Nick-RZA

Polymarket was paying $50k/day to market makers at one point. Now it's $0.025 per $100 traded. That collapse tells you everything about why prediction markets are still in beta: @nick.c.ruzicka/prediction-markets-are-having-a-moment-9b0924507ad3" target="_blank" rel="nofollow noopener">medium.com/@nick.c.ruzick…

Crypto Twitter has no idea 10 thousand people are making predictions on BTC 1 minute charts every day

🚨 Holy shit...A developer on GitHub just built a full development methodology for AI coding agents and it has 40.9K stars on GitHub. It's called Superpowers, and it completely changes how your AI agent writes code. Right now, most people fire up Claude Code or Codex and just… let it go. The agent guesses what you want, writes code before understanding the problem, skips tests, and produces spaghetti you have to babysit. Superpowers fixes all of that. Here's what happens when you install it: → Before writing a single line, the agent stops and brainstorms with you. It asks what you're actually trying to build, refines the spec through questions, and shows it to you in chunks short enough to read. → Once you approve the design, it creates an implementation plan so detailed that "an enthusiastic junior engineer with poor taste and no judgement" could follow it. → Then it launches subagent-driven development. Fresh subagents per task. Two-stage code review after each one (spec compliance, then code quality). The agent can run autonomously for hours without deviating from your plan. → It enforces true test-driven development. Write failing test → watch it fail → write minimal code → watch it pass → commit. It literally deletes code written before tests. → When tasks are done, it verifies everything, presents options (merge, PR, keep, discard), and cleans up. The philosophy is brutal: systematic over ad-hoc. Evidence over claims. Complexity reduction. Verify before declaring success. Works with Claude Code (plugin install), Codex, and OpenCode. This isn't a prompt template. It's an entire operating system for how AI agents should build software. 100% Opensource. MIT License.

@iamliamsheridan codex

your competitors are researching their prospects with AI. not every prospect. the right ones. using 6 layers of automated research to find the signal that makes a cold email feel like it was written by someone who did their homework. without spending 45 minutes per account. the AI prospect research stack: -> 6 research layers in sequence -> the models that handle each layer -> prompt structure that returns usable output first time -> how to build this as a background process that runs automatically -> the personalisation variable format that feeds into your email templates comment CODEX and i'll send it over. (must be following)

@ryantrost big time

@dannygreene @StasXion you and me both. started strong then got a little risky at the end

@StasXion I'm losing so far...

Linera is breaking new ground with 1m up/down prediction markets. Grab a strong cup of coffee ☕️ and start playing. (Still testnet. Mo money at risk, but you earn portal points for playing.) Thoughts so far?

Short duration crypto markets are the hottest thing in the game right now Only @linera_io will own the whole stack. Chain, app, token. All-in-one.

@THArrowOfApollo Code

We were Clay's largest user at one point in time, hitting their platform 17.3 million times per week. Last month we replaced them entirely with a $200/mo Claude Code subscription. I can't write code. Neither can James, my VP of Growth who built the replacement. Here's the full story. Clay is a GREAT product and I TRULY think most people should use it. But we hit their ceiling. 50,000 row limit per table. 12.5 million row cap per workspace. Tables that take days to actually delete. Clicking "run all" thousands of times and waiting days for things to clear out. So When you're processing millions of leads, all the above become the bottleneck of your entire business. James had never touched Claude Code before. Three weeks after learning it, he built our entire core system. With Clay, processing 1 million leads took 27 hours. And it would error out often enough that we would always have to plan on hitting the “run all rows” button again on 20+ clay tables. IYKYK but Our new system waterfall enriches 1 million leads in 5 seconds. 272,000 leads PER SECOND. AND On top of the core engine, we vibe coded a Google Maps scraper that pulls leads zip code by zip code across all 32,000 US zip codes. AND An AI lead finder that hits 95% contact match rates where Apollo gives you about 30%. AND Ad library scrapers for Google and LinkedIn. AND An AI campaign analysis system. AND An auto-refill system so clients never run out of leads mid-campaign. One we started building with Claude, we just couldn’t stop Now we have the data ready for clients sending 5 million emails a month within 1 week of signing the contract. I put together the full system blueprint -- every tool, the tech stack, a Clay vs custom comparison, and a 6-step playbook for building your own. Plus a video walkthrough where I show you the live system and how each tool actually works. Retweet or Reply CODE below and I'll DM it to you.

@VihaarNandigala Claw

We built something a little dangerous for GTM teams. It’s called GTM Claw. A workflow library that turns OpenClaw + Claude Code into a customer-finding machine. Think: • Find people talking about your problem on Reddit, LinkedIn, Twitter • Identify companies showing buying signals • Enrich decision makers automatically • Check ICP fit • Push qualified leads into sequences or your CRM Just continuous discovery of in-market accounts. We’ve been using it internally at Orange Slice to: • scrape LinkedIn reactors on competitors’ posts • detect product complaints on Reddit • identify operators switching companies • surface companies hiring GTM engineers We’re opening GTM Claw in beta. Only 100 users for the next couple months. ~30 spots already filled. If you want access: Comment “CLAW” and follow me so I can dm you the link. Turn Claude Code + Open Claw into a GTM menace. 🦞

1/ kalshi banned two insiders this week and reported both to the cftc. one was a mrbeast editor betting on mrbeast markets. the other worked at a company whose acquisition he was trading on. first public enforcement actions. not the last.

@ryantrost @_dew911 @linera_m0x @linera_m0x - has been cooking indeed

We used OpenClaw to turn our chain mascot @linera_m0x into a live operations master Right now, it helps manage a team of agents seeding 6000 markets per day and testing dozens of automated trading strategies to prepare us for launch

@capitalismandf1 @cremieuxrecueil @tbpn @hubermanlab I was wrong on that one: the retatrutide DXA substudy (Coskun et al., Lancet D&E 2025, n=103) and tirzepatide’s SURMOUNT-1 DXA substudy both show the same ~75/25 fat/lean ratio, so no muscle-sparing advantage demonstrated. My bad

@hyperreal_nick @cremieuxrecueil @tbpn @hubermanlab Link? What was the n? Was it a RCT?

“This is going to be a trillion-dollar drug.” @hubermanlab says retatrutide is the peptide that’s about to “change everything.” Currently in a Phase III clinical trial in humans, retatrutide caused up to one-third body weight loss in just six months, with some degree of muscle sparing. “The bodybuilding community has been onto this for a long time.” “Then it shows up in Hollywood. Everyone lies or avoids answering the question of how they got so jacked. They talk about eating chicken breasts, and they’re actually taking growth hormone, Winstrol, and retatrutide.” “We are looking at a potential change in the laws around peptides such that buying peptides would become illegal. I think this is a terrible idea, but the motivation behind this is largely because Eli Lilly owns the patent.” “Lilly would like to protect the domain over that patent. This is going to be a trillion-dollar drug.”

@cremieuxrecueil @tbpn @hubermanlab The lean mass claim ignores the actual DXA substudy data: retatrutide shows ~25% lean loss vs. ~40% for semaglutide, which is a meaningful difference even if no direct head-to-head trial exists yet.

@tbpn @hubermanlab There's no indication of muscle-sparing relative to other GLP-1RAs or normal weight loss in trials yet. If I had to guess, the trillion dollar drug won't just be tirzepatide-plus, it'll be one that's longer-acting.

@maxmarchione @TheMrLawgiver This is at the 12mg dose after 24 weeks. Most people don't need that much.

@TheMrLawgiver It increases heart rate and reduces HRV, which is the opposite of what is generally health

Many people I know who started reta have gone back to tirz. I think reta will be a gateway to GLP1s but then folks will go to tirz microdose for maintenance because it’s safer

@ryantrost @_dew911 🫡

I am testing 1 minute up down markets on Linera Markets and it is absolute crack Gmarkets

@predofficial LFG