VW ID.Polo? Das muss doch ein Fehler sein.
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@markusdd5 @atheistsplained Ich wurde belächelt, als ich behauptet habe, dass Christian Lindner der deutschen Politik enorm fehlen wird. Here we are.
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@atheistsplained war sehr unpopulär zu der Zeit aber man muss Christian Linder einfach bescheinigen, dass er vollumfänglich mit allem Recht hatte.
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@Electric_Maik Der neue ID Polo untermauert nur, dass das Tesla Modell 3 und das Modell Y unschlagbar sind, wenn man das Preis-Leistungs-Verhältnis betrachtet.
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@markusdd5 Sabine is awesome… I wish the German mainstream media would work with people like her… she is the right influencer we all need
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She's not getting nearly enough credit for the grunt-work she is doing and the hate she's enduring for uncovering the insanity that is modern academia funding structures.
I was very much lucky to have a studied at a university where research was largely funded by 3rd parties and industry that closely partnered with academia and hence had and has a real interest to pursue things that lead to practically testable and verifiable outcomes.
But that is easier in fields closer to engineering.
In foundational physics, that is much harder to do because just understanding what makes sense to fund is already more difficult and then people with the most intimidating paper or prettiest Powerpoint win. Not the ones doing the actual useful work.
Sabine Hossenfelder@skdh
String theory didn't just fail, it's far worse.
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@UlfKollwitz Am Ende verstehen die meisten, das Preis-Leitung bei Tesla zurzeit unschlagbar ist.
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Nur Info:
Tesla : Ende einer Ära (30.11.25)
16.04.26 auto motor und sport:
Mit knapp 9.200 Neuzulassungen insgesamt rasiert der E-Auto-Pionier wie zu besten Zeiten die versammelte Konkurrenz. 6.841 neu zugelassene Model Y bedeuten einen spektakulären ersten Platz in der Neuzulassungsstatistik, mehr als VW ID.3 und ID.4 zusammen.
Wer jetzt glaubt, dass Elon gemauschelt und mit Eigenzulassungen oder Gewerbeverkäufen die Statistik geschönt hat, irrt sich. Denn ein weiterer Wert ist spektakulär: 86 Prozent der neu zugelassenen Tesla Model Y gingen an Privatkunden, beim VW ID.4 waren es im Vergleich gerade einmal 12 Prozent

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@eurofounder Only idiots think that this could solve problems in society.
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I wish Europe would do the same for ultra rich (net worth over €150K)
Mayor Zohran Kwame Mamdani@NYCMayor
Happy Tax Day, New York. We’re taxing the rich.
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@BrianRoemmele It`s an advantage to have the eyes on the highest possible position.
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@CWRoehl @c_lindner Es gibt anscheinend offensichtliche Absprachen zwischen den Anbietern hinter den Kulissen, um den Preis in einem bestimmten Range zu halten. Das ist extrem schädlich für den Wettbewerb.
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@c_lindner Bei allem Respekt, aber warum der Markt ausgerechnet hier nicht regeln soll, das konnten Sie schon 2022 nicht erklären und daran hat sich nichts geändert.
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Der #Tankrabatt ist zurück. Es ist eine späte, aber richtige Entscheidung. Autofahren darf nicht zum Luxus werden. CL
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