Stephen Fried JHU
1.2K posts
@fried_lab
Assoc. Prof of Chemistry🧪 & Biophysics @JohnsHopkins; we ❤️ proteins; unofficial lab rabbi ✡️; 🏳️🌈; #TeamMassSpec.
#FriedLabNews time! Dec-Jan was busy with lots of graduations & @fried_lab alums are off to great things! @haleymoran23 is headed to @berkeleyMCB @MarquseeLab; @_divyayadav is headed to @StJudeResearch O’Reilly lab; April to @EliLillyandCo & Edgar to lead proteomics @HHMIJanelia
Ever wondered who the real rockstars of R01s from the past 5 years? We ranked the most funded PIs in cancer R01s from 2020–2024. Anyone with persistent effort can (maybe) win one R01. Winning 38–48 of them over 5 years is something else entirely. R01s flow towards people whose ideas repeatedly translate into durable programs. Durability means: • hypotheses that age well • biology that generalizes • institutions that trust you with long arcs • and ideas NIH is willing to underwrite repeatedly ======== Meet the rockstars, their institutions, and an examplary funded research: Allen Gao (University of California, Davis @ucdavis) 48 R01 awards | $14.6M Sample Award: 5R01CA271327 Novel therapeutics dual targeting intracrine androgen synthesis and AR for advanced prostate cancer Xiaoqi Liu (University of Kentucky @universityofky ) 46 R01 awards | $20.3M Sample Award: 5R01CA272483-03 Targeting the PLK1/PDCD4/mTORC2 signaling to treat castration-resistant prostate cancer Tim Rebbeck (Dana-Farber Cancer Institute @DanaFarber) 43 R01 awards | $10.4M Sample Award: 5R01CA259200 Genetic and genomic variation in prostate cancer Shoujiang Gao (University of Pittsburgh School of Medicine @PittTweet) 42 R01 awards | $21.3M Sample Award: 5R01CA284554 Impact of microbiota on AIDS-Kaposi’s sarcoma development and therapy James Basilion (Case Western Reserve University School of Medicine @cwru) 39 R01 awards | $18.2M Sample Award: 5R01CA255925 Highly selective targeted theranostics for prostate cancers Binghui Shen (City of Hope Beckman Research Institute @cityofhope) 39 R01 awards | $16.6M Sample Award: 5R01CA233664 DNA repair gene mutations and prostate cancer Daniela Bota (UC Irvine @UCIMedSchool) 39 R01 awards | $10.4M Sample Award: 5R01CA263806 Targeting p38/JNK MAPK to ameliorate cisplatin-induced adverse sequelae on the nervous system Nan Hao (UC San Diego @UCSDMedSchool) 38 R01 awards | $17.1M Sample Award: 1R01AG086348 Engineered genetic clocks for control of cellular aging Zhenghe Wang (Case Western Reserve University School of Medicine @cwru) 38 R01 awards | $16.8M Sample Award: 4R01CA260629 Role of PTPRT in colon cancer progression and metastasis Tony Faber (Virginia Commonwealth University School of Medicine) 38 R01 awards | $16.6M Sample Award: 5R01CA276207 MYCN drives a ferroptotic vulnerability in neuroblastoma
Both chambers of Congress have now passed the FY26 minibus with NIH provisions. The President will sign. (1) $48.7 billion for NIH (2) Full IDC recovery (3) No more multi-year funding (4) No NIH reorganization, maintaining the current IC structure.
