Frothferous

510 posts

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Frothferous

Frothferous

@frothferous

Part-time thinker and everything else

Columbia MO Katılım Ağustos 2017
97 Takip Edilen10 Takipçiler
Frothferous
Frothferous@frothferous·
@JesslovesMJK @mattwridley For DNA engineering, one would presumably use codon optimization so as not to introduce GC rich region(s). Here's the furin RNA sequence in question: "CCTCGGCGGGCA" If you were engineering the amino acid sequence, you would not use those codons.
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Jessica Rose 🤙
Jessica Rose 🤙@JesslovesMJK·
@mattwridley Well actually, to be perfectly accurate, other viruses do have furin cleavage sites but NONE with the PRRAR specific site. That's because it was made in a lab using recombination techniques.
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Matt Ridley
Matt Ridley@mattwridley·
I have been told someone found my lecture persuasive until they spoke to a virologist who said: "lots of viruses have furin cleavage sites". Repeat after me, slowly: SARS-COV-2 IS THE ONLY SARBECOVIRUS EVER FOUND WITH A FURIN CLEAVAGE SITE. OUT OF SEVERAL HUNDRED STRAINS.
Matt Ridley tweet media
Matt Ridley@mattwridley

In my lecture at @NIH, at the invitation of @NIHDirector_Jay, I explained why I changed my mind from thinking the lab leak theory of covid origins was unlikely to thinking it was almost certainly true. Please watch and assess the evidence yourself. videocast.nih.gov/watch/244438a5…

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Tyler Stepke
Tyler Stepke@TylerAStepke·
SARS-CoV-2 is the only sarbecovirus ever found with an FCS. The idea to insert an FCS into sarbecoviruses in 2018 was inspired by the natural occurrence of FCS in more distant viruses. The dangerous bias of many virologists is no longer surprising. I'm unsure if any scientific field has been as thoroughly disgraced as modern virology, which is deeply tragic given the critical importance of the field to the health of our species. It will take decades to repair and rebuild trust with the public.
Matt Ridley@mattwridley

I have been told someone found my lecture persuasive until they spoke to a virologist who said: "lots of viruses have furin cleavage sites". Repeat after me, slowly: SARS-COV-2 IS THE ONLY SARBECOVIRUS EVER FOUND WITH A FURIN CLEAVAGE SITE. OUT OF SEVERAL HUNDRED STRAINS.

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herculez gomez
herculez gomez@herculezg·
Timothy Weah was essentially told to “shut up and dribble” by his #USMNT manager Mauricio Pochettino after he spoke out against outrageous World Cup ticket prices. Here he is at Zohran Mamdani’s affordable tickets press conference.
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Frothferous
Frothferous@frothferous·
@DrGerryParker “the predominance of circumstantial evidence strongly points toward a lab incident” oh do tell, “Dr.”
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Dr. Gerald Parker
Dr. Gerald Parker@DrGerryParker·
The origin of covid is a nonpartisan issue. It has become obvious to those without a conflict of interest that the predominance of circumstantial evidence strongly points toward a lab incident, again this is nonpartisan. I understand some disagree, but there should be no disagreement that the US must now lead with diplomacy to establish enforceable international biosafety and biosecurity standards and regulations/safeguards - especially for dangerous dual use dGOF research.
Senator Ashley Moody@SenAshleyMoody

Jarring to witness not a single Democrat participate in today’s hearing. Clearly, they do not care about what happened under their leadership during COVID.

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Frothferous
Frothferous@frothferous·
@dilanesper The process that led us to the current iteration of the Supreme Court is inferior and less democratic than any other system ever conceived. The notion that the court is an “independent judiciary” is incredibly naive. See Alito on any topic.
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Dilan Esper
Dilan Esper@dilanesper·
This is obviously demagoguery, but to be clear, packing the Court to 13 Justices would destroy the independent judiciary and make the courts the political tool of whoever won the last electoral trifecta, while sending the rest of US law into chaos.
Rep. Ro Khanna@RepRoKhanna

The Supreme Court has engaged in an ugly recidivism that has marked the fastest rollback of Black political rights since Reconstruction. 18 year terms limits on Justices now. Expand the court from 9 to 13 Justices now.

