Dan

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Dan

Dan

@danj_h

Paramedic Practitioner • Digital Transformation • SI: Diabetes, CVD, Careplanning 🪴 🏳️‍🌈

Berkshire, UK Katılım Ocak 2018
2.2K Takip Edilen2.9K Takipçiler
Dan
Dan@danj_h·
@DrSteveTaylor But it’s ok because it was down to a ‘third party’…:
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Dr Steve Taylor
Dr Steve Taylor@DrSteveTaylor·
GP software EMIS down nationally for 45 mins Let’s do the maths! 58% of practices 3654 practices 52900 appointments potentially lost £1.2 million pounds lost Compensation to practices £0.00
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Michael Albert, MD
Michael Albert, MD@MichaelAlbertMD·
"Just stop taking it and keep the weight off." That's not how chronic disease works. I just published the most comprehensive breakdown of what actually happens — hormonally, metabolically, neurologically — when you stop GLP-1 therapy. 48 studies. 9,000+ patients. 3 meta-analyses. Here's what the data show: → 60% of lost weight returns within 1 year → Regain starts within weeks — not months → Your hormones fight you for YEARS after weight loss → But the regain curve decelerates. ~25% of the benefit may persist. → And reduced-dose maintenance strategies are showing real promise. This isn't a willpower problem. It's a biology problem. And the science is not ambiguous. Full article: substance-over-noise.beehiiv.com/p/why-weight-r… ↪️ michaelalbertmd.com #SubstanceOverNoise #GLP1 #ObesityMedicine
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Dr Paddy Barrett
Dr Paddy Barrett@Paddy_Barrett·
In your 40s, your statin number need to treat (NNT) might be 500. To prevent an event over 4-5 years. But your NNT after 40 years (at 80) drops to about 4. Some people spend their whole lives arguing about the 4-year number And never live to understand the 40-year one.
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Shivani Misra
Shivani Misra@ShivaniM_KC·
Yes. All these physicians are ‘sensible’ and ‘pragmatic’ and ‘evidence-based’ until it comes to weight loss and then something happens to them all….it’s actually a very simple and human thing… …they let their own biases and experiences override their limited understanding of metabolism Everyone has lost and gained weight. Or had someone close to them that has. It’s an almost universal experience. We all know what worked for us and what didn’t. Many HCPs believe in “pull your socks up, where’s your willpower and discipline” “when I was naughty I gained 5kg but then I was strict and lost it, you can do it too” Those lean also believe that they’re thin because they live their life in discipline. That maybe partly true but there are so many other factors. They believe patients who live with obesity and its consequences are weak-willed or feckless. And this underpins weight-related stigma which is perpetuated throughout the medical profession. Which is why you see ridiculous PowerPoints “GLP-1 undermines lifestyle efforts” Do some CME/ CPD and FFS learn about biology of weight and appetite and then talk to your patients. Things have moved on from “eat less and move more”
Michael Mindrum, MD@MichaelMindrum

Just wondering why otherwise scientific and evidence informed physicians that brand themselves as “sensible” can confidently hold ignorant and harmful attitudes about obesity? (Rhetorical question.) This bias irritates me to no end because during a consult, I often ask if they have ever experienced harm or judgement from a physician or health care provider about their weight. The stories they share are immediate, tangible, and relevant - they don’t have to think hard to come up with examples. Their impact can be devastating but talking about them, apologizing on behalf of medicine and our ignorance can be helpful. Medicine has done a lot of harm to patients - especially with obesity. I have brief conversations with specialists longitudinally over time to try to challenge and correct their bias because bias doesn’t tend to resolve in one meeting. I don’t think they are bad people - it is just a cognitive bias that causes harm and needs to be corrected. I will do my best though to protect patients from them and choose a different specialist for them if I can. There is irrefutable evidence now and deep understanding of obesity as a biologically driven complex disease that is not simply due to personal choices and behaviour This is why, when I hear ignorance from physicians on social media, it bothers me and think it needs proper push back.

