Amit Das

In the spirit of being more organized and productive, and also set some goals, I have decided to run ongoing threads on the books, music, movies, analytics research etc.

@os7borne Stack used?

Vibecoded myself a board of advisors. A firehose of knowledge from the greatest investors! ingested writings, memos, podcast transcripts, interviews & more. I'm yet to upload every literature available but this is a good start. Warren, Howard & others are on speed dial now! :)

I got a newsletter from newsletter@narendramodi.in . When did I sign up though? #consent not required? Isn't my emailid also sensitive info? #dpdpa dear MEITY?

We’ve trained a multimodal AI model to turn routine pathology slides into spatial proteomics, with the potential to reduce time and cost while expanding access to cancer care.

25 years ago at Eden Gardens Rahul and I shared a partnership that will forever remain special. In a moment when the game looked beyond us we chose belief, patience and resilience. That stand was not just about runs but was about trust, teamwork and fighting for every session. Grateful to have shared that journey with Rahul and to be part of a Test that reminded us all that in cricket comebacks are always possible👍 @BCCI #PowerOfPartnership #Believe #Resilience

@maliksanchit Might? :)

In an era of flat pitches and aggressive batting, Jasprit Bumrah might just be the greatest bowler of the 21st century.

@mohanstatsman @cricket_badger Btw. India did not win everything in this wc either. :)

@cricket_badger When the Aussies won everything in the 1990s and 2000s, no one remotely suggested this.

International cricket is going to get very boring if India wins absolutely everything. It’s not good for the sport at all. #T20WorldCup

So many crucial little performances for India. Tilak Varma at the end, Hardik Pandya everywhere, Axar sensational in the field.... But the diamond that is forever is Jasprit Bumrah.

Brilliant. Brilliant. Brilliant.

There is a lot of hurt all round. The fans devastated , disappointed , angry. The players are hurting badly too. I have been in similar dressing rooms. It’s not easy. But this responsibility comes with the turf. It’s a burden and a great privilege to represent your country and

1. Works 24x7 2. Tweets in many different languages 3. Plans for a very long timeframe - till 2047 4. Hallucinates once in a while. I AM CONVINCED THAT PM MODI IS AN AI AGENT!!! Right person to inaugurate the AI Summit.

om.co/2026/01/16/our… lovely article by @om - DBA!

@Interiorarchdes @grok what are the likely dimensions of this room

Two daughters in one room, two beds side by side!

CRISPR deleted the extra chromosome behind Down syndrome. In a groundbreaking world-first, researchers have successfully used CRISPR gene-editing technology to remove the extra chromosome responsible for Down syndrome, opening a potential path toward treating genetic disorders previously considered incurable. Down syndrome, or trisomy 21, occurs when a person has three copies of chromosome 21 instead of the usual two. It is one of the most common genetic conditions, affecting about 1 in 700 babies worldwide, and leads to intellectual disability, developmental delays, and various health issues. Until now, no treatment has been able to correct the underlying cause. That may soon change. In a new proof-of-concept study, scientists applied CRISPR-Cas9 to cells taken from people with Down syndrome—including skin cells and pluripotent stem cells—and successfully eliminated the extra chromosome 21. The edited cells showed a striking return to normal gene expression patterns and cellular function. To improve precision, the team briefly disabled certain DNA-repair pathways during the process, making the chromosome removal cleaner and more effective. At this stage, the technique has only been demonstrated in laboratory cell cultures and is far from ready for human use. Removing an entire chromosome carries significant risks, including possible off-target effects, so extensive safety work lies ahead. If those challenges can be overcome, however, the approach could one day be applied to brain cells or even used during early fetal development. The implications extend beyond Down syndrome. The same strategy might eventually treat other life-limiting trisomies, such as trisomy 13 and trisomy 18, which are often fatal in infancy or cause severe disability. For the first time, a tool exists that could, in principle, correct the root chromosomal abnormality rather than merely managing symptoms. ["Trisomic rescue via allele-specific multiple chromosome cleavage using CRISPR-Cas9 in trisomy 21 cells." PNAS Nexus, 2025]

@umperukacyera0 @grok is this AI generated?

I can’t imagine what it feels like to fly this high with no safety line

Cricket, Soccer, Polo, Billiards, Snooker, waterpolo, ...

I run every day for 20 minutes & if I miss a day, I add 20 minutes to the next day. This has truly been a game changer. Tomorrow, I'm supposed to run for 4 months.

@rameshsrivats I wonder what would happen if Group B1 was possible...

This is not Group B. It's group H1B.

@CricketopiaCom @sachin_rt @bhogleharsha @ashwinravi99 @RaviShastriOfc @azharflicks @cricketwallah @anilkumble1074 @gauravkapur @therealkapildev @Imangadbedi who is the bottom right person? next to Kapil? and the chashmish left of Kapil?

Remembering Bishan Singh Bedi. A photograph from India’s tour of England, 1990 when Bedi was the Team Manager. How many players can you recognise in this pic?