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Frothferous
Frothferous@frothferous·
@JonahDispatch Goldberg demands deep skepticism of any state that claims to use absolute power for a righteous cause. Yet, when analyzing Israel, he defends their official narratives at face value, and dismisses all whistleblowers as bad actors—the exact playbook he warns against in his book.
Frothferous tweet media
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Jonah Goldberg
Jonah Goldberg@JonahDispatch·
This will end with ruined careers and reputations, and deservedly so. May take a while though.
Jonah Goldberg tweet media
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Frothferous
Frothferous@frothferous·
@MattZeitlin Totally insane his Middle East/foreign policy numbers are in the low 40s. Should be single digits in a proper country.
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Frothferous
Frothferous@frothferous·
@BBKogan Sing it brother...it was a corporate tax cut that triggered the Boston Tea Party!
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Frothferous
Frothferous@frothferous·
@SouthernKeeks I think most people find this maudlin performance hypocritical. As a lawmaker Sasse voted for and helped shape the economy in a way that enriched corporations and hollowed out the working class, whom he now berates for their lack of participation in his idealized social contract
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Kimberly Ross
Kimberly Ross@SouthernKeeks·
Imagine missing the point of what he’s saying about technological distraction and the erosion of focus across almost every area of modern life.
Kimberly Ross tweet media
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Frothferous
Frothferous@frothferous·
@mattyglesias 2020 was not a favorable Republican climate, yet Collins handily beats Sara Gideon (the centrist Dem candidate). Mills (the centrist Dem choice) was not going to beat Collins. Make of that what you will, but you should adjust your priors accordingly.
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Frothferous
Frothferous@frothferous·
@churrascooooo This individual has a PhD from Yale, served in the Dept. of Health and Human Services and argued the status quo pre-ACA was preferable to the ACA. After a decade of similar votes he was rewarded with a no show UF President gig, and enriched his buddies.alligator.org/article/2024/0…
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Frothferous
Frothferous@frothferous·
@mattyglesias look at the R2, the model fits pretty nicely! What it misses is outcomes, i.e. are we healthier than lower spenders? I think the answer is fairly clear we are not. So the question is what are we spending on that doesn't improve health outcomes.
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Frothferous
Frothferous@frothferous·
@Rightanglenews As it should be, one person one vote is hard to argue against. The electoral college disproportionately weights the vote of individuals from smaller states.
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Right Angle News Network
Right Angle News Network@Rightanglenews·
BREAKING - Outrage is erupting across Virginia after Abigail Spanberger signed HB965 into law, effectively rendering Virginians’ presidential votes null and void, with the measure handing the states electoral votes to the national popular vote winner regardless of states results.
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ThePersistence
ThePersistence@ScottPresler·
Thank you for having me back, @Timcast. See you tonight on Timcast IRL @ 8 p.m.
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Frothferous
Frothferous@frothferous·
@DavidD_Chapman lol, constitution says what, who cares I’m David Chapman. Like my analysis on international affairs, wait until you hear about my ideas about mRNA. Not in my body mutant molecule!
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David D. Chapman
David D. Chapman@DavidD_Chapman·
Do you know the last time Congress formally declared War? June 1942. Wars since 1942 Korea Vietnam Gulf War Iraq Afghanistan Syria ISIS War on Terror The US President can absolutely carry out military action without congressional approval. Stop pretending otherwise.
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Frothferous
Frothferous@frothferous·
@ScottJenningsKY Love that this guy relinquished all his principles for Trump, a pathological liar whose motivations are solely corruption and vanity.
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Scott Jennings
Scott Jennings@ScottJenningsKY·
🚨🚨Senior Trump Administration officials telling me that credible intelligence indicated Iran planned preemptive missile strikes against US military targets in the region, and against civilian targets as well. Failure to act would’ve resulted in mass US casualties.
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Frothferous
Frothferous@frothferous·
@JCPolancoNYC He got the federal government to fund housing starts in his city, what’s not to like?
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Keşfet

@JesslovesMJK @mattwridley @TylerAStepke @herculezg @DrGerryParker @dilanesper @JonahDispatch @MattZeitlin