GEFSES_CREATE

The 2025 GEFSES International Symposium is currently underway at the Punjab Agricultural University. @JaswinderMcGill @McGill_VPRI @NSERC_CRSNG @CropLifeCanada

🥣🧬 This breakthrough (first edit of oat DNA) could help oat farmers boost yields, reducing reliance on chemicals used to speed up harvests.⤵️ The study received #NSERCsupport. (@NSERC_CREATE Program on Genome Editing for Food Security and Environmental Sustainability, GEFSES).

Congratulations to @JaswinderMcGill on being selected for the prestigious Mary E. Spencer award by the Canadian Society of Plant Biologists, in recognition of his outstanding research contributions & engagement in the plant biology community! mcgill.ca/x/ig2

I am so excited to share our report on the first-ever successful CRISPR/Cas9-based gene-editing in oats, now published in the Plant Biotechnology Journal. Kudos to the Singh Lab (@JaswinderMcGill). Honoured to have it as a part of my PhD research. Link: doi.org/10.1111/pbi.70…

Daniel Getts and co-workers @MyeloidTx present CRISPR-Enabled Autonomous Transposable Element (CREATE), a #genome editing system that combines #CRISPR/Cas9 with a modified LINE-1 retrotransposon machinery, for #RNA-based #gene editing and delivery. embopress.org/doi/full/10.10…

🧬 New-gen genome editors with potentially higher fidelity and capable of longer edits are here! Think prime editing but with DNA-dependent DNA polymerases instead of a RT. A comparison of recent tools from @ESontheimerLab & @BKleinstiver Lab. Thread 🧵:

📣Are you interested in gene editing 🧬 work in plants 🌱? Dr. Singh's Lab(@JaswinderMcGill ) at McGill University has one Postdoctoral position open for application. See below for details 👇.

Exciting times ahead for wheat farming! 🌾🔬Canada’s first #GeneEdited wheat trial is set to be conducted this year, and may find ways to make our favourite grain even more resilient. See how this project will flour-ish at: brnw.ch/21wNXRY

Dr. Zhou, a GEFSES trainee at @JaswinderMcGill lab, has published his findings in the Journal of Plant Biotechnology, stating that oats can become more nutritious and increase their shelf life using genetic engineering techniques.@McGill_VPRI, @NSERC_CRSNG @CropLifeCanada

Congratulations ! to Zhou for his first-author paper on metabolic engineering in oat @JaswinderMcGill Lab Plant Biotechnology Journal @McGillMacCampus @PlantMcGill @McGill_VPRI @OatNewsletter @USDA onlinelibrary.wiley.com/doi/full/10.11…

Delighted to try out the world’s first CRISPR-edited salad from Conscious Foods and @PairwisePL. Mustard greens were edited with Cpf1/Cas12a to reduce their spiciness while retaining their nutritional content (which is 2X better than romaine lettuce). 🙏 @zhangf for the invite

Our lab as well as students in the class I teach this semester enjoyed tasting the first CRISPR-edited salad greens, in which the myrosinase gene that results in the pungency of raw mustard greens (Brassica juncea) has been disabled, yielding a nutrient-dense, tasty, and attractive, salad without the ‘mustard bomb’. Thank you @PairwisePL for providing the samples! The science behind the greens: mdpi.com/2223-7747/11/1… Disclosure: I am a cofounder of Pairwise Plants along with @JKeithJoung and @zhangf.

* The CARBON Newsletter is back with the latest news on CRISPR in agriculture * In this edition you can read about a new optimised prime editing system for tomatoes, wheat with 97.7% reductions in gluten and much more. It's all availble for you from CRISPR Medicine News' website 👇 lnkd.in/dfWtCUvi #crisprmedicinenews #carbon #crispr #geneediting #genomeediting #plants #agriculture P

A new chapter for genome editing: RNA-guided recombinase enzymes have been discovered that enable the programmable insertion, inversion or deletion of long DNA sequences go.nature.com/3RHgWMA

Research| @RIKEN_IMS team developed a gene-editing technique for marmosets, modeling Alzheimer’s disease, using TALEN to introduce heterozygous exon skipping mutations. #GeneEditing Link: 👇 nature.com/articles/s4168…

🌾 In Europe's first-ever field trial of gene-edited wheat, scientists have successfully reduced a potential carcinogen in wheat crops by using the #GeneEditing tool, #CRISPR! Knead to know more? 🍞 Visit: brnw.ch/21wMsIE

The 2024 GEFSES Summer Workshop was a great way to reconvene great minds with a common interest in CRISPR-Cas-assisted agricultural development and environmental sustainability. We appreciate all the participants (in-person and online) and those who organized this workshop!

Upcoming Webinar! Dr. Jaswinder Singh will discuss some of the findings of the @gefses_create program. @McGill_VPRI @NSERC_CRSNG @CropLifeCanada

GEFSES student Mehtab Singh, #HexaploidSingh, gave an excellent presentation on “SUSTAINABILITY THROUGH SCIENCE SYMPOSIUM.” @McGillMacCampus @PlantMcGill @JaswinderMcGill @NSERC_CRSNG @OatGrowers