Douglas Cannie

Should we rethink genetic testing in older #DCM patients?🧬 In this cohort of 686 patients: 📍median age 50, 62.1% male 📍1 in 5 patients over 55 years of age were genotype-positive 📍30% of genotype-positive patients >55 years had high-risk genotypes 📍Similar risk of ventricular arrhythmias & end-stage HF vs younger patients 📚Read more in #EJHF @EJHFEiC :
doi.org/10.1093/ejhf/x… #HeartFailure #Cardiomyopathy #Genetics @escardio @MarcoMetra @dougcannie @ath_bakalakos @ESC_Journals

@CompleatQuiz we won last week but alas didn’t receive our voucher. Can you message me to resend please?

Front page of The Times this morning for our lab, describing our use of artificial intelligence & panels of biomarkers to create new predictive test for Parkinson's Disease. It is an absolute privilege to work with the superb clinicians and scientists at UCL. #ParkinsonsDisease

@soph_cash @nottmhospitals Yes! Great news! Congratulations, Sophia!

Absolutely delighted to be appointed @nottmhospitals today, such an amazing team to join. Also (controversial) I think the best effort with Christmas lights I’ve seen

A deep dive into cardiac complications in Emery Dreifuss muscular dystrophy! academic.oup.com/eurheartj/adva… #ventricular #arrhythmias #heart #failure #EHJ #cardiotwitter @ESC_Journals @escardio

Emery-Dreifuss Muscular Dystrophy 1 is associated with high risk of malignant #ventricular #arrhythmias and end-stage heart failure 👉 bit.ly/47WN3y3 #ESCCongress #EHJ @ehj_ed @rladeiraslopes

Emery-Dreifuss Muscular Dystrophy 1 is associated with high risk of malignant ventricular arrhythmias and end-stage heart failure. A simultaneous publication of ESC congress presentations. academic.oup.com/eurheartj/adva… @escardio @ESC_Journals #CardioTwitter #heartfailure #arrhythmias

@rbarvil Thank you, @rbarvil! Great to see you at the @ESCCongress2023.

Congratulations @dougcannie !!!! Great work!!!

With thanks to our amazing collaborators from across Europe and the USA. @ProtonotariosA @ath_bakalakos @xenux88 @vnparikh @euanashley @rbarvil @FranBermudz @dr_pavia @KSavvatis

Very pleased to share our work on carriers of pathogenic EMD variants courtesy of EHJ. Male carriers have a risk of malignant ventricular arrhythmia similar to that of male LMNA variant carriers. @ESC_Journals @UCL_ICS @TheBHF academic.oup.com/eurheartj/arti…

Not all Dilated Cardiomyopathy is the same. ⬇️Building on #genetics data of more malignant phenotypes with RBM20 variants, at times with EF > 35%. We need to move towards identifying and managing individuals by their true pathology, rather than generic NICMP/DCM labels

I am pleased to share our editorial and review on the utility of FDG-PET imaging in patients with #ARVC that I and @eleanorwicks have co-authored! Myocardial inflammation is an emerging phenotypic feature with much to teach us! authors.elsevier.com/a/1heUUc5r%7Eb…

@ProtonotariosA Thank you for all of your hard work, @ProtonotariosA!

Well done to @dougcannie for putting together this excellent piece of work advancing precision medicine in patients with #cardiomyopathy!

@ProtonotariosA @ath_bakalakos @AnneDybro @fdefrutossemi @Bjerregaard91 @xenux88 @dr_pavia @rbarvil @LorenzoMonserra @fatkinlab @UCL_ICS

Delighted to see our work on RBM20 variants now out @Circ_Gen. Both male & female RBM20 variant-carriers are at high-risk of malignant ventricular arrhythmia with male sex strongly associated with end-stage heart failure. With thanks to @TheBHF and our amazing collaborators.

Do not miss the next Heart Muscle Talks session! Drs @matteodalferro and Alessia Paldino will be presenting on "The importance of the genotype on top of phenotype in managing dilated cardiomyopathies". 🗓Friday, 28/10/2022 🕟15:00 (BST) Register👉 ucl.zoom.us/webinar/regist…

@ProtonotariosA I’m not ready to talk about it

That brings up so many emotions @dougcannie

Very excited to see our paper on "Importance of genotype for risk stratification in #ARVC cardiomyopathy using the 2019 ARVC risk calculator" published at EHJ! @ESC_Journals @ehj_ed academic.oup.com/eurheartj/adva…

@UCL_IHI @alvinaglai @UCL_Wellbeing @PhDVoice @TheUnionUCL @ucl @Nanaki_M22 Cross?

✨Final Round✨ Looking at this sunset over Farringdon station, I spy with my little eye something that begins with the letter C 👀🔎 First correct guess wins a £10 Amazon voucher! @alvinaglai @UCL_Wellbeing @PhDVoice #PhD #postgrad #mentalhealth @TheUnionUCL @ucl @Nanaki_M22

@UCL_IHI @alvinaglai @UCL_Wellbeing @PhDVoice @ucl Begonias?

🎉 Round 2 🎉 Ahoy! Along the Regent's canal, you can spot 'Word on the Water'! At this quirky destination, I spy with my little eye something that begins with the letter B 👀 The first correct guess wins a £10 Amazon voucher! @alvinaglai @UCL_Wellbeing @PhDVoice #PhDlife @ucl