DavidHartnell

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DavidHartnell

DavidHartnell

@hartnell_david

PhD Student @ Curtin University Spectroscopy/Neuroscience/Synchrotron Science

Katılım Mart 2019
336 Takip Edilen81 Takipçiler
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Slava Bobrov
Slava Bobrov@slava__bobrov·
Network of brain cells in the cerebellum: #neuroscience by Giuseppe Gangarossa
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DavidHartnell
DavidHartnell@hartnell_david·
@drupad_t @TB_Perth @MaxMassi75 @CurtinChem @CHIRI_curtin One of the limitations is the need to keep the sample frozen. This makes sample prep and transportation more difficult and laborious. This also requires dry ice, adding an additional cost to each time you run the instrument.
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DavidHartnell retweetledi
Max Massi
Max Massi@MaxMassi75·
Brad presenting his @CurtinChem work on brain imaging with halogenated BODIPY probes at #ASMI2019
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DavidHartnell retweetledi
Interstellate
Interstellate@Interstellate_·
Neurons in the hippocampus projecting to the nucleus accumbens [Rabies-GFP in NAc; DAPI=blue; @Han_de_Jong]
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DavidHartnell
DavidHartnell@hartnell_david·
@reneewebs @CurtinChem We used brain tissue because neurons don't divide therefore, these deposits may give insight into the "biological history" of a cell. Our aim was to better understand the mechanisms behind oxidative stress during aging. For this method live patient analysis would not be viable :)
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DavidHartnell
DavidHartnell@hartnell_david·
@HollehButler @CurtinChem Hi Holly! These deposits display strong peaks in lipid regions but, there were no changes seen over the timepoints. We used a label free method for this study however SERS and fluorescent stains are techniques we want to look at in the future! I hope I answered your question :)
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Holly Butler
Holly Butler@HollehButler·
@hartnell_david @CurtinChem Hi David! Interesting study you have presented. Do these lipofuscin deposits have specific Raman peaks that can be monitored - perhaps in lipid regions? Could a techhniue such as SERS be used for labelling? #RSCPoster #RSCAnalytical
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