Dom Sharlette

725 posts

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Dom Sharlette

Dom Sharlette

@domsharlette

Building product companies, not just products. 4 startups · 3 exits · 5 legacy companies transformed Digital Health & Connected Consumer Technology

NYC Katılım Aralık 2017
62 Takip Edilen372 Takipçiler
Dom Sharlette
Dom Sharlette@domsharlette·
A great late-night read.
Kirsten Green@kirstenagreen

There's a new playbook in vertical AI: building one compounding engine with two interfaces. In prior cycles, B2C and B2B evolved in distinct waves. Google and Amazon first built massive consumer audiences. Then, over years (decades), they exposed capabilities as infrastructure to the market. AWS didn't follow S3...it took time. The cycles were long and sequential. What we're seeing now is a compression of that happening in real time. Consumer and infrastructure aren't sequential anymore. They're simultaneous. The arc looks something like: • Launch as a consumer-facing assistant or tool • Build differentiated intelligence or interaction layer • Realize the leverage in embedding that layer elsewhere • Expose APIs / SDKs / agent capabilities as a natural extension of what the consumer surface already built • Evolve into both product and infrastructure My working hypothesis: Consumer builds... • Data • UX iteration • Brand • Real-world feedback loops Infrastructure builds.... • Revenue durability • Distribution hedge • Strategic leverage • Added valuation multiple In other words, consumer AI may increasingly function as the front-end acquisition, while infrastructure becomes an economic moat. They're not two separate businesses — they're one compounding engine. We’re seeing early versions of this pattern: @mindtripai — an AI travel planner now building an agent-first layer that can be embedded via API or integrated agent-to-agent. The consumer product builds the travel identity graph; the infrastructure ambition is to own the decision layer. @shopondaydream — a consumer visual shopping experience now powering visual search and recommendations directly on brand websites, decoupling the intelligence layer from the consumer UI. @duckbillai — a human concierge now introducing MCP to bring human-in-the-oop trust into broader agent ecosystems. @tryheroapp — a proactive daily assistant now extending AI Autocomplete as enterprise infrastructure embedded in third-party text boxes. The same predictive intelligence powers both surfaces. These companies aren’t just adding enterprise as a monetization path, but aiming to become vertical control planes — the intelligence layer others depend on — especially in a world where distribution may concentrate around a few dominant AI interfaces. If OpenAI wins distribution, you want to be the vertical brain it calls. If distribution fragments, you want to own the daily habit directly. Not all vertical AI → infra expansions are equal. The real question: is there a single intelligence core compounding across surfaces — or simply two adjacent products under one roof? The latter is just operational complexity, but the former is a control plane.

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Dom Sharlette
Dom Sharlette@domsharlette·
Replacing manual intake and fragmented record exchange is the real opportunity here. What’s notable is the move toward patient-directed digital tools that reduce repeated forms and missing records at the point of care. That’s the kind of infrastructure shift healthcare actually needs. bit.ly/3MCU953
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Dom Sharlette
Dom Sharlette@domsharlette·
Most wearables collect data well—and explain it poorly. What’s notable about Oura’s update isn’t AI. It’s the lab-style summary showing patterns, not points. That saves clinicians time and helps consumers act—without chasing streaks. bit.ly/3ZVBtR4
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Dom Sharlette
Dom Sharlette@domsharlette·
Most wearables already collect more data than we can use. The problem isn’t volume—it’s quality. If wrist-worn signals aren’t reliable, repeatable, and interpretable over time, they won’t survive clinical workflows. Better outcomes come from better data. bit.ly/4agJMgx
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Dom Sharlette
Dom Sharlette@domsharlette·
Fall risk is shifting from subjective screening to neurological signal. This app measures reaction time and multisensory lag as risk proxies. NIH backing here signals measurement infrastructure, not a solved prevention product. bit.ly/4qrb20A
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Dom Sharlette
Dom Sharlette@domsharlette·
Digital health is moving from engagement to infrastructure. Maven launching a research institute isn’t news—it’s an admission. Adoption doesn’t scale in healthcare. Evidence does. Engagement opens the door. Clinically legible outcomes keep you there. bit.ly/4tmOZed
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Dom Sharlette
Dom Sharlette@domsharlette·
AI isn’t the threat. It’s a mirror.
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Dom Sharlette
Dom Sharlette@domsharlette·
AI chatbots are driving health conversations—not clinical signal. They organize info but don’t produce validated, repeatable, accountable data. Until insight survives clinical workflows, conversational AI is an interface—not healthcare infrastructure. npr.org/2026/01/30/nx-…
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Dom Sharlette
Dom Sharlette@domsharlette·
Forerunner’s Top 50 list isn’t about AI for AI’s sake — it’s a snapshot of where consumer AI is being applied to remove real-world friction. The 50 Consumer AI Startups to join now, according to Forerunner open.substack.com/pub/nextplayso…
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Dom Sharlette
Dom Sharlette@domsharlette·
@kirstenagreen @ForerunnerVC Completely agree. Cost-cutting automation is an efficiency play — valuable, but finite. Empowering humans is where durable businesses and real upside get built.
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Kirsten Green
Kirsten Green@kirstenagreen·
humans& captures so much about what we @ForerunnerVC care about most in 2026. In the past 3 yrs, the technology shift has had a major narrative problem. Cost-cutting, job automation, efficiency – that is a massive market, but it has a ceiling, and it's not vision. There is a real future where AI helps us be more human, not less, and it’s a lot more interesting than where much of the market is spending time today. It was a clear yes to invest at the seed: nytimes.com/2026/01/20/tec…
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Dom Sharlette
Dom Sharlette@domsharlette·
FDA clarified the playing field: non-invasive wearables and AI can deliver health insights without being treated like full medical devices — as long as they don’t diagnose or treat. That’s a meaningful shift for consumer health builders and investors. More signal. Same responsibility. Execution matters now. bit.ly/4aYeXxO
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Dom Sharlette
Dom Sharlette@domsharlette·
Coming off CES, one thing was clear: health and data tech is shifting — quietly, but meaningfully. Non-invasive monitoring is moving beyond steps and sleep toward continuous health signal — scales, rings, wearables, and software ecosystems designed to support daily understanding, not just activity tracking. The shift isn’t the hardware. It’s the focus on insight, context, and everyday use. The data exists. How responsibly — and usefully — it’s applied matters now.
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Dom Sharlette
Dom Sharlette@domsharlette·
Because great outcomes aren’t born from dominance—they’re born from dialogue. Read the full article → bit.ly/480OPAc
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Dom Sharlette
Dom Sharlette@domsharlette·
When design and sales speak the same language, good ideas become market leaders. We explore why creative and commercial teams drift apart, how to bring them back together, and what happens when alignment becomes culture.
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Dom Sharlette
Dom Sharlette@domsharlette·
Our conversation is now live. @JanStillerman and I dive into how breaking silos between design and sales turns creativity into momentum.
Dom Sharlette tweet media
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