fruiting body

@pratyushbuddiga DFW hits at this in his This is Water commencement speech so damn well

He's just like me fr

@coldhealing Trader Joe's

Going to the grocery in my yuppie neighborhood during my wfh lunch break. I am in line behind two wasian babbies pushed around in a double stroller by their person of color nanny. This is water

How should I make $600 to pay for 30x sequencing of my whole genome?

@crisprspace aren't you checking the whole genomic medicine sector? lots of macro stuff driving prices

This is why I call $PRME a clown stock now. Thanks to the management.

Nothing ever happens man war.gov/UFO/

If we could live forever the marginal value of time would collapse to nothing and we'd be dead anyway

Garry Nolan said there was going to be a "huge announcement" in the next couple of days related to UFOs

@DontAskJeeves13 @Michaeldudufudu @mattforney PhD?

@Michaeldudufudu @mattforney You have no idea how hard it is to get hired into big pharma as a straight white man. Took me almost a 30 interviews with a dozen companies

Because we dont get free jewish daycare

@shaggysurvives Like, Scoob, when everyone's a stoner no one's a stoner. "Rhes Rhaggy"

legalizing weed killed stoner culture. nowadays everyone smokes weed no ones a stoner

@kenbwork good stuff. does latch have stuff for multiplexed tissue imaging like CODEX, 4i, IMC, etc?

Gave a talk to Machine Learning @ Berkeley on benchmarking frontier models on spatial biology. Why understanding how assays work is important, what verifiability might look like with messy biology + infrastructure challenges running agentic evals at scale.

I'm surprised that 1/3 accounts on polymarket are profitable. I would've expected far less with the conventional wisdom that "99% of day traders are unprofitable"

@kenbwork Do mutations *affect* autism development. I view grammatical errors as proof of human in text but maybe not images. I know historically Latch has published AI hallucinated citations

Have learned a lot building and deploying frontier agents into pharma over the past few months. Believe progress in biotech will be faster than many anticipate, and we can learn a lot from how software is unfolding. It’s unlikely biology will jump straight to fully autonomous AI scientists. Like software, agents first get useful where work is executable, feedback-rich, and economically bottlenecked. In software, that substrate is code. In biology, it is measurement-grounded data analysis. As agents reliably turn raw molecular data into trusted scientific outputs, they become the interface through which AI starts to understand biology. Essay below:

I came back to the United States, hearing about a very sad news: Craig Venter passed away today. He is a pioneer, successfully sequenced the first Human genome, and tried to create Synthetic Cells. We lost a giant in Science. RIP. @JCVenterInst

@emukamel True

@fruit_struck Thats true (hence more common to see nuclear snRNAseq in brain) but if that is the explanation here then the expt is incompetent.

I can't understand why this "mouse brain scRNA" data contains neuroblasts and Purkinje cells (?!) but not other types of neurons? If they included cerebellum there should be lots of granule cells, and very few Purkinjes.... Something seems off here

What do you mean? Doing scRNA-seq requires dissociating tissue into single-cell suspension. Mature brain tissue is difficult to dissociate because it's highly myelinated and requires mechanical force to break up. Delicate cell populations like neurons get destroyed and underrepresented as a result.

@fruit_struck Huh?? That makes no sense, sorry

If you cannot schizopost at all you should be concerned no proof of life is anything even going on in your head

@HusbandTrad Tough

Still no word on this new job. I’m waiting to hear back but genuinely stunned. 10 years of experience, literally doing a 1:1 of the exact job just at a different company. 2 interviews went extremely well, I’m just at a loss for what the logic here is

@mudscryer No (echo)

Guys do I come across as an empath