Daniel Hussey
2.3K posts
Daniel Hussey
@danrhuss
Engineer, med student | Shipped satellite code to orbit (CUAVA-1)
Sydney, Australia Katılım Temmuz 2018
947 Takip Edilen258 Takipçiler
The full deck on Sid’s cancer approach is here:
sytse.com/cancer/
Worth a read. Raw data for download is also available and linked in the deck
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Evidence-based medicine is a blessing of the 20th century. Evidence-based medicine is also a curse of the 20th century.
Medical interventions are studied through randomized controlled trials and those interventions are assessed for efficacy and safety on a population level. But no individual quite matches some blended average of every trial participant. Rather, everyone's biology is unique.
Sid Sijbrandij just presented the story of his cancer journey at OpenAI forum. When Sid ran out of evidence-based treatment options, he didn’t accept the boundary but rather began treating his cancer like an engineer:
- multi-omic tumor profiling at extreme depth
- N=1 drug development (vaccines, TCR-T, radioligand therapy)
- parallel treatment strategies
- continuous measurement (ctDNA, single-cell, immune state) and refinement
Rather than protocol-based care, Sid built a learning loop. Maybe the future of medicine in a world where gathering and interpreting data gets cheaper and cheaper looks more like a loop.
Thanks for sharing @sytses and @jacobjstern !
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tide's going out - about to see how naked Australia's been swimming economically and politically
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@iamgingertrash i'd made a modest bet against 20% unemployment eoy 2027
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The wave of model capabilities
isn’t slowing down,
at all
There is a very good chance
of 20% unemployment eoy 2027
Stockpiling compute is a good idea
Another B200 will be purchased by us
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@BhagsNStonks @cmkusher i'd be willing to bet against significant ai job loss
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One thing I would say to first home buyers or any owner-occupier buyers from my own experience, is that what the bank is usually willing to lend you is way more debt than you should be prepared or comfortable taking on.
Cameron Kusher@cmkusher
Imagine being a first Home Buyer in Sydney you take advantage of the Home Guarantee Scheme and buy in October stretching yourself to spend $1.5 m on your home. With a 5% deposit no LMI and you expect interest rates to fall. The RBA was already beginning to think interest rates were too low (as stated today) and would have to rise. It’s now March interest rates have already risen 50 basis points and are expected to rise another 50 bp this year and potentially as much as 75 bp. You were assessed on a 3% serviceability buffer but you have a baby on the way and you are facing reduced incomes and then childcare for the next five years. The cost of everything is also going up because inflation is still too high. This is the type of situation some people that utilised the Home Guarantee Scheme may now be facing. It’s why the Scheme was so misguided and now these FHB may end up paying the price.
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@eigenrobot Things are fine atm. Public transport is a bit full, but I haven't noticed any other difference in inner Sydney.
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how boned is australia rn. heard theyre queuing up rationing, is that probably going through?
quite curious, seems like there are plenty of native resources and infrastructure?
did they shut stuff down bc climate or do they just have the wrong refinery configuration?
Aus Integrity@QBCCIntegrity
China has cut Australia off for Jet A1 fuel (kerosene), all of next months shipments cancelled. Normally 12/month. There’s one ship inbound. That’s it. China is Australia’s largest Jet Fuel supplier.
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I ask my son to ask his teachers what a large language model is, about once every six months (he knows, from me).
So far none have known.
Neither have they tried to find out to explain it.
NZ teachers are not preparing children for the world we have today, let alone tomorrow.
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Intergenerational equity = code for redistributing wealth from older people who earned it, to younger people who didn't.
Financial Review@FinancialReview
For the first time in 40 years, Baby Boomers are no longer the driving force in parliament as Jim Chalmers prepares a budget focused on intergenerational equity. ebx.sh/rkhFSJ
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@daviddorg Yeh, ground truths are hard all around in neuro. Are you getting DWI scans and mapping a connectome? Or just doing volumetric stuff?
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@danrhuss Question is more about how detectable it will be on a standard MRI or even a Neuroquant
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Today I am scanning my brain before I spend a year without screens
Doctors expect brain function to change, but whether the structure itself changes, nobody seems to know
All the data will be public: baseline, 6-month, and 12-month scans included
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If the central bank is serious about getting core inflation back to its 2.5 per cent target, it will need to abandon its dual goal of keeping the unemployment rate low, writes economist Paul Bloxham. ebx.sh/oY8zoc
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Young people actively sabotaging their chance at homeownership in Australia is something I struggle to understand.
AusPoll@AusPoll6
Federal voting intention (Gen Z) 🟩 GRN: 32% 🟥 ALP: 32% 🟧 ONP: 10% 🟦 L/NP: 10% ⬜️ IND: 6% ⬛️ OTH: 10% YouGov | 17-24 Mar | n=~400 [subsample of nationwide poll]
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@NatedawgO7 Always ask where the money is coming from and act accordingly
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Well this seems dodgy as fuck. Buyers agents being paid by the developers
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Solar panels ✅
“Didn’t get no handouts” ✅
Sunshine Coast ✅
Insufferable ✅
The Guardian have found the ultimate boomer.
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gm friends and friends of friends . how are yall today? what did u have for breakfast?
Nikita Bier@nikitabier
We're testing a new reply setting on posts: We're expanding the "Accounts you follow" option to include their followers too: your 2nd degree connections. This allows a wider audience to participate—but still keeps things intimate Early access available to Premium+ subscribers
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people love to mistake a framing for a reality, and then forget to ask if the framing is actually a useful one
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