Christoph P. Beier

Patients with IIC and SE have similar rates of PMA, suggesting that IIC could actually be nonconvulsive SE. doi.org/10.1002/epi.70… #epilepsy #ILAE #epilepsiajourn #diffusionrestrictedlesion #EEG #lateralizedperiodicdischarges #periictalMRIabnormalities

We should be moving to ketamine faster for refractory status. In this meta-analysis 1. Response rate was 64% 2. Median maintenance dose 2.5 mg/kg/hr, 3. Dose was the same between responders and non-responders. But... responders were started on KET earlier (3.2 vs 4.3 days) 4. Avg duration of KET 5 days 5. Minimal complications (<1%) #curingcoma neurology.org/doi/10.1212/CP…

Cohort study where we identified 6,295 patients with IGE and 62, 950 normal population controls in the Danish National Patient Register. doi.org/10.1002/epi.70… #epilepsy #ILAE #epilepsia #idiopathicgeneralizedepilepsy #mortality #socialoutcome #statusepilepticus #IGE

Status epilepticus = status epilepticus? Are all status epilepticus equal? No!!! In a population-based study in Denmark, all patients with, for example, juvenile myoclonic epilepsy or other idiopathic generalized epilepsy AND status epilepticus were examined.

This indicate that status epilepticus in IGE patients is a distict disease entity. Read the article in Epilepsia: lnkd.in/eVYr3ph7

All-cause mortality was nevertheless increased, albeit at a low level. The causes of death were all attributable to social disadvantage. These results differ completely from other forms of status epilepticus, which have a mortality rate of over 50%!

Here are our main findings: 📈 Status epilepticus proved to be a disease affecting socially disadvantaged patients. 📊 A status epilepticus episode had no significant impact on social indicators—income and labor market attachment remained unchanged.

Recurrence and Mortality After a First Status Epilepticus: A Retrospective Nationwide Study From the French National Health Data System hubs.ly/Q03pSKJ90 #NeuroX

💡Accurate identification of mimic automatisms can guide clinicians in localizing brain areas involved in seizure onset. Kokkinos et al. provide a great overview! 🔗doi.org/10.1002/epd2.7… @giocastellucci @joanajribeiro @SheikhISMD @SBeniczky @AnphyLab @AlinaIvaniuk

90% of doing science is being open to new ideas.

Status Epilepticus Protocols vary a lot from center to center. In this analysis of protocols from >200 centers, 1/3 did not specify optimal door-to-needle times, and 15% specified doses that are under what is recommended. We need #CodeICH for SE neurology.org/doi/10.1212/WN…

@StruckAF Really interesting paper! Congratulations!

Human Brain Mapping | Neuroimaging Journal | Wiley Online Library onlinelibrary.wiley.com/doi/10.1002/hb… A new article from the JMECP looking at the asymmetric of cortical changes in JME and the relationship with age and cognitive functioning. Does synaptic pruning play a role?

Nyt Nationalt Center for Sundhedsinnovation får hjemme i Odense. Centeret skal sikre, at innovative løsninger og teknologier, der allerede skaber værdi ét sted i landet, hurtigere bliver udbredt til patienter og ansatte på alle landets sygehuse. regionsyddanmark.dk/om-region-sydd…

Tenyi, Horvath, and Jansky report on cenobamate use in Juvenile Myoclonic Epilepsy (JME), showing promising results with a cessation of generalized tonic-clonic seizures. 🔗 doi.org/10.1002/epd2.2… @GiovanniFa83566 @AlinaIvaniuk @SheikhISMD @joanajribeiro @SBeniczky @AnphyLab

We invite you to participate in the #seizure PREDICTION CHALLENGE BASED ON ULTRALONG-TERM #EEG RECORDINGS. For more details, see the links below. epilongcontest.cisuc.uc.pt na.eventscloud.com/website/74027/… #epilepsy @IlaeWeb

Is idiopathic generalized epilepsy preceded by a psychiatric prodrome? jwat.ch/49aaSU9 #epilepsy #NeuroTwitter

We are hiring! Clinical Postdoctoral Associate, Neurology, Yale Epilepsy Center and VA, to work on NORSE/FIRES Studies: details here: postdocs.yale.edu/postdoctoral-a…

Why academia is sleepwalking into self-destruction. My editorial @Brain1878 If you agree with the sentiments please RT. It's important for all our sakes to stop the madness academic.oup.com/brain/issue/14…

Cool study of cEEG in acute liver failure. 40% w/ PEDs, 8% w/ electrographic status. Guess what? That doesn’t predict mortality. What does? Progressive decline in background amplitude and frequency. Just like in cardiac arrest. #curingcoma link.springer.com/article/10.100…