Frank Dondelinger

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Frank Dondelinger

Frank Dondelinger

@don_frank

Practicing machine learning by day, perfecting my baking skills by night. Everything else fits in between.

Basel, Switzerland Katılım Ağustos 2009
391 Takip Edilen329 Takipçiler
algobaker
algobaker@algobaker·
I feel like "trick to get to the top of the leaderboard" could be rephrased to "do what everyone should always do in a data science competition and consider the scoring function" even if this is a particularly extreme case Was always a bit unclear from the start whether the metrics they chose were going to hold-up well. Feels like something they could have pushed more on stress-testing before starting the challenge
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Frank Dondelinger
Frank Dondelinger@don_frank·
No value judgment in that by the way, there is a lot of value in thinking deeply and for a long time to understand e.g. sociological phenomena. It just won't lead to high publication output without an external incentive.
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Frank Dondelinger
Frank Dondelinger@don_frank·
CS is hardly lab based, unless you're building robots... My theory about this is that this is a difference between fields where the emphasis is on theories (which you can refine indefinitely) vs experiments (which have to finish at some point).
Florian Ederer@florianederer

Research output after tenure drops off a cliff for business, economics, sociology, and other non-lab fields. But it remains high post-tenure in lab-based fields such as chemistry, physics, computer science, and engineering.

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Frank Dondelinger
Frank Dondelinger@don_frank·
@JKSteinberger TIL there were two Austrians whose names start with H who tried to conquer the world -- and one may have succeeded.
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Prof Julia Steinberger
Prof Julia Steinberger@JKSteinberger·
You, it's been a shitty year and silver linings are effing rare, but I am still super proud I wrote this thing, which is not even original. I still need to incorporate some comments, but by golly I think I basically got it right. jksteinberger.medium.com/what-we-are-up…
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Daniel Paleka
Daniel Paleka@dpaleka·
It has not been reported much, but I believe ETH Zurich has, as of last week, banned new Master and PhD students who attended a long list of universities in China, Russia, and Iran. 🧵
Daniel Paleka tweet media
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Frank Dondelinger
Frank Dondelinger@don_frank·
In fact one of the main achievements of LLMs should be too teach us that much of what we admire in successful people (being articulate, formulating convincing arguments, accessing knowledge in their head quickly) is pattern matching rather than reasoning.
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Frank Dondelinger
Frank Dondelinger@don_frank·
I won't do as good a job as @NandoDF, but thanks to the @NobelPrize for giving me a decent chance at explaining both the Chemistry and Physics Prize. Computational biologist or polymath, you decide...
Nando de Freitas@NandoDF

For the first time in my life I can explain what the physics @NobelPrize is about! In fact, if you’d like to learn what is a Hopfield net and how it relates to NP hard satisfiability, Boltzmann machines, autoencoders, score matching, Maxwell demons, maximum likelihood, generative AI, quantum computing, unsupervised learning and neural networks, see these slides and video lectures from a course I taught at @ipam_ucla 2012 helper.ipam.ucla.edu/publications/g… m.youtube.com/watch?v=XYEs7k… youtube.com/watch?v=JlONAa… m.youtube.com/watch?v=t9sXdA…

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Nando de Freitas
Nando de Freitas@NandoDF·
For the first time in my life I can explain what the physics @NobelPrize is about! In fact, if you’d like to learn what is a Hopfield net and how it relates to NP hard satisfiability, Boltzmann machines, autoencoders, score matching, Maxwell demons, maximum likelihood, generative AI, quantum computing, unsupervised learning and neural networks, see these slides and video lectures from a course I taught at @ipam_ucla 2012 helper.ipam.ucla.edu/publications/g… m.youtube.com/watch?v=XYEs7k… youtube.com/watch?v=JlONAa… m.youtube.com/watch?v=t9sXdA…
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Richard McElreath 🐈‍⬛
Richard McElreath 🐈‍⬛@rlmcelreath·
I told a colleague that logistic regression is AI and they got mad at me, so I made a chart. Find yourself. I am "Tinder is AI".
Richard McElreath 🐈‍⬛ tweet media
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Frank Dondelinger
Frank Dondelinger@don_frank·
@anshulkundaje Agreed - - this is part of my long-running argument that what is holding back deep learning in biology is at least in part the lack of custom architectures that address biological processes.
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Anshul Kundaje
Anshul Kundaje@anshulkundaje·
The way forward is to focus entirely on clever ways to solve the E2G problem and the best ways to learn these effectively with no explicit supervision for this task from commonly used assays including single cell measurements. 4/
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Anshul Kundaje
Anshul Kundaje@anshulkundaje·
Nice work. The issue with current seq-> expression models in terms of their very poor performance on variant effect prediction is not that they need to see more variation data. The problem is they don't learn long range effects of enhancers effectively. 1/
Ruchir Rastogi@rrastogi02

Happy to share new work with @anikethjreddy, where we aim to improve Enformer's gene expression predictions on personal genomes. biorxiv.org/content/10.110…

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Frank Dondelinger
Frank Dondelinger@don_frank·
We have an open position for a Data Science Innovation Fellow in my group at Novartis Biomedical Research in Oncology! If you are interested in doing AI research with direct impact on oncology drug discovery, please see below. Feel free to reply or DM me. linkedin.com/jobs/view/3963…
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Laura Luebbert, PhD
Laura Luebbert, PhD@NeuroLuebbert·
Lior and I wrote a blog post about what it was like for me to find occurrences of duplicated (and seemingly manipulated) data as a first-year graduate student at @Caltech. I am speaking openly because I believe that we, as the scientific community, can do better.
Lior Pachter@lpachter

In a blog post, she tells the story of the reaction she received when she pointed this out to her (tenured) professor at the time, and to others. She was basically told not to waste her time: "a lot of the scientific literature has problems". liorpachter.wordpress.com/2024/07/02/the… 7/

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