Erol Demir retweetledi
Erol Demir
1.5K posts

Erol Demir retweetledi

🧵 1/9
As Nephrology Dialysis Transplantation @NDTsocial celebrates 40 years 🎉, a new editorial ✨ highlights how biological sex shapes CV benefits of exercise in CKD.
@VanAmaryllis @olgabalafa @anagarcp #WERA
Read the full article at 🔗academic.oup.com/ndt/advance-ar…
Read the thread for a sneak peek 👇👇 👇

English
Erol Demir retweetledi

🤝 The Developing Education Science and Care for Renal Transplantation in European States Working Group (DESCaRTES) gathered on March 19–20, 2026, for its Annual Meeting to discuss ongoing and future research projects aimed at improving care for patients through education and research, while fostering networking among clinicians and experts in kidney transplant.
📸 Here's a glimpse of the meeting!

English
Erol Demir retweetledi
Erol Demir retweetledi

Kronik böbrek yetmezliği ve böbrek nakli hakkında kısa bir bilgilendirme videosu.
Hastalarımıza faydalı olması umuduyla 🌿 youtu.be/GF6L7ITY0lw #Nefroloji #KBH #BöbrekNakli @yeditepeunihst @KanalD

YouTube
Türkçe
Erol Demir retweetledi

-Kronik böbrek yetmezliği nedir ve neden oluşur?
-Kronik böbrek yetmezliğinin erken belirtileri var mı? Hangi şikayetler dikkate alınmalı?
-Diyabet ve hipertansiyon varlığı kronik böbrek yetmezliği riskini nasıl artırır mı?
Nefroloji Uzmanı Doç. Dr. Erol Demir Kanal D @konustukcatv programında, ‘’Kronik Böbrek Yetmezliği’’ ve Organ Nakline Götüren Süreçler hakkında merak edilen soruları yanıtlıyor.
📌 23.11.2025 Pazar günü gerçekleşecek programı sakın kaçırmayın.
#YeditepeÜniversitesiHastaneleri #BöbrekYetmezliği #BöbrekSağlığı #İçHastalıkları #Nefroloji

Türkçe
Erol Demir retweetledi

Beautiful diagram depicting all aspects of ANCA-Associated Vasculitis (AAV) 🩸
It perfectly shows how:
🔹 PR3-ANCA → GPA — airway & ENT disease, granulomas, relapsing course
🔹 MPO-ANCA → MPA — pulmonary–renal, ILD, neuropathy, higher mortality
🔹 EGPA — eosinophilia, asthma, nasal polyps (often ANCA-negative)
🧭 PR3 = relapsing
⚰️ MPO = severe
🌪️ EGPA = eosinophilic overlap
AAV isn’t three boxes — it’s one evolving spectrum.
#RheumTwitter #MedTwitter #Vasculitis @DrAkhilX @IhabFathiSulima @CelestinoGutirr

English
Erol Demir retweetledi

Erol Demir retweetledi

Now out in @JASN_News
@StefanieSteige6 @PRomagnani
How to Cure Autoimmune GN and podocytopathies
🧐 All autoimmune kidney diseases, no matter what histotype or clinical presentation, benefit from a clone-directed immunotherapy.
▶️journals.lww.com/jasn/abstract/…

English
Erol Demir retweetledi
Erol Demir retweetledi

Erol Demir retweetledi

🫘GLP-1 RA in Metabolic Disease
😬⏬Obesity related complications
doi.org/10.1093/ndt/gf…
@NDTsocial @hjanders_hans

English
Erol Demir retweetledi

The oral GLP !! Orforglipron, an Oral Small-Molecule GLP-1 Receptor Agonist, in Early Type 2 Diabetes | @NEJM nejm.org/doi/full/10.10…
English
Erol Demir retweetledi
Erol Demir retweetledi

#ADA2025: RGT-075 – Oral GLP-1 RA Enters the Ring 💊
Small molecule shows weight loss and BP reduction at 12 weeks
🧪 Phase 2a (n=73; BMI ≥30 or ≥27 + comorbidity)
🧍 Mean WL at 12 wks: −5.4% (RGT-075) vs −0.45% (pbo) – No plateau at 12w
📉 BP ↓:
• Systolic −10.8 mmHg
• Diastolic −4.9 mmHg
🤢 AEs: nausea (40%), vomiting (24%) – mostly mild/mod
🛑 Discontinuation: 4% (same as pbo)✅
👉Oral, non-peptide GLP-1RA with robust metabolic signal
📌 Poster 785-P
#Obesity #GLP1 #OralGLP1 #RGT075



English
Erol Demir retweetledi

#ADA2025: Eloralintide Enters the Chat 💬
New long-acting amylin receptor agonist (Elora, QW 💉) shows early promise for obesity
📊 Phase 1 (n=100, BMI 27–43)
• Mean weight ↓ at 12wks: −2.6% to −11.3%
• t½ ~14–16 days
• PK exposure dose-proportional
🤢 GI AEs:
• Diarrhoea 10%
• Nausea 8%
• Vomiting 4%
🧠 Other AEs: ↓appetite (19%), headache (12%), fatigue (11%)
🛑 1 SAE (unrelated), 0 deaths
🔁 QW Elora well tolerated. Phase 2 next. Another amylin angle after Cagri?
🔗 ADA 882-P –2025
#Obesity #Amylin #Eloralintide #GLP1adjacent #ADA2025




English
Erol Demir retweetledi

Obesity accelerates cardiovascular ageing
This review evaluates the intricate interplay between obesity and ageing from molecular mechanisms to whole organ function within the cardiovascular system
academic.oup.com/eurheartj/arti…

English
Erol Demir retweetledi

Erol Demir retweetledi




















