GoggleDocs retweetledi
GoggleDocs
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GoggleDocs
@GoggleDocs
🥽🩺Docs/nurses/pharmacists from U.K. Talking CardioRenoMetabolic & more Catch us on YouTube https://t.co/VSFSwEDXDD |Educate, Motivate, Activate!
London, England Katılım Ekim 2020
2.9K Takip Edilen3.8K Takipçiler
GoggleDocs retweetledi
¿Cuándo elegir semaglutida y cuándo tirzepatida?
La EASO acaba de actualizar su algoritmo con evidencia hasta noviembre 2025 📊 @EASOobesity
Spoiler: depende del objetivo clínico. No es solo pérdida de peso.
🔗 @NatureMedicine
nature.com/articles/s4159…
#ECO2026
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GoggleDocs retweetledi
Interesting data from #ECO2026 @EASOobesity
Building on the need for more data in women’s health esp around menopause but more interesting is the migraine data
Expanding the other potential beneficial effects of weight loss and why there are also trials in IIH with incretins
Novo Nordisk@novonordisk
#PRESS Our new data presented at the European Congress on Obesity highlights the powerful, consistent weight loss that our obesity injection delivers for women across all menopause stages. The data reveals that it also lowers risk of migraine, depression and cardiovascular disease, highlighting the broad support our medicine provides for women living with obesity. Learn more in the press release here: novonordisk.com/content/nncorp…
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GoggleDocs retweetledi
🔥My latest Medscape Primary Care #Hack is live!
💡Continuous Glucose Monitoring #CGM for people living with #T2D
Co-authored with @drheatherbell
Includes 8 simple steps to interpreting the Ambulatory Glucose Profile report #AGP
PDF download link in comments 👇
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GoggleDocs retweetledi
Don’t miss the signs of #T1Diabetes
The 4 Ts
And no, they don’t have to be altogether as a presentation
Keep this in your mind as a possible diagnosis
Even one life saved?
Is worth all the “cost”
Better safe than sorry
#T1Diabetes 💙
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@Andy_Ross1962 @TheMeldrew lots of noise coming from the airport, although nothing on flightradar 24
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@TheMeldrew There was a big exercise on over the North Sea yesterday and today.
Draken Europe at Teesside Airport near me provide electronic countermeasure and aggressor training to the RAF using a fleet of Dassault Falcon 20 and Aero L-159E fighters.
They were all out yesterday
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Just had 3 Typhoon jets over, what a sound
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GoggleDocs retweetledi
Check out our latest @GoggleDocs NICE summary - Semaglutide 2.4mg in ASCVD
@DrDerekConnolly @escardio @ATTDconf @EASDelearning @banshisaboo @dramitaol @AskDrShashank @hvanspall @BrJCardiol @ABCDiab @NICEComms
GoggleDocs@GoggleDocs
🚨NICE TA1152: #semaglutide 2.4 mg recommended as an option for ⤵️💔risk in adults with established CVD and BMI ≥27 kg/m² 🚨 🔹 Eligible: previous MI, ischaemic/haemorrhagic stroke, or symptomatic PAD, with BMI ≥27. No restriction on time since index event. T2D not excluded. 🔸 SELECT (n=17,604): First MACE: HR 0.80 (0.72-0.90) Non-fatal MI: HR 0.72 (0.61-0.85) Coronary revasc: HR 0.77 (0.68-0.87) All-cause death: HR 0.81 (0.71-0.93) Benefit appeared early, before substantial weight loss. 🔹 Preferred ICERs £6,878 to £14,594 per QALY, well below the £20,000 threshold. 🔸 What a TA means for access: statutory funding mandate. ICBs in England must make it available within 90 days when considered the right treatment (Wales: 60 days from final draft). But that doesn't mean immediate primary care prescribing. 🔗 nice.org.uk/guidance/ta1152 #PrimaryCare #Cardiology #GLP1 #NICE
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So folks: this means that if you have obesity…. You are 38% less likely to die if you have bariatric surgery - there are no studies for GLP-1ra that show these dramatic results.
Neil Floch MD@NeilFlochMD
There is a 38% less likelihood of mortality with bariatric surgery than with GLP-ra treatment. #ASMBS2026 as presented by Dr Ali Arminian
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🚨NICE TA1152: #semaglutide 2.4 mg recommended as an option for ⤵️💔risk in adults with established CVD and BMI ≥27 kg/m² 🚨
🔹 Eligible: previous MI, ischaemic/haemorrhagic stroke, or symptomatic PAD, with BMI ≥27. No restriction on time since index event. T2D not excluded.
🔸 SELECT (n=17,604): First MACE: HR 0.80 (0.72-0.90) Non-fatal MI: HR 0.72 (0.61-0.85) Coronary revasc: HR 0.77 (0.68-0.87) All-cause death: HR 0.81 (0.71-0.93) Benefit appeared early, before substantial weight loss.
🔹 Preferred ICERs £6,878 to £14,594 per QALY, well below the £20,000 threshold.
🔸 What a TA means for access: statutory funding mandate. ICBs in England must make it available within 90 days when considered the right treatment (Wales: 60 days from final draft). But that doesn't mean immediate primary care prescribing.
🔗 nice.org.uk/guidance/ta1152
#PrimaryCare #Cardiology #GLP1 #NICE
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GoggleDocs retweetledi
Farage and the dodgy £5m donation finally gets a mention on the BBC but still not a single word on a single front page.
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Victoria Derbyshire spend 8 minutes taking apart Nigel Farage's £5,000,000 gift
"As you'd expect we asked Reform UK for an interview tonight. One Reform UK press officer asked: with who and to discuss what"
"We said we'd like to talk about the local elections, the detention centres in Green areas, and £5m gift from Christopher Harborne"
"We didn't receive another reply"
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GoggleDocs retweetledi
In the words of the man himself… @mbrp1
What exactly is the comic book series around living with #T1D about?
Thank you @PComicCon for hosting us 🙂
Do listen, read & cascade as you can
@triggersbroom17 @BT1DUK @DRWFDiabetes @DiabetesUK @mrmarkmillar
Link- (free to download):
Via @RevolveComics
revolvecomics.com/read-diabetes-…
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Apologies if anyone got some random DM from me I was hacked!!!!
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🍷 First RCT of semaglutide 2.4mg in treatment-seeking patients with alcohol use disorder + obesity
n=108
26 weeks
semaglutide + CBT vs placebo + CBT
Primary endpoint (% heavy drinking days):
🔹 Semaglutide: -41.1pp
🔸 Placebo: -26.4pp
🔹 Difference: -13.7pp (p=0.0015)
Secondary endpoints consistent: total alcohol intake, drinks per drinking day, WHO risk level, craving all favoured semaglutide. Phosphatidyl ethanol supported self-report.
Safety: GI AEs higher (nausea 57% vs 7%). 4 vs 1 discontinued for AEs. No pancreatitis.
Caveats: BMI ≥30 only, single centre, no post-trial follow-up. Weight loss correlated with drinking reduction (ρ=-0.40).
Moves beyond hypothesis-generating. Replication needed before off-label use.
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GoggleDocs retweetledi
Sleep and metabolism are tightly linked.
🛌 ~7.3 hrs = optimal insulin sensitivity -oh dear 😔
📈 Too little sleep → worse insulin resistance
📉 Too much sleep → also harmful
🔄 Weekend catch-up helps only if sleep-deprived (1–2 hrs), but >2 hrs may backfire
Personalised sleep matters for metabolic health.
drc.bmj.com/content/14/2/e…
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GoggleDocs retweetledi
Review: Metabolic liver disease: A summary of major guidelines and identifying opportunities to improve future guidelines
dom-pubs.onlinelibrary.wiley.com/doi/epdf/10.11…
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#type2diabetes #Obesity
🔬 A quintuple agonist combining GLP-1R/GIPR co-agonism with pan-PPAR agonism (α/γ/δ) in a single molecule.
🎯delivery of lanifibranor at ~6,900x lower dose than standalone.
✅Outperformed semaglutide and dual agonism in DIO 🐁. Glycaemic benefit partly weight-independent.
Preclinical. But the approach is worth 👀
#GoggleDocs review
🔗 doi.org/10.1038/s41586…
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"Our patients don't live in silos. It's time we stopped working in them."
📢TONIGHT 7pm. Free webinar with @drkevinfernando launching The CKM Collaborative.
Cardiovascular. Kidney. Metabolic.
One story.
Still time to join the 100+ registered
💻 tinyurl.com/3hszjs5s
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GoggleDocs retweetledi
Delighted to be in Accra Ghana with @scelee1
Launch of our Trilogy of papers on Diabetes in Africa in @TheLancetEndo 👇
Its been an honour co-ordinating these 3 papers with a wonderful global colleagues
sciencedirect.com/science/articl…
sciencedirect.com/science/articl…
sciencedirect.com/science/articl…
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