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Abdelhamid Hamdy
Abdelhamid Hamdy@abdelhamed012·
We are "flying blind" on nearly 50% of our most vulnerable kidney patients. 🩺 I recently reviewed the data from the resident clinic; primary care screenings revealed a startling "Clinical Blind Spot." We are checking blood work (eGFR), but we are forgetting the urine (UACR).
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Prof Kamlesh Khunti
Prof Kamlesh Khunti@kamleshkhunti·
🧪 SGLT2 vs Insulin: What Happens to Beta Cells? In a cross-over study (n=17), empagliflozin was compared with NPH insulin at similar glycaemic control. 📉 Despite equal glucose levels: • 🔬 Beta cell glucose sensitivity ↑ • 💪 Insulin sensitivity ↑ • 💉 Insulin levels were lower vs insulin therapy 🧠 Suggests SGLT2 inhibitors may enhance β-cell function beyond glucose lowering #T2D #SGLT2 #Empagliflozin #BetaCells #MetabolicScience link.springer.com/article/10.100…
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Abdelhamid Hamdy
Abdelhamid Hamdy@abdelhamed012·
Type 2 Diabetes in Adults: Management – NICE Guideline NG28 (Updated February 2026)
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NICE
NICE@NICEComms·
📢Big shift in type 2 diabetes care NICE now recommends SGLT2 inhibitors first-line for cardio-renal protection from day one. Evidence suggests 17,000 deaths could be prevented over 3 years, along with £560m in cost savings for the NHS: nice.org.uk/news/articles/…
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Abdelhamid Hamdy
Abdelhamid Hamdy@abdelhamed012·
SGLT2i not for all
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Charlie Lees
Charlie Lees@charlie_lees·
How do you actually act on a faecal calprotectin result? We've been refining this in Edinburgh for 20 years. Here are the three tables from the new Atomic IBD post; starting with the one you can use in clinic tomorrow. "Monitor, monitor, monitor ... and act on the results of the monitoring." Different clinical situations need different responses. • First presentation isn't the same as routine monitoring. • "Grey zone" results need context. • And the 250 threshold is a decision point, not a diagnosis. We taught this to everyone: doctors, nurses, pharmacists, administrators even surgeons.
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Brandon Luu, MD
Brandon Luu, MD@BrandonLuuMD·
Most people aren’t ghosting you because they don’t like you. They’re overwhelmed. Information overload and task pressure drive anxiety and avoidance. But messages that feel useful cut through and get faster replies.
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AJPC
AJPC@AJPCardio·
New systematic review and meta-analysis shows that cardiovascular-kidney-metabolic syndrome staging is strongly associated with risks of all-cause and cardiovascular mortality, highlighting the importance of integrated risk assessment in practice. ow.ly/IVXQ50Y0RzI
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Dr Alo, DO, FACC
Dr Alo, DO, FACC@MohammedAlo·
🫀 Ozempic isn’t just about weight loss — and the data may surprise you. A landmark clinical trial just showed that semaglutide reduced major heart attacks, strokes, and cardiovascular death by ~20% — even in patients WITHOUT diabetes. Here’s the twist 👇 🔹 The heart protection was NOT tied to how much weight patients lost 🔹 Benefits were seen regardless of starting weight or BMI 🔹 Only ~⅓ of the heart benefit came from waist reduction 🔹 The rest appears to come from direct cardiovascular effects So what’s really protecting the heart? And why does this change how we should think about GLP-1 medications like Ozempic? 👉 I break down the SELECT trial, the mechanisms behind the benefit, and what this means for patients with heart disease in my latest blog. 📖 Read the full analysis here: DrAlo.net/blog This may change how we define “success” in cardiology and weight-loss medicine. Please reshare! #HeartHealth #Ozempic #Semaglutide #SELECTtrial #Cardiology
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Greg Double
Greg Double@Dubstep1988·
We will need a government inquiry into every single conviction that Amanda was involved in. We could be looking at Post Office scale wrongful conviction scandal. #TheTraitors
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Abdelhamid Hamdy
Abdelhamid Hamdy@abdelhamed012·
🩺 CKD “remission” is now a realistic target, not a slogan ✅ New paradigm: shift from “slowing inevitable decline” to maintaining kidney health. 🎯 Proposed remission definition: •Chronic eGFR slope <1 mL/min/1.73 m²/year, or •Normal eGFR plus no albuminuria.
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Prof Kamlesh Khunti
Prof Kamlesh Khunti@kamleshkhunti·
🩸 SGLT2 inhibitors protect kidneys at all stages Meta-analysis of 70,000+ participants across 10 RCTs SGLT2 inhibitors ⬇️ CKD progression risk by 38% Effective regardless of eGFR or albuminuria, even in stage 4 CKD or minimal albuminuria. 💪 Consistent kidney protection across diabetes, CKD, and heart failure. #SGLT2i #Nephrology #CKD #CardioRenal #T2D #EvidenceBasedMedicine jamanetwork.com/journals/jama/… @brendonneuen @mvaduganathan @DLBHATTMD @JavedButler1 et al
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