Egbert Castro

We're open sourcing the core agentic loop of Faraday! The exciting pace of building agentic science has led to the emergence of many AI scientist efforts, ranging in scale and complexity. It's great to see the design space of agentic scientists so rapidly explored and key points of leverage emerge in this space. We’ve been fortunate to be a part of this shared effort introduce a new paradigm of research to scientists across academia and industry. With this open AI scientist framework, we hope that scientists will be able to launch their own Faraday agents for their research tasks and explore ways agentic science can move forward. Today, you can use open-source Faraday to do many everyday research tasks with optional extensions like integrating custom tools or scalable hypothesis testing.

really nice to see test-time scaling via latent search. Huge congrats to the team!

labs will publish details on arch, optim, objectives, scaling, kernels, literally everything except data and academia will be astounded for the hundredth time, wondering to itself where the secret sauce is

@owl_posting ask it to draw a pelican on a bicycle and you’ll know

kinda sad that all ai co-scientist platforms refuse to show you what the underlying model is. i trust you to have a good inference harness!! just reassure me that you aren’t using gpt5.1 under the hood!!

Link to post: egbertcastro.com/molecule-reaso…

new blog post! It’s a long overdue dive into the Ether0 reasoning model with a deeper analysis of the GRPO objective in science.

From anthropic.com/research/labor…

expecting life sciences to change a lot by the end of 2026

really impressive lap-in-the-loop fitness landscape navigation work by @tranvinq

link to post: egbertcastro.com/agentic-scienc…

new blog post scientific research in 2026

Faraday can now run background agents. Run multiple experiments in parallel

exciting new capability coming to @AscentBio soon 👀

@devcayer @AscentBio Lets chat!

@AscentBio Would love to give you guys access to our massive small molecule protein datasets to layer in

We are excited to announce that Faraday, our AI scientist for drug design, is now available in public beta. Agentic reasoning. Frontier Models. Seamless code execution. Starting today, researchers and drug developers worldwide can register and begin using Faraday to accelerate their discovery workflows. Public beta is now open at platform.ascentbio.ai

@SGRodriques who’s making the aoe4 fc build order benchmark

It’s so true. The mainstream LLMs still hallucinate like crazy, they’re just way better at hiding it. The other day ChatGPT told me I had to upgrade to gold shaft mining as part of my Lithuanian AoE build, but Lithuanians don’t get gold shaft mining, obviously…

Try it today platform.ascentbio.ai

Today we opened up access to the @AscentBio platform, letting scientists experience what agentic science can be. As a former PhD student, it is exciting to envision an era where researcher productivity can 10x. While not perfect, anyone who’s used Claude code or cursor can see that there’s incredible value in being able to iterate over ideas much quicker. Quality goes up and notably, the pace of progress spikes. In a field where time matters, researchers deserve a tool that can allow for deep domain expertise to be more fully leveraged

anyone building agents for bio should read this

My MD-PhD work is officially out today in Nature Machine Intelligence @NatMachIntell, co-advised by Smita Krishnaswamy @KrishnaswamyLab and Akiko Iwasaki @VirusesImmunity at @Yale. The project centered around multimodal ML for immunogenicity modeling, tweetorial below!