Nephi Walton

This is really quite remarkable in terms of understanding the origin of several human genetic disorders. nature.com/articles/s4146…

I should add, that I was so impressed that I ended up buying one two weeks later and we used it for the project. FSD has been great for me too. I actually just relax and communicate with Grok about genetic conditions I am seeing as the car is driving me to work. Driving is much less painful than it used to be. My thought was that if they approved her to drive with FSD that I would hand over the keys, but she might have to get her own Tesla (with some help).

I think the use of FSD for people with disabilities has tremendous potential. Nearly 3 years ago, we discovered my daughter had epilepsy, she has not had a tonic clonic seizure since but continues to have small myoclonic jerks of her hands once or twice a day that last less than 2 seconds. These can be embarrassing and she drops things occasionally when this happens. As she is 15 and turning 16 soon, the biggest questions she has had at each appointment is "when can I drive". After an appointment in December she was very discouraged with no answer as to when she could drive. To lighten her mood I took her to a Tesla dealership and we test drove FSD (technically the car drove the whole time). This made her extremely happy as she could see that some day regardless of her seizure control she would be able to drive. This inspired her entry into the Presidential AI competition for which her team won in the state of Utah. She thinks, and I agree, that FSD could be prescribed by clinicians to help people with epilepsy like hers gain independence today, but could be even better if other features were integrated into Tesla’s internal camera system. @Tesla and @elonmusk would love to have your thoughts on this. She is going to continue working on this even if she does not win regionals, because it is extremely important to her.

Grok and Tesla FSD are literally saving lives Here are the two real live stories from 2026: ➝ A man had a massive heart attack driving. His son remotely activated FSD, set hospital as destination...the car got him there safely as he collapsed. Every second counted ➝ Another man endured 24 hours of severe pain. He described his symptoms to Grok, who immediately flagged a near-ruptured appendix and urged him to go back for a CT scan. The scan confirmed it; emergency. Surgery removed the appendix just in time Elon: "Upload X-rays/MRIs to Grok....it diagnoses better than some docs. FSD saves lives in emergencies, driving you to hospital" Tesla’s Full Self-Driving and Grok are already saving real human lives

@EdwardLawr82368 @XFreeze Yes, my daughter actually brought that up in one of her presentations

@geneticks @XFreeze And don’t forget senior citizens!

Nearly 3 years ago, we discovered my daughter had epilepsy, she has not had a tonic clonic seizure since but continues to have small myoclonic jerks of her hands once or twice a day that last less than 2 seconds. These can be embarrassing and she drops things occasionally when this happens. As she is 15 and turning 16 soon, the biggest questions she has had at each appointment is "when can I drive". After an appointment in December she was very discouraged with no answer as to when she could drive. To lighten her mood I took her to a Tesla dealership and we test drove FSD (technically the car drove the whole time). This made her extremely happy as she could see that some day regardless of her seizure control she would be able to drive. This inspired her entry into the Presidential AI competition for which her team won in the state of Utah. She thinks, and I agree, that FSD could be prescribed by clinicians to help people with epilepsy like hers gain independence today, but could be even better if other features were integrated into Tesla’s internal camera system. @Tesla and @elonmusk would love to have your thoughts on this. She is going to continue working on this even if she does not win regionals, because it is extremely important to her.

My daughter animating her Easter eggs with Grok Imagine

Witnesses Testify on FDA Regulations and Innovation c-span.org/program/senate… As a clinician who cares for patients with these disorders, I am deeply troubled by recent FDA actions. While there has been some encouraging news, it has not translated into meaningful progress. Many of these patients—particularly those with spinocerebellar ataxia—are losing function every day that they will never regain, even as therapies with demonstrated positive effects exist but remain out of reach. This is not a political issue. It is profoundly frustrating to watch patients deteriorate rapidly when a potentially beneficial intervention exists, yet incomprehensible regulatory barriers continue to delay access.

Grok is very good. I’m a clinical geneticist and I’m seeing more and more patients come up with correct diagnoses using LLM’s. In several cases they are trying to get genetic testing from a specialist who brushes them off. For those, it’s making them lose faith in the medical system when they feel they have more information than their provider. We have to embrace AI as clinicians or risk losing the trust of our patients. For my field it’s impossible for me to memorize the 10,000 plus diagnoses I see. For a computer this is trivial. Physicians still have value exceeding LLM’s for patient care, but we need to recognize with humility where AI beats us and utilize it rather than shun it, anyone who doesn’t will become obsolete.

Grok saves man’s life in Norway! x.com/i/trending/199…

Great perspective on AI in education.

The next innovation that will really impress me is adding the ability to add future alarms. Something users have asked for since 2013 and @Apple has ignored. Two people I know have switched to android just because of this and I’m seriously considering it. Android has done this for a long time.

The wait is over. Introducing the new iPhone 17 Pro, iPhone Air, iPhone 17, Apple Watch Ultra 3, Apple Watch Series 11, Apple Watch SE 3, AirPods Pro 3, and more.

I wouldn’t brag about this @Uber AI support is the worst I’ve encountered to date. Just came out of an AI conference, experienced Ubers ai chatbot firsthand. After a ride never showed up and still charged me I spent 30 minutes dealing with the worst AI chatbot I’ve ever encountered and switched to @lyft. It’s bad examples like this that will give people bad impressions of the true potential of ai. Came out of this conference with so much excitement for ai then get slapped in the face with this horrible real world example. AI is not magic, still have some work to do, at least @uber does. My expectation is that it shouldn’t take 30 minutes to communicate that my driver never showed up and I never got in a ride I’m being charged for. I don’t think that’s too high of an expectation

@FireboltHQ @Uber @Uber AI support is the worst I’ve encountered to date. Just came out of an AI conference, experienced Ubers ai chatbot firsthand. After a ride never showed up and still charged me I spent 30 minutes dealing with the worst AI chatbot I’ve ever encountered and switched to @lyft

This time on the Data Engineering Show: Paarth Chothani from @Uber shares how they're innovating on-call support with AI 🤖 Highlights: 🔹How Uber built Genie to tackle the universal pain of on-call support 🔹The brilliant progression from basic documentation assistant to automated problem-solver 🔹Real examples of AI agents working together to resolve complex issues Tune in: firebolt.io/blog/building-… Spotify: bit.ly/4nZd6wE #AI #dataengineering #podcast

Great panel on AI and the patient experience. Discussed using AI to make visits more efficient to address physician burnout. I have a feeling that health systems will pay for AI to increase efficiency and then increase patient volumes, therefore sustaining burnout. Thoughts?

Such an exciting time. Looking forward to today’s sessions. Ai4

I will never understand why statisticians say “Type I error” and Type II error” when false positive and false negative are the same number of syllables and self-defining

Farewell to NHGRI, In 2023, I began my journey with NHGRI as a part-time contractor. Over time, my experience working alongside incredible colleagues led me to join full-time. However, being a remote worker and just one month shy of completing my probationary period, I was among the more vulnerable employees for the expected cuts. I opted for the deferred resignation program which turned out to be a wise decision. Before joining NHGRI, I must admit I held some misconceptions about government work. What I encountered, however, was a team of dedicated professionals—people who, in many cases, chose lower-paying roles to advance science. They cared deeply about their work, striving every day to make a meaningful impact. They were committed to supporting researchers, particularly early-career investigators, ensuring they had every opportunity to succeed. These were individuals who took genuine joy in others' successes, even knowing they’d receive little credit for their contributions. I have only positive things to say about NHGRI and can confidently attest to their careful stewardship of taxpayer dollars. Frankly, they could have used more funding. I have close relationships with people across the political spectrum, and while their perspectives may differ, I firmly believe that most people are good and want good things. Each side brings valuable viewpoints that, if combined, could complement each other. Shortly after the election, while flying from DC, I happened to sit across the aisle from a Republican senator. Amid concerns about my future, I asked about their perspective on NIH funding. While they couldn’t make promises, they assured me that NIH’s work was seen as critical and maintained strong bipartisan support. At the time, this gave me reassurance. And though recent events might suggest misplaced optimism, I still find comfort in that sentiment. Let me explain. I know this is a difficult time. Some truly great people have lost their jobs. My only solace is that their talent will ensure they find new opportunities. I still believe that support for science and innovation remains strong, regardless of political affiliation. There is broad recognition that many of the medical breakthroughs we benefit from today stem from NIH-funded research. The human drive to understand, to seek answers, is unyielding. Even through uncertainty, I trust that science will persevere. As for me, I’m setting out to explore my next chapter. I’ll find something—I’m not too worried about that. What concerns me more is the increasing polarization of our country. I hope for a future where we can sit down, engage in open conversations, disagree, and still appreciate the good in one another. We share far more common ground than we realize, and if there’s one area where unity is possible, it’s in our collective desire to improve human health. To my NHGRI colleagues—thank you. It has been an honor to work alongside you and I will always be grateful for the experience.

As a clinical geneticist I am very impressed with Grok's ability to provide answers to medical questions and the way it lays out the pros and cons of complex medical decisions. I see patients with rare disorders and it's been very useful as a digital "second opinion" providing all the appropriate references, saving a significant amount of time (not hallucinating the references like ChatGPT). It's impossible to know everything about the 10,000 plus disorders we see as geneticists. Anyone who has not tried this tool should.