Ernest Iu

microtubules vs actin

Our paper showing that calcium regulates the assembly of lamellipodial actin network is out in Current Biology. Congratulations to Ernest Iu, Alex Bogatch and all authors! It was a great collaboration! sciencedirect.com/science/articl…

Genetically encoded reporters of actin filament organization in living cells and tissues: Cell cell.com/cell/fulltext/…

Excited to share our latest work on how Ca²⁺ regulates actin in cell protrusions - now available as a preprint on bioRxiv! 🎉 Huge congrats to @ernest_iu for leading the project, and a special thanks to our amazing collaborators! biorxiv.org/content/10.110…

Happy to share our latest research article, "The activation of INF2 by Piezo1/Ca2+ is required for mesenchymal-to-amoeboid transition in confined environments," in Current Biology: authors.elsevier.com/a/1koXe3QW8SA2… Graphical abstract:

@nilaytaneja congrats Nilay!

Excited to share my main postdoctoral work in the Zallen lab, now out on Biorxiv! A short thread below for those interested. biorxiv.org/content/10.110…

science.org/doi/10.1126/sc… Just published! We uncovered a molecular machine that connects the cell's two major structural networks revealing how cells accomplish precise internal reorganization - a process disrupted in diseases ranging from cancer to multiple sclerosis.

Jazzed to join the cool kids club and have our paper reporting the reconstitution of zyxin-mediated repair of contractile actin networks appear in @CurrentBiology ! bit.ly/41enkjo

@stevenschem @Penn_CBIO @PennMedicine Congrats Adam!!!

I am excited to announce that in March, I will start my lab in the Department of Cancer Biology (@Penn_CBIO) at the University of Pennsylvania Perelman School of Medicine (@PennMedicine). Stevens.bio

🎉 Great news! Pylustrator, my open-source tool for creating publication-ready @matplotlib plots, works seamlessly with the latest Matplotlib version! 🖌️✨ Curious how it can transform your figures and save your changes as reproducible Python code? Let me show you! 🧵👇

New paper on the role of mDia-family formins in cell cortex function of adherent cells out in @ScienceAdvances ! Huge thanks to Jan 'Hans' Faix for some of the best #STED #Superresolution samples I’ve seen to date. It was pleasure to contribute here. science.org/doi/10.1126/sc…

@Lumba_lab Congrats!

New paper🚨: Ever wonder how plants talk to fungi? When plants are low on phosphate (Pi), they exude #Strigolactones (SLs) in soil to obtain Pi from microbes. We show a broad range of fungi in soil respond to SLs 👇 Is the SL response in fungi conserved? authors.elsevier.com/a/1jsQB3vVUPRm…

Very excited to share the first preprint from my lab! We have developed a biosensor which allows to monitor PTEN activity in living cells, tissue and even whole (small) organisms!! biorxiv.org/content/10.110…

New chromosome paper from the lab of @gwuite lab in Nature materials! 🧬🔬 Beautiful data! 😍 Congratulations to all the authors! nature.com/articles/s4156…

Our latest paper is out! In collaboration with @DrAnneCarpenter, we conducted a systematic high-content screen to understand the role of protein mislocalization in diverse human disorders. 1/ cell.com/cell/fulltext/…

In @JCellBiol, Junior West (@jr2255), Andrew Ewald and colleagues @HopkinsMedicine show that Claudin 7 suppresses #breastcancer invasion and #metastasis. hubs.la/Q02R5NVF0 #Adhesion #Cancer #Migration #motility

Particularly excited to share our latest work, where we visualize how myosin motor forces alter the structure of actin. We discovered a spiral form of the filament which can be recognized by force-sensitive actin binding proteins. biorxiv.org/content/10.110…

@SarahPerlee @whitefishlab congrats!

Thanks to everyone who made this PhD possible! So grateful for my amazing mentor @whitefishlab, committee members, and the entire White lab for all their support these past 5 years! #PhDone

Excited to share our preprint on ERK-mediated dynamic translocation of ZO-1 from tight junction to podosomes during collective cell migration with a talented posdoc Sayuki @SayukiHirano co-supervised by Dr. Ueno @NaotoUENO617516. biorxiv.org/content/10.110…

🧵 Excited to share our latest preprint on bioRxiv: "Actin Dynamics Sustain Spatial Gradients of Membrane Tension in Adherent Cells"! 🚀🧬 In this thread, we dive into the fascinating world of membranes biorxiv.org/content/10.110… #CellBiology #Biophysics 1/12