Dearbhla Murphy dervmurphy.bsky

I am absolutely delighted to share our paper showing the induction of trained immunity by an adenoviral COVID-19 vaccine published in @jclinicalinvest this evening! A truly massive thank you to @ShareeBasdeo and the whole team for all their help 🥳🥳 jci.org/articles/view/…

@MartinBarr10 @JCI_insight Thanks Martin!

@derv_murphy @JCI_insight Congratulations @derv_murphy Great work! 👏

I am so excited to share this work from my PhD which has now been published in @JCI_insight ✨ In this study, we used IFN-γ to induce trained immunity in human macrophages and enhanced their ability to kill M. tuberculosis and MRSA. Read more here: insight.jci.org/articles/view/…

@BrenM2012 @JCI_insight Thanks Brenda!! And you ✨

@derv_murphy @JCI_insight Congratulations Dearbhla🎉🎉

We're celebrating the International Day of Women and Girls in Science! Let's look back on the life of Marie Skłodowska Curie: a Nobel Prize laureate who dedicated her life to science and became one of the world's greatest scientists. #WomenInScience #NobelPrize

ICYMI: For decades, memory-like responses in immune cells have remained unexplained. Katherine Y. King & team @BCMFromtheLabs now identify epigenetic changes in hematopoietic stem and progenitor cells in a mycobacterial infection model that are retained in downstream macrophages, providing mechanistic mediators of innate immune memory and explaining persistence of central trained immunity: doi.org/10.1172/jci.in… #Immunology

Delighted to have the opportunity to present at the TSJCI CaRes Seminar Series yesterday and share some of our recent and ongoing lung cancer organoid work @kathygately1 @CancerInstIRE

Fantastic session at the TSJCI CaRes Seminar Series with insightful presentations from Prof. Patrick Forde and Dr Christina Cahill, joined by Prof Gerry Hanna and Mary-Louise Neligan @CancerInstIRE @stjamesdublin @tcddublin @HSEDubMidlands

Our new paper is out in Scientific Reports! 🎉We show how dexamethasone can both calm inflammation and help macrophages fight #tuberculosis. So proud of our team especially @lorrainethong @stjamesdublin @TCDTMI @TBImmunologyTCD @BasdeoLab @TrinityMed1 nature.com/articles/s4159…

Online now: Electromodulation of human monocyte-derived macrophages drives a regenerative phenotype and impedes inflammation dlvr.it/TMqx66

✨New issue!✨ Check out the latest in #metabolism research from across all disciplines. Read about #TumourMetabolism, #Lactate signalling, #WeighLoss, #Thermogenesis, #DietaryInterventions and many more topics! nature.com/natmetab/volum…

@dublinbusnews hello I was wondering if a purse was found on a 37 bus?

Excited to share our latest publication demonstrating how BNT162b2 vaccination can reprogramme innate immunity to reduce and control inflammation against both targeted and non-targeted pathogens—suggestive of trained immunity!

So proud of this work from the amazing @SarahA_Connolly and @aaronbreathnach 🥳

New paper alert! 🥳We are so proud to share this amazing work from the lab led by @SarahA_Connolly and @aaronbreathnach. In this study, we show that the BTN162b2 mRNA vaccine induces anti-inflammatory trained immunity in humans 💉💉Read more here: sciencedirect.com/science/articl…

I'm delighted to share that I successfully defended my thesis yesterday! Thank you so much to my wonderful supervisors @DrMelissaConroy and @JoanneLysaght for all their support and to @BreakthroCancer for funding this PhD!

Scientists have uncovered how abdominal fluid called ascites in patients with high-grade serous #OvarianCancer suppresses antitumor cytotoxicity in #NaturalKiller cells. @lynchielydia @_Karen__S @donalb5 Learn more in Science #Immunology: scim.ag/43uqCz9

@maitiuomurchu @BreakthroCancer @JacinthaOS Aw this amazing Maithiú!! Huge congratulations🥳!!

Thrilled to have won the EACR Young Investigator Award at #IACR2025 in Belfast where I shared my work funded by @BreakthroCancer on developing a novel hypoxia-modifying agent to improve radiation resistance in oesophageal adenocarcinoma🧪

@LauraKanePhD Huge congrats Laura! 🥳

Honoured to receive a TCD School of Medicine Seed Funding Award yesterday! 🌟 This funding will be instrumental in enabling me to generate preliminary data for upcoming large grant applications to continue my #PancreaticCancer research!

We are so incredibly proud of Dr @grainnejameson for securing this wonderful funding! Dr Jameson is an incredible scientist and we are so excited to see where this research will take her!