DKFZ Epigenetics

@mrodpar When the cat‘s away, the mice will play 😉

Numerous studies connect healthy epigenomes with massive flammkuchen ingestion🧐. Our division was clearly compelled yesterday to further investigate these observations...

@SciWithRhi The CNS journals can accept and reject whatever they consider right for their profile. The problem is with the boards and panels that pay an inordinate amount of attention to these journals.

Game changing: @EMBOPress @Co_Biologists @eLife @PLOS @biorxivpreprint and others offer Review Commons: post preprint, preprints get peer-reviewed, then journal reach decision. This pooled submission accelerates publishing and reduces re-review. reviewcommons.org

@NatRevMCB proudly presents Focus on #Methylation in biology with 5 cutting-edge Reviews + commentary showcasing the latest understanding of the mechanisms and roles of methylation in animals and of its clinical relevance go.nature.com/2mmfHq1 ALL Reviews are FREE for 1 month!

#Methylation Focus issue @NatRevMCB: Comment by Frank Lyko @dkfzEpigenetics on the importance of non-histone protein methylation in cancer therapy go.nature.com/2NviZ7H

Please RT: come join our group and learn wet and dry bench techniques, equip yourself for an independent research career, collaborative project with @tuuliel #epigenetics nature.com/naturecareers/…

The programme is now online at nacht-der-forschung-heidelberg.de ! From 3pm till midnight, you can take part in a number of exciting events offering insights into the range of international research taking place in and around HD and Mannheim.

We are recruiting through the @dkfz postdoc program (dkfz.de/en/postdoc-pro…). If you are interested in a translational project on #skincancer and #SingleCell analysis, please contact us. Also see here for a more detailed project description: tinyurl.com/y37eyf89

Challenging dogma, metastasis of #cancer occurs early: lineage of driver mutations via exome sequencing shows early seeding in > 80% of colon cancer patients nature.com/articles/s4158… by @cncurtis @huzheng1 @StanfordMed and collaborators @NatureGenet

Excellent #postdoc opportunities in basic and translational #CancerResearch. Apply now for a Postdoctoral #Fellowship @DKFZ in #Heidelberg! Find out more at dkfz.de/postdoc. Application deadline: 15 September 2019. Please RT!

How a Chinese Scientist Broke the Rules to Create the First Gene-Edited Babies via @WSJ #CRISPR buff.ly/2VtOeDQ

Our first single-cell paper is posted! Loss of fibroblast priming in aging human skin.

The @NEBiolabs APOBEC-based enzymatic methylation protocol (EM-seq) is out! We see more even coverage across CpG islands & greater detection of CpG sites vs. WGBS; data coming soon from the @US_FDA @nygenome #SEQC2 #EpiQC study w/ @GenomeInABottle samples #Product%20Information" target="_blank" rel="nofollow noopener">neb.com/products/e7120…

A Secreted RNA Binding Protein Forms RNA-Stabilizing Granules in the Honeybee Royal Jelly cell.com/molecular-cell…

Epiproteomics, anyone? 😜

DNA (de)methylation in embryonic stem cells controls CTCF-dependent chromatin boundaries [Laura Wiehle @geejaytee Güenter Raddatz @chrsclrksn @dkfzEpigenetics @KarstenRippe Achim Breiling @TeifLab] genome.cshlp.org/content/early/… 5hmC loss > nuc gain > CTCF loss > 5mC spreading > gene↓

“Nongenetic inheritance could, in fact, be genetic in origin.” bit.ly/2EXtPvO

Diversity of cytosine methylation across the fungal tree of life nature.com/articles/s4155…

Scary article for those working with cell lines.

Ecological plasticity facilitates farming of marbled crayfish in Madagascar. Check out our new paper: rdcu.be/blB9M