Adrian Gervais

25 posts

Adrian Gervais

@grvsadrian

PhD @casanova_lab, @InstitutImagine. @AgroParisTech, @UnivParisSaclay & @univ_paris_cite alumni. Auto-antibodies, viruses, innate immunity, IEIs🔬

Paris, France Katılım Haziran 2023

296 Takip Edilen166 Takipçiler

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Adrian Gervais@grvsadrian·22 Eki

Grateful to have had the chance to present part of my work @ESIDsociety, with over 2,400 attendees! It was an amazing experience connecting with scientists from around the world and having insightful discussions. Can’t wait for the next edition!

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Adrian Gervais@grvsadrian·23 Eki

@ShenYingZhang1 Thank you SY for your mentorship!

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Shen-Ying Zhang@ShenYingZhang1·23 Eki

Our amazing PhD student—recently graduated 😊 presenting his works on the findings of autoantibodies against type I IFNs as major determinants of West Nile virus and tick-borne encephalitis. BRAVO @grvsadrian 👏

Adrian Gervais@grvsadrian

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ESID@ESIDsociety·17 Eki

The Phenocopies of IEI session at #ESID2024 features experts Steve Holland, @anne_puel, @BenHalePhD, Aude Magerus, Sophie Hambleton, and @grvsadrian exploring how similar phenotypes emerge from different genetic causes. #IEI #ESID

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Sébastien Nisole@SEBNisole·2 Eki

Just published in @NatureComms! We show that Usutu virus is the only mosquito-borne flavivirus to resist ISG20-mediated inhibition, thanks to a unique domain in its 3'UTR that protects its genome from degradation. A project led by @JimZPhD at @IRIM_life. rdcu.be/dVMK1

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Jeremie Rosain@JRosain·1 Eki

1/ Excited to report in @JExpMed more about the causes and consequences of human autoantibodies neutralizing type I IFNs through the study of a rare disease: shorturl.at/cWcCa

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Eric Topol@EricTopol·23 Eyl

About 10% of people who develop severe Covid have autoantibodies to Type 1 interferon, which doesn't get diagnosed. Now there's a simple assay. It's also relevant for other life-threatening viral illnesses, and these Abs exist in ~100 million people worldwide. pnas.org/doi/epub/10.10… @PNASNews @grvsadrian @casanova_lab

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Adrian Gervais@grvsadrian·26 Eyl

We report here in @PNASNews a simple assay to detect human type I interferon (IFN-I) deficiency. This test could revolutionize the diagnosis and management of patients with autoantibodies against IFN-I and inborn errors of immunity (IEI) affecting the IFN-I pathway!

Casanova Lab@casanova_lab

1/ We are excited to share a simple yet powerful whole blood assay to detect human type I interferon (IFN) deficiency...

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Adrian Gervais@grvsadrian·25 Eyl

Thrilled to share my second first-author paper out in @JExpMed. We show that about 10% of severe tick-borne encephalitis cases are due to auto-Abs neutralizing type I IFNs. Thanks to all our wonderful collaborators!

Casanova Lab@casanova_lab

1/ We are excited to share our report in #JEM that about 10% of severe tick-borne encephalitis (TBE) cases, triggered by the TBE virus (TBEV), are due to pre-existing auto-Abs neutralizing type I IFNs (doi.org/10.1084/jem.20…).

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Nicolas Berrod@nicolasberrod·21 Ağu

🦟 5 cas d'infections à virus du Nil occidental ont désormais été rapportés dans le Var, et plus de 70 dans toute l'Europe (dont 8 décès). L'infection, par piqûre de moustique, est généralement asymptomatique mais elle peut provoquer de rares formes neurologiques graves. 1/3

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Judith Aberle@AberleJudith·13 Ağu

West Nile virus season in full swing in Europe Austria reports 7 West Nile virus infections after mosquito bites (Lower Austria, Burgenland), including 3 hospitalized with neurological symptoms. One imported from Hungary Several others under investigation ecdc.europa.eu/en/news-events…

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Casanova Lab@casanova_lab·9 Tem

The title tells it all ! Severe West Nile virus and Sars-CoV-2 infections in a patient with thymoma and anti-type I IFN antibodies pubmed.ncbi.nlm.nih.gov/38976510/

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Adrian Gervais@grvsadrian·6 Ara

I was delighted to share my work about West Nile virus encephalitis at the @Encephalitis2023 in London! And this is an honor to be awarded with the best platform presentation🙏 I met great people in with outstanding scientific level. Thank you Ava and the team! 🧠🧑‍🔬🤩

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Encephalitis International@encephalitis·5 Ara

#Encephalitis2023 is now underway. @encephalitisava & Dr Nick Davies are leading the first session. Speakers include Dr Tarun Dua @WHO , Dr Sophia Michael, Dr Christine Strippel, @grvsadrian & Dr Tina Damodar. Excited to hear what they have to say about #encephalitis research.

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Adrian Gervais@grvsadrian·10 Kas

👏🙏🚀

Casanova Lab@casanova_lab

1/ We are excited to report in @Nature the discovery that human inborn errors of the alternative NF-κB pathway-dependent immunity underlie the development of auto-Abs neutralizing type I IFNs (rdcu.be/dqBBU).

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Adrian Gervais@grvsadrian·22 Eki

I will have the great honor of presenting part of my PhD work at the @encephalitis 2023 meeting next December, in London. Thanks a lot for the amazing opportunity! 🤩

Encephalitis International@encephalitis

#WestNile virus #encephalitis will be the topic when @grvsadrian joins our panel of speakers at Encephalitis 2023. Our annual conference, aimed at medical professionals of all levels, can be attended @RCPVenue #London or online in December. Tickets 👇 bit.ly/3rZNTdm

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Alessandro Borghesi@esiborghe·19 Eyl

Screening for auto-Abs neutralizing type I IFNs is key to design prevention strategies. Check out doi.org/10.1038/d43978… @grvsadrian @BarzonLuisa @ShenYingZhang1 @casanova_lab @JExpMed

Mukesh@mkyindian

US: Officials call for precaution as first death due to West Nile Virus reported in New Jersey dhunt.in/PmFfY #WestNileVirus

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Institut Imagine@InstitutImagine·28 Haz

Félicitations à @casanova_lab pour leur nouvel article dans @JExpMed ! Après leur rôle dans les formes sévères de COVID et de grippe, ils éclairent le lien des autoanticorps avec les formes sévères d'encéphalites dues au Virus du Nil @Inserm @APHP @univ_paris_cite

Casanova Lab@casanova_lab

1/ We are excited to share our report in @JExpMed showing that about 40% of cases of #WestNilevirus (#WNV) encephalitis are due to pre-existing auto-Abs neutralizing type I IFNs, making WNV encephalitis the best understood human infectious disease (rupress.org/jem/article/22…).

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