Evan Appleton

@officialMaxRye @LabCentral @c10labs Looking forward to building Intertwined Biosciences with you and Jenhan Tao - it's going to be an exciting journey!

Intertwined Biosciences is out of stealth 🚀 We're harnessing evolution to build regenerative therapeutics using AI-native discovery. Just admitted to @LabCentral AI BioHub w/ @C10Labs. First experiments live. Raising pre-seed. DM if you're at the intersection of AI x bio

ML-guided cell-fate engineering cell.com/callback?red_u…

Excited to welcome @evappleton from @colossal as a featured speaker!

If you're in the Boston area - come join us for the Engineering Biology Club next Thursday, October 3! hubs.la/Q02Rd-9Y0

CAD software for designing multicellular shapes from a single cell progenitor finally published! pubs.acs.org/doi/10.1021/ac…

Interested in Generative AI for BIO? Please Join George Church, David Baker and Sarah Carter for an interactive SynBioBeta Town Hall on "Generative AI for Protein Design: Balancing Risks with Opportunities". Tuesday Apr 16th at 12 noon pacific. You can register here: synbiobeta.zoom.us/webinar/regist…

Our Woolly Mammoth team has achieved a global-first iPSC breakthrough! 🏆 iPSC cells represent a single cell source that can propagate indefinitely and elephant iPSCs (the most elusive iPSCs to date) are now obtainable! #bioscience #deextinction #technology

biorxiv.org/content/10.110… Elephant induced pluripotent stem cells

@svheeringen @svheeringen Our bad if we missed some more recent papers! If you DM me some more references, we will be sure to qualify our statements more in review!

Great to see @geochurch becoming a developmental biologist (it's never too late) Systematic identification of txn factor receipes for cell fate reprogramming biorxiv.org/content/10.110…

Cell-Cell adhesion work out in the journal..."Cell." A perfect fit! doi.org/10.1016/j.cell…

Creating programmable cellular assembly via orthogonal cell-surface binding proteins just published: cell.com/cell/fulltext/…

Our work developing a protein-based delivery system was just published! cell.com/cell-reports/f…

Lattice Automation is #hiring! We are looking for a #productmanager to be part of a team focused on delivering cutting edge #software solutions: linkedin.com/posts/lattice-…

Our group (led by Prof. @DouglasDensmore) is #hiring a Research Systems Engineer II to maintain and develop computational tools and manage IT systems for #microfluidics, lab #automation, and #synbio. Check out the post here: bu.silkroad.com/epostings/inde…

Paul Nurse, who won a Nobel for his work on the cell cycle, calls for more daring theory in biology and criticizes current trends in large scale data generation. We probably need to reimagine the Discussion section of papers! nature.com/articles/d4158…

In work led by @StorkDevon & in collaboration between @fleshball & @geochurch, we report site-specific incorporation of a variety of non-standard amino acids in Bacillus subtilis for several purposes including interrogation of bacterial cytokinesis. Now out in @NatureComms (1/2)

With $15 million in private funding, a new company called Colossal is trying to edit elephant DNA to genetically resurrect the woolly mammoth, thousands of years after it went extinct. nyti.ms/3nuA6GU

A paper I authored discussing current technical aspects of biosecurity was recently published as a chapter in the book: Emerging Threats of Synthetic Biology and Biotechnology link.springer.com/chapter/10.100…

Our review of Cell Therapy Strategies for COVID-19 was just published! advances.sciencemag.org/content/7/33/e…