David Chalmers

Vale, Jon Kudelka. Deeply saddened that one of Australia’s finest cartoonists has left us. His work was a joy to behold. Miss you, Jon.

@larissawaters Very sad news. He was a talented cartoonist and a good bloke.

Vale Jon Kudelka - a brilliant artist who knew the power of comedy in holding truth to power, and effecting change. His work showed a genuine and profound love for people and nature - often funny, often heartbreaking, but always incisive. Australia has lost a great today.

Contact Parallel Cascade Selection Molecular Dynamics (cPaCS-MD) for Accurate In Silico Prediction of Peptide Binding Free Energy #MolecularDynamics pubs.acs.org/doi/10.1021/ac… @davidkchalmers #JCIM Vol66 Issue1 #compchem

Please to share @Sleebs_Lab @WEHI_research latest research led my @MadelineDans and @Wenyin_Su demonstrating the on-target activity of plasmepsin V peptidomimetics in Plasmodium falciparum parasites using genetic and proteomic approaches. pubs.acs.org/doi/10.1021/ac…

Pleased @Sleebs_Lab contributed a small role in remarkable team led by Paola Favuzza and Alan Cowman @WEHI_research and David Olsen and John McCauley at MSD that developed MK-7602 now in clinical development for the treatment of malaria. thelancet.com/journals/ebiom…

This work on the drain of scientific publishing (why the system is broken, basically) seems mostly spot-on: arxiv.org/abs/2511.04820

Looks like it's going to rain. I better bring in my Boc groups

Interesting observation here. Novel and risky work has lower ‘impact’.

What happens before and after tenure? Check out our latest paper in PNAS @PNASNews: Tenure and Research Trajectories Led by Giorgio Tripodi, postdoc in my lab. Fun collaboration with Xiangzheng, @qian_yifan, Dakota Murray, @bfjo & @ChaoqunNi 1/n

R.I.P. Tom Lehrer If no one is going to post the story of the 84-year-old Lehrer writing a letter to 2 Chainz, I guess I'll have to

We turned medicinal chemistry into a card game, which takes 3-10 years to play. PDF: jabde.com/wp-content/upl…

Pleased to see our research is published @Sleebs_Lab @WEHI_research led by William Nguyen on the optimization of an antimalarial class that targets ROM8 & CSC1 ...stay tuned for more research on the intriguing role of ROM8 & CSC1 in parasite survival... pubs.acs.org/doi/10.1021/ac…

Sad end of #compchem era… After 30+ years of service, CCL - computational chemistry list will be closing… 😢

@olexandr Before the internet was the internet!

My op-ed on the large shift of drug discovery moving to China and policy steps the U.S. can take to keep the innovation economy in America. "Five years ago, U.S. drug makers didn’t license any new drugs from China. By 2024, 1/3 came from Chinese biotech" statnews.com/2025/05/06/how…

My latest cartoon for @newscientist

Truly honoured to receive the #MCCB2025 Peter Andrews Award for Innovation in Medicinal Chemistry and Chemical Biology. Grateful for the recognition of our work at @NitscheLab and @ANUChemistry! Congratulations to @PScammells on the well-deserved Adrien Albert Award!

Researchers at the CSIRO have been sent a Trump administration survey demanding they answer questions on diversity, gender ideology and whether they are studying “climate justice” theage.com.au/national/sugar…

Volume 4 of J. Immat. Sci. is here! 88 pages of beer-reviewed bullshit, free to read and guaranteed to please. Massive thanks to the folks at @sciencebrush for preparing our cover art! PDF (180 MB): jabde.com/wp-content/upl…