
Hunter Curry, PharmD
62 posts

Hunter Curry, PharmD
@hpcurry23
Pediatric Infectious Diseases 🦠








🆕🔥🦠 Mono vs Combo — S. maltophilia deep-seated infections | JAC AMR 2025 | 190 pts, monomicrobial 🚀 What they did Focus on levofloxacin-based combos Propensity-weighted analysis 🔥 Key findings 💊 Levo + minocycline: ~12% clinical failure (vs 30% monotherapy) 💊 Levo + TMP/SMX: ~8% clinical failure (vs 30% monotherapy) ⚠️ Higher risk of Rx failure: high SOFA, prior carbapenems, empyema 💡⚡ Takeaway Levo combos may reduce clinical failure in deep-seated S. maltophilia infections. Prospective trials are warranted #IDXposts academic.oup.com/jacamr/article…












🆕💫 New narrative review challenges the longstanding reliance on TMP-SMX for treatment of Stenotrophomonas infections—citing PK/PD concerns and rising resistance. Also questions mono vs combo use. Clinical data still limited. Worth a close read! #IDXposts sciencedirect.com/science/articl…










