Deep Piction
17 posts
@DeepPiction
Using whole-body cell-level imaging to improve disease understanding and therapy development.
We’re hiring at @DeepPiction 🧠🔬 We are looking for a Scientist – Tissue Clearing & Image Analysis (m/f/d) to join our team in Munich. You will help drive tissue-clearing, light-sheet microscopy, and quantitative 3D imaging projects across internal R&D programs and collaborations with biotechnology and pharmaceutical partners. The role combines hands-on experimental work, project ownership, workflow development, and close collaboration with our AI and image-analysis teams. We’re looking for someone with strong experience in tissue clearing, fluorescence microscopy, light-sheet imaging, and large-scale 3D image analysis. Please apply with one single PDF containing your CV and cover letter to: hr@deeppiction.com Subject: Scientist – Tissue Clearing & Image Analysis (DP-TC-2026-01) Applications will be reviewed on a rolling basis until the position is filled. linkedin.com/jobs/view/4436…
Proud to be part of this team! 💪🧠🔬
How do you map every cell in an entire mouse without slicing it into thousands of sections? Our recently published paper in @NatureProtocols describes wildDISCO: a whole-body immunolabeling approach that makes the mouse transparent and labels cells throughout the body using standard antibodies. The result? Cellular-resolution 3D atlases of entire organisms, preserving the anatomical context that is often lost in traditional histology. Check more at: nature.com/articles/s4159… #SpatialBiology #Imaging #TissueClearing
How do you map every cell in an entire mouse without slicing it into thousands of sections? Our recently published paper in @NatureProtocols describes wildDISCO: a whole-body immunolabeling approach that makes the mouse transparent and labels cells throughout the body using standard antibodies. The result? Cellular-resolution 3D atlases of entire organisms, preserving the anatomical context that is often lost in traditional histology. Check more at: nature.com/articles/s4159… #SpatialBiology #Imaging #TissueClearing
Single-cell RNA-seq transformed biology, but we still sample <0.001% of an organism. 2D sections lose 3D context. What if we image the whole body first? We Introduce DISCO-seq🤩: full 3D imaging then scRNAseq👇🏻biorxiv.org/content/10.648… by @HarsharanBhatia, Laurent Simons et al.
Nature research paper: A deep-learning framework reveals whole-body perturbations at cell level go.nature.com/4dD02sq
Today in @Nature, we report MouseMapper: foundation-model AI to map disease perturbations across the entire mouse body cell-by-cell. In obesity, it revealed body-wide inflammation & unexpected facial nerve damage. 🧵👇🔉 nature.com/articles/s4158… led by @Dorie00 & @yingchen